Combination cancer immunotherapy and new immunomodulatory targets
Mahoney, Kathleen M., Rennert, Paul D., Freeman, Gordon J.
Published in Nature reviews. Drug discovery (01.08.2015)
Published in Nature reviews. Drug discovery (01.08.2015)
Get full text
Journal Article
ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity
Maazi, Hadi, Patel, Nisheel, Sankaranarayanan, Ishwarya, Suzuki, Yuzo, Rigas, Diamanda, Soroosh, Pejman, Freeman, Gordon J., Sharpe, Arlene H., Akbari, Omid
Published in Immunity (Cambridge, Mass.) (17.03.2015)
Published in Immunity (Cambridge, Mass.) (17.03.2015)
Get full text
Journal Article
Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family
Schildberg, Frank A., Klein, Sarah R., Freeman, Gordon J., Sharpe, Arlene H.
Published in Immunity (Cambridge, Mass.) (17.05.2016)
Published in Immunity (Cambridge, Mass.) (17.05.2016)
Get full text
Journal Article
Coinhibitory Pathways in Immunotherapy for Cancer
Baumeister, Susanne H, Freeman, Gordon J, Dranoff, Glenn, Sharpe, Arlene H
Published in Annual review of immunology (20.05.2016)
Published in Annual review of immunology (20.05.2016)
Get full text
Journal Article
Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
Zhang, Jinfang, Bu, Xia, Wang, Haizhen, Zhu, Yasheng, Geng, Yan, Nihira, Naoe Taira, Tan, Yuyong, Ci, Yanpeng, Wu, Fei, Dai, Xiangpeng, Guo, Jianping, Huang, Yu-Han, Fan, Caoqi, Ren, Shancheng, Sun, Yinghao, Freeman, Gordon J., Sicinski, Piotr, Wei, Wenyi
Published in Nature (London) (04.01.2018)
Published in Nature (London) (04.01.2018)
Get full text
Journal Article
The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma
Mahoney, Kathleen M., MD, PhD, Freeman, Gordon J., PhD, McDermott, David F., MD
Published in Clinical therapeutics (01.04.2015)
Published in Clinical therapeutics (01.04.2015)
Get full text
Journal Article
Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy
Chow, Melvyn T., Ozga, Aleksandra J., Servis, Rachel L., Frederick, Dennie T., Lo, Jennifer A., Fisher, David E., Freeman, Gordon J., Boland, Genevieve M., Luster, Andrew D.
Published in Immunity (Cambridge, Mass.) (18.06.2019)
Published in Immunity (Cambridge, Mass.) (18.06.2019)
Get full text
Journal Article
Emerging concepts in PD-1 checkpoint biology
Pauken, Kristen E., Torchia, James A., Chaudhri, Apoorvi, Sharpe, Arlene H., Freeman, Gordon J.
Published in Seminars in immunology (01.02.2021)
Published in Seminars in immunology (01.02.2021)
Get full text
Journal Article
T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
Schmid, Daniela, Park, Chun Gwon, Hartl, Christina A., Subedi, Nikita, Cartwright, Adam N., Puerto, Regina Bou, Zheng, Yiran, Maiarana, James, Freeman, Gordon J., Wucherpfennig, Kai W., Irvine, Darrell J., Goldberg, Michael S.
Published in Nature communications (23.11.2017)
Published in Nature communications (23.11.2017)
Get full text
Journal Article
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
Pfirschke, Christina, Engblom, Camilla, Rickelt, Steffen, Cortez-Retamozo, Virna, Garris, Christopher, Pucci, Ferdinando, Yamazaki, Takahiro, Poirier-Colame, Vichnou, Newton, Andita, Redouane, Younes, Lin, Yi-Jang, Wojtkiewicz, Gregory, Iwamoto, Yoshiko, Mino-Kenudson, Mari, Huynh, Tiffany G., Hynes, Richard O., Freeman, Gordon J., Kroemer, Guido, Zitvogel, Laurence, Weissleder, Ralph, Pittet, Mikael J.
