Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling
He, Guobin, Dhar, Debanjan, Nakagawa, Hayato, Font-Burgada, Joan, Ogata, Hisanobu, Jiang, Yuhong, Shalapour, Shabnam, Seki, Ekihiro, Yost, Shawn E., Jepsen, Kristen, Frazer, Kelly A., Harismendy, Olivier, Hatziapostolou, Maria, Iliopoulos, Dimitrios, Suetsugu, Atsushi, Hoffman, Robert M., Tateishi, Ryosuke, Koike, Kazuhiko, Karin, Michael
Published in Cell (10.10.2013)
Published in Cell (10.10.2013)
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Human genetic variation and its contribution to complex traits
Frazer, Kelly A, Murray, Sarah S, Schork, Nicholas J, Topol, Eric J
Published in Nature reviews. Genetics (01.04.2009)
Published in Nature reviews. Genetics (01.04.2009)
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Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression
Greenwald, William W., Li, He, Benaglio, Paola, Jakubosky, David, Matsui, Hiroko, Schmitt, Anthony, Selvaraj, Siddarth, D’Antonio, Matteo, D’Antonio-Chronowska, Agnieszka, Smith, Erin N., Frazer, Kelly A.
Published in Nature communications (05.03.2019)
Published in Nature communications (05.03.2019)
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ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis
Zipeto, Maria Anna, Court, Angela C., Sadarangani, Anil, Delos Santos, Nathaniel P., Balaian, Larisa, Chun, Hye-Jung, Pineda, Gabriel, Morris, Sheldon R., Mason, Cayla N., Geron, Ifat, Barrett, Christian, Goff, Daniel J., Wall, Russell, Pellecchia, Maurizio, Minden, Mark, Frazer, Kelly A., Marra, Marco A., Crews, Leslie A., Jiang, Qingfei, Jamieson, Catriona H.M.
Published in Cell stem cell (04.08.2016)
Published in Cell stem cell (04.08.2016)
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Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells
DeBoever, Christopher, Li, He, Jakubosky, David, Benaglio, Paola, Reyna, Joaquin, Olson, Katrina M., Huang, Hui, Biggs, William, Sandoval, Efren, D’Antonio, Matteo, Jepsen, Kristen, Matsui, Hiroko, Arias, Angelo, Ren, Bing, Nariai, Naoki, Smith, Erin N., D’Antonio-Chronowska, Agnieszka, Farley, Emma K., Frazer, Kelly A.
Published in Cell stem cell (06.04.2017)
Published in Cell stem cell (06.04.2017)
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miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1
Mraz, Marek, Chen, Liguang, Rassenti, Laura Z., Ghia, Emanuela M., Li, Hongying, Jepsen, Kristen, Smith, Erin N., Messer, Karen, Frazer, Kelly A., Kipps, Thomas J.
Published in Blood (03.07.2014)
Published in Blood (03.07.2014)
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Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers
DeBoever, Christopher, Ghia, Emanuela M, Shepard, Peter J, Rassenti, Laura, Barrett, Christian L, Jepsen, Kristen, Jamieson, Catriona H M, Carson, Dennis, Kipps, Thomas J, Frazer, Kelly A
Published in PLoS computational biology (01.03.2015)
Published in PLoS computational biology (01.03.2015)
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PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3
Benitez, Jorge A., Ma, Jianhui, D’Antonio, Matteo, Boyer, Antonia, Camargo, Maria Fernanda, Zanca, Ciro, Kelly, Stephen, Khodadadi-Jamayran, Alireza, Jameson, Nathan M., Andersen, Michael, Miletic, Hrvoje, Saberi, Shahram, Frazer, Kelly A., Cavenee, Webster K., Furnari, Frank B.
