Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models
Biczo, Gyorgy, Vegh, Eszter T., Shalbueva, Natalia, Mareninova, Olga A., Elperin, Jason, Lotshaw, Ethan, Gretler, Sophie, Lugea, Aurelia, Malla, Sudarshan R., Dawson, David, Ruchala, Piotr, Whitelegge, Julian, French, Samuel W., Wen, Li, Husain, Sohail Z., Gorelick, Fred S., Hegyi, Peter, Rakonczay, Zoltan, Gukovsky, Ilya, Gukovskaya, Anna S.
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2018)
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CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation
Esteghamat, Fatemehsadat, Broughton, James S., Smith, Emily, Cardone, Rebecca, Tyagi, Tarun, Guerra, Mateus, Szabó, András, Ugwu, Nelson, Mani, Mitra V., Azari, Bani, Kayingo, Gerald, Chung, Sunny, Fathzadeh, Mohsen, Weiss, Ephraim, Bender, Jeffrey, Mane, Shrikant, Lifton, Richard P., Adeniran, Adebowale, Nathanson, Michael H., Gorelick, Fred S., Hwa, John, Sahin-Tóth, Miklós, Belfort-DeAguiar, Renata, Kibbey, Richard G., Mani, Arya
Published in Nature genetics (01.08.2019)
Published in Nature genetics (01.08.2019)
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Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinoma
Gao, Yasheen, Wang, Melinda, Guo, Xiaojia, Hu, Joanna, Chen, Tian-Min, Finn, Sade M B, Lacy, Jill, Kunstman, John W, Cha, Charles H, Bellin, Melena D, Robert, Marie E, Desir, Gary V, Gorelick, Fred S
Published in PloS one (29.09.2021)
Published in PloS one (29.09.2021)
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Chronic Nicotine Exposure In Vivo and In Vitro Inhibits Vitamin B1 (Thiamin) Uptake by Pancreatic Acinar Cells
Srinivasan, Padmanabhan, Thrower, Edwin C, Loganathan, Gopalakrishnan, Balamurugan, A N, Subramanian, Veedamali S, Gorelick, Fred S, Said, Hamid M
Published in PloS one (03.12.2015)
Published in PloS one (03.12.2015)
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Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats
Bhoomagoud, Madhavi, Jung, Thomas, Atladottir, Jorunn, Kolodecik, Thomas R, Shugrue, Christine, Chaudhuri, Anamika, Thrower, Edwin C, Gorelick, Fred S
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2009)
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Renalase: A Multi-Functional Signaling Molecule with Roles in Gastrointestinal Disease
Pointer, Thomas C, Gorelick, Fred S, Desir, Gary V
Published in Cells (Basel, Switzerland) (06.08.2021)
Published in Cells (Basel, Switzerland) (06.08.2021)
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Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
Srinivasan, Padmanabhan, Thrower, Edwin C, Gorelick, Fred S, Said, Hamid M
Published in American journal of physiology: Gastrointestinal and liver physiology (15.05.2016)
Published in American journal of physiology: Gastrointestinal and liver physiology (15.05.2016)
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Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis
Gukovskaya, Anna S, Vaquero, Eva, Zaninovic, Vjekoslav, Gorelick, Fred S, Lusis, Aldons J, Brennan, Marie-Luise, Holland, Steven, Pandol, Stephen J
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2002)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2002)
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The Identification of a Novel Endoplasmic Reticulum to Golgi SNARE Complex Used by the Prechylomicron Transport Vesicle
Siddiqi, Shadab A., Siddiqi, Shahzad, Mahan, James, Peggs, Kiffany, Gorelick, Fred S., Mansbach, Charles M.
Published in The Journal of biological chemistry (28.07.2006)
Published in The Journal of biological chemistry (28.07.2006)
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Phospholipase D1 Corrects Impaired βAPP Trafficking and Neurite Outgrowth in Familial Alzheimer's Disease-Linked Presenilin-1 Mutant Neurons
Cai, Dongming, Zhong, Minghao, Wang, Runsheng, Netzer, William J., Shields, Dennis, Zheng, Hui, Sisodia, Sangram S., Foster, David A., Gorelick, Fred S., Xu, Huaxi, Greengard, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
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Impaired Membrane Resealing and Autoimmune Myositis in Synaptotagmin VII-Deficient Mice
Chakrabarti, Sabyasachi, Kobayashi, Koichi S., Flavell, Richard A., Marks, Carolyn B., Miyake, Katsuya, Liston, David R., Fowler, Kimberly T., Gorelick, Fred S., Andrews, Norma W.
Published in The Journal of cell biology (18.08.2003)
Published in The Journal of cell biology (18.08.2003)
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Journal Article
Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells
Kolodecik, Thomas R, Shugrue, Christine A, Thrower, Edwin C, Levin, Lonny R, Buck, Jochen, Gorelick, Fred S
Published in PloS one (23.07.2012)
Published in PloS one (23.07.2012)
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Presenilin-1 Uses Phospholipase D1 as a Negative Regulator of β-Amyloid Formation
Cai, Dongming, Netzer, William J., Zhong, Minghao, Lin, Yixin, Du, Guangwei, Frohman, Michael, Foster, David A., Sisodia, Sangram S., Xu, Huaxi, Gorelick, Fred S., Greengard, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (07.02.2006)
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Journal Article
Low Extracellular pH Induces Damage in the Pancreatic Acinar Cell by Enhancing Calcium Signaling
Reed, Anamika M., Husain, Sohail Z., Thrower, Edwin, Alexandre, Martine, Shah, Ahsan, Gorelick, Fred S., Nathanson, Michael H.
Published in The Journal of biological chemistry (21.01.2011)
Published in The Journal of biological chemistry (21.01.2011)
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Journal Article
The Ryanodine Receptor Mediates Early Zymogen Activation in Pancreatitis
Husain, Sohail Z., Prasad, Priyajit, Grant, Wayne M., Kolodecik, Thomas R., Nathanson, Michael H., Gorelick, Fred S., Greengard, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2005)
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