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Published in Immunity (Cambridge, Mass.) (16.02.2016)
Get full text
Journal Article
In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy
Arlauckas, Sean P, Garris, Christopher S, Kohler, Rainer H, Kitaoka, Maya, Cuccarese, Michael F, Yang, Katherine S, Miller, Miles A, Carlson, Jonathan C, Freeman, Gordon J, Anthony, Robert M, Weissleder, Ralph, Pittet, Mikael J
Published in Science translational medicine (10.05.2017)
Published in Science translational medicine (10.05.2017)
Get more information
Journal Article
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
Gao, Yang, Nihira, Naoe Taira, Bu, Xia, Chu, Chen, Zhang, Jinfang, Kolodziejczyk, Aleksandra, Fan, Yizeng, Chan, Ngai Ting, Ma, Leina, Liu, Jing, Wang, Dong, Dai, Xiaoming, Liu, Huadong, Ono, Masaya, Nakanishi, Akira, Inuzuka, Hiroyuki, North, Brian J., Huang, Yu-Han, Sharma, Samanta, Geng, Yan, Xu, Wei, Liu, X. Shirley, Li, Lei, Miki, Yoshio, Sicinski, Piotr, Freeman, Gordon J., Wei, Wenyi
Published in Nature cell biology (01.09.2020)
Published in Nature cell biology (01.09.2020)
Get full text
Journal Article
PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome
Roemer, Margaretha G M, Advani, Ranjana H, Ligon, Azra H, Natkunam, Yasodha, Redd, Robert A, Homer, Heather, Connelly, Courtney F, Sun, Heather H, Daadi, Sarah E, Freeman, Gordon J, Armand, Philippe, Chapuy, Bjoern, de Jong, Daphne, Hoppe, Richard T, Neuberg, Donna S, Rodig, Scott J, Shipp, Margaret A
Published in Journal of clinical oncology (10.08.2016)
Published in Journal of clinical oncology (10.08.2016)
Get full text
Journal Article
Topological analysis reveals a PD-L1-associated microenvironmental niche for Reed-Sternberg cells in Hodgkin lymphoma
Carey, Christopher D., Gusenleitner, Daniel, Lipschitz, Mikel, Roemer, Margaretha G.M., Stack, Edward C., Gjini, Evisa, Hu, Xihao, Redd, Robert, Freeman, Gordon J., Neuberg, Donna, Hodi, F. Stephen, Liu, Xiaole Shirley, Shipp, Margaret A., Rodig, Scott J.
Published in Blood (30.11.2017)
Published in Blood (30.11.2017)
Get full text
Journal Article
TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response
Zeng, Zexian, Wong, Cheryl J, Yang, Lin, Ouardaoui, Nofal, Li, Dian, Zhang, Wubing, Gu, Shengqing, Zhang, Yi, Liu, Yang, Wang, Xiaoqing, Fu, Jingxin, Zhou, Liye, Zhang, Boning, Kim, Sarah, Yates, Kathleen B, Brown, Myles, Freeman, Gordon J, Uppaluri, Ravindra, Manguso, Robert, Liu, X Shirley
Published in Nucleic acids research (07.01.2022)
Published in Nucleic acids research (07.01.2022)
Get full text
Journal Article
Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer
Giraldo, Nicolas A, Becht, Etienne, Pagès, Franck, Skliris, Georgios, Verkarre, Virginie, Vano, Yann, Mejean, Arnaud, Saint-Aubert, Nicolas, Lacroix, Laetitia, Natario, Ivo, Lupo, Audrey, Alifano, Marco, Damotte, Diane, Cazes, Aurelie, Triebel, Frederic, Freeman, Gordon J, Dieu-Nosjean, Marie-Caroline, Oudard, Stephane, Fridman, Wolf H, Sautès-Fridman, Catherine
Published in Clinical cancer research (01.07.2015)
Published in Clinical cancer research (01.07.2015)
Get full text
Journal Article
PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer
Ding, Liya, Kim, Hye-Jung, Wang, Qiwei, Kearns, Michael, Jiang, Tao, Ohlson, Carolynn E., Li, Ben B., Xie, Shaozhen, Liu, Joyce F., Stover, Elizabeth H., Howitt, Brooke E., Bronson, Roderick T., Lazo, Suzan, Roberts, Thomas M., Freeman, Gordon J., Konstantinopoulos, Panagiotis A., Matulonis, Ursula A., Zhao, Jean J.
Published in Cell reports (Cambridge) (11.12.2018)
Published in Cell reports (Cambridge) (11.12.2018)
Get full text
Journal Article
PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies
CHEN, Benjamin J, CHAPUY, Bjoern, RODIG, Scott J, OUYANG, Jing, SUN, Heather H, ROEMER, Margaretha G. M, XU, Mina L, HONGBO YU, FLETCHER, Christopher D. M, FREEMAN, Gordon J, SHIPP, Margaret A
Published in Clinical cancer research (01.07.2013)
Published in Clinical cancer research (01.07.2013)
Get full text
Journal Article
TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine
Jemielity, Stephanie, Wang, Jinyize J, Chan, Ying Kai, Ahmed, Asim A, Li, Wenhui, Monahan, Sheena, Bu, Xia, Farzan, Michael, Freeman, Gordon J, Umetsu, Dale T, Dekruyff, Rosemarie H, Choe, Hyeryun
Published in PLoS pathogens (01.03.2013)
Published in PLoS pathogens (01.03.2013)
Get full text
Journal Article