Published in Nature communications (12.05.2017)
Published in Nature communications (12.05.2017)
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High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer
Schmidt, Tobias T., Tyer, Carly, Rughani, Preeyesh, Haggblom, Candy, Jones, Jeffrey R., Dai, Xiaoguang, Frazer, Kelly A., Gage, Fred H., Juul, Sissel, Hickey, Scott, Karlseder, Jan
Published in Nature communications (18.06.2024)
Published in Nature communications (18.06.2024)
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In heart failure reactivation of RNA-binding proteins is associated with the expression of 1,523 fetal-specific isoforms
D'Antonio, Matteo, Nguyen, Jennifer P, Arthur, Timothy D, Matsui, Hiroko, Donovan, Margaret K R, D'Antonio-Chronowska, Agnieszka, Frazer, Kelly A
Published in PLoS computational biology (01.02.2022)
Published in PLoS computational biology (01.02.2022)
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Evaluation of next generation sequencing platforms for population targeted sequencing studies
Harismendy, Olivier, Ng, Pauline C, Strausberg, Robert L, Wang, Xiaoyun, Stockwell, Timothy B, Beeson, Karen Y, Schork, Nicholas J, Murray, Sarah S, Topol, Eric J, Levy, Samuel, Frazer, Kelly A
Published in Genome biology (27.03.2009)
Published in Genome biology (27.03.2009)
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Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk
Greenwald, William W., Chiou, Joshua, Yan, Jian, Qiu, Yunjiang, Dai, Ning, Wang, Allen, Nariai, Naoki, Aylward, Anthony, Han, Jee Yun, Kadakia, Nikita, Regue, Laura, Okino, Mei-Lin, Drees, Frauke, Kramer, Dana, Vinckier, Nicholas, Minichiello, Liliana, Gorkin, David, Avruch, Joseph, Frazer, Kelly A., Sander, Maike, Ren, Bing, Gaulton, Kyle J.
Published in Nature communications (07.05.2019)
Published in Nature communications (07.05.2019)
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Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders
Zhou, Dan, Udpa, Nitin, Ronen, Roy, Stobdan, Tsering, Liang, Junbin, Appenzeller, Otto, Zhao, Huiwen W., Yin, Yi, Du, Yuanping, Guo, Lixia, Cao, Rui, Wang, Yu, Jin, Xin, Huang, Chen, Jia, Wenlong, Cao, Dandan, Guo, Guangwu, Gamboa, Jorge L., Villafuerte, Francisco, Callacondo, David, Xue, Jin, Liu, Siqi, Frazer, Kelly A., Li, Yingrui, Bafna, Vineet, Haddad, Gabriel G.
Published in American journal of human genetics (05.09.2013)
Published in American journal of human genetics (05.09.2013)
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Genomewide SNP Variation Reveals Relationships among Landraces and Modern Varieties of Rice
McNally, Kenneth L., Childs, Kevin L., Bohnert, Regina, Davidson, Rebecca M., Zhao, Keyan, Ulat, Victor J., Zeller, Georg, Clark, Richard M., Hoen, Douglas R., Bureau, Thomas E., Stokowski, Renee, Ballinger, Dennis G., Frazer, Kelly A., Cox, David R., Padhukasahasram, Badri, Bustamante, Carlos D., Weigel, Detlef, Mackill, David J., Bruskiewich, Richard M., Rätsch, Gunnar, Buell, C. Robin, Leung, Hei, Leach, Jan E., Phillips, Ronald L.
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2009)
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Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy
Barrett, Christian L., DeBoever, Christopher, Jepsen, Kristen, Saenz, Cheryl C., Carson, Dennis A., Frazer, Kelly A.
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (09.06.2015)
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ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia
Jiang, Qingfei, Crews, Leslie A., Barrett, Christian L., Chun, Hye-Jung, Court, Angela C., Isquith, Jane M., Zipeto, Maria A., Goff, Daniel J., Minden, Mark, Sadarangani, Anil, Rusert, Jessica M., Dao, Kim-Hien T., Morris, Sheldon R., Goldstein, Lawrence S. B., Marra, Marco A., Frazer, Kelly A., Jamieson, Catriona H. M.
Published in Proceedings of the National Academy of Sciences - PNAS (15.01.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (15.01.2013)
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Mutations in topoisomerase IIβ result in a B cell immunodeficiency
Broderick, Lori, Yost, Shawn, Li, Dong, McGeough, Matthew D., Booshehri, Laela M., Guaderrama, Marisela, Brydges, Susannah D., Kucharova, Karolina, Patel, Niraj C., Harr, Margaret, Hakonarson, Hakon, Zackai, Elaine, Cowell, Ian G., Austin, Caroline A., Hügle, Boris, Gebauer, Corinna, Zhang, Jianguo, Xu, Xun, Wang, Jian, Croker, Ben A., Frazer, Kelly A., Putnam, Christopher D., Hoffman, Hal M.
Published in Nature communications (13.08.2019)
Published in Nature communications (13.08.2019)
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