Real time on‐line amino acid analysis to explore amino acid trends and link to glycosylation outcomes of a model monoclonal antibody
Azer, Nicole, Trunfio, Nicholas, Fratz‐Berilla, Erica J., Hong, Jin Sung, Cullinan, Jackie, Faison, Talia, Agarabi, Cyrus D., Powers, David N.
Published in Biotechnology progress (01.07.2023)
Published in Biotechnology progress (01.07.2023)
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Journal Article
Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events
Fratz‐Berilla, Erica J., Angart, Phillip, Graham, Ryan J., Powers, David N., Mohammad, Adil, Kohnhorst, Casey, Faison, Talia, Velugula‐Yellela, Sai Rashmika, Trunfio, Nicholas, Agarabi, Cyrus
Published in Biotechnology and bioengineering (01.09.2020)
Published in Biotechnology and bioengineering (01.09.2020)
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Journal Article
Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures
Fratz‐Berilla, Erica J., Faison, Talia, Kohnhorst, Casey L., Velugula‐Yellela, Sai Rashmika, Powers, David N., Brorson, Kurt, Agarabi, Cyrus
Published in Biotechnology and bioengineering (01.12.2019)
Published in Biotechnology and bioengineering (01.12.2019)
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Journal Article
Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality
Powers, David N., Wang, Yifan, Fratz‐Berilla, Erica J., Velugula‐Yellela, Sai Rashmika, Chavez, Brittany, Angart, Phillip, Trunfio, Nicholas, Yoon, Seongkyu, Agarabi, Cyrus
Published in Biotechnology progress (01.11.2019)
Published in Biotechnology progress (01.11.2019)
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Journal Article
Evaluation of single-use optical and electrochemical pH sensors in upstream bioprocessing
Fratz-Berilla, Erica J., Kohnhorst, Casey, Trunfio, Nicholas, Bush, Xin, Gyorgypal, Aron, Agarabi, Cyrus
Published in Heliyon (15.02.2024)
Published in Heliyon (15.02.2024)
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Journal Article
Defining Golden Batches in Biomanufacturing Processes From Internal Metabolic Activity to Detect Process Changes That May Affect Product Quality
Bush, Xin, Fratz-Berilla, Erica J, Kohnhorst, Casey L, King, Roberta, Agarabi, Cyrus, Powers, David N, Trunfio, Nicholas
Published in Biotechnology and bioengineering (27.10.2024)
Published in Biotechnology and bioengineering (27.10.2024)
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Journal Article
Primary Clarification of CHO Harvested Cell Culture Fluid using an Acoustic Separator
Hong, Jin Sung, Azer, Nicole, Agarabi, Cyrus, Fratz-Berilla, Erica J.
Published in Journal of visualized experiments (14.05.2020)
Published in Journal of visualized experiments (14.05.2020)
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Journal Article
Differential effects of bioreactor process variables and purification on the human recombinant lysosomal enzyme β-glucuronidase produced from Chinese hamster ovary cells
Parhiz, Hamideh, Ketcham, Stephanie A., Zou, Guozhang, Ghosh, Bidesh, Fratz-Berilla, Erica J., Ashraf, Muhammad, Ju, Tongzhong, Madhavarao, Chikkathur N.
Published in Applied microbiology and biotechnology (01.08.2019)
Published in Applied microbiology and biotechnology (01.08.2019)
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Journal Article
Isoniazid inhibits human erythroid 5-aminolevulinate synthase: Molecular mechanism and tolerance study with four X-linked protoporphyria patients
Fratz-Berilla, Erica J., Breydo, Leonid, Gouya, Laurent, Puy, Hervé, Uversky, Vladimir N., Ferreira, Gloria C.
Published in Biochimica et biophysica acta. Molecular basis of disease (01.02.2017)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.02.2017)
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Journal Article
An improved purification method for the lysosomal storage disease protein β-glucuronidase produced in CHO cells
Fratz-Berilla, Erica J., Ketcham, Stephanie A., Parhiz, Hamideh, Ashraf, Muhammad, Madhavarao, Chikkathur N.
Published in Protein expression and purification (01.12.2017)
Published in Protein expression and purification (01.12.2017)
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Journal Article
Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System
Velugula-Yellela, Sai Rashmika, Powers, David N, Angart, Phillip, Faustino, Anneliese, Faison, Talia, Kohnhorst, Casey, Fratz-Berilla, Erica J, Agarabi, Cyrus D
Published in Journal of visualized experiments (01.05.2019)
Published in Journal of visualized experiments (01.05.2019)
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Journal Article
Bioprocess: Robustness with Respect to Mycoplasma Species
Faison, Talia, Wang, Julie, Johnson, Sarah, Brown, Matthew, Chiang, Meng-Jung, Dolan, Sherri, Breuning, Carl, Velugula-Yellela, Sai Rashmika, Lute, Scott, Fratz-Berilla, Erica J, Brorson, Kurt
Published in PDA journal of pharmaceutical science and technology (01.03.2020)
Published in PDA journal of pharmaceutical science and technology (01.03.2020)
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Journal Article
Differential effects of bioreactor process variables and purification on the human recombinant lysosomal enzyme [beta]-glucuronidase produced from Chinese hamster ovary cells
Parhiz, Hamideh, Ketcham, Stephanie A, Zou, Guozhang, Ghosh, Bidesh, Fratz-Berilla, Erica J, Ashraf, Muhammad, Ju, Tongzhong
Published in Applied microbiology and biotechnology (01.08.2019)
Published in Applied microbiology and biotechnology (01.08.2019)
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Journal Article
Primary Clarification of CHO Harvested Cell Culture Fluid using an Acoustic Separator
Hong, Jin Sung, Azer, Nicole, Agarabi, Cyrus, Fratz-Berilla, Erica J.
Published in Journal of visualized experiments (14.05.2020)
Published in Journal of visualized experiments (14.05.2020)
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Journal Article
Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System
Velugula-Yellela, Sai Rashmika, Powers, David N., Angart, Phillip, Faustino, Anneliese, Faison, Talia, Kohnhorst, Casey, Fratz-Berilla, Erica J., Agarabi, Cyrus D.
Published in Journal of visualized experiments (01.05.2019)
Published in Journal of visualized experiments (01.05.2019)
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Journal Article