Left frontal cortex connectivity underlies cognitive reserve in prodromal Alzheimer disease
Franzmeier, Nicolai, Duering, Marco, Weiner, Michael, Dichgans, Martin, Ewers, Michael
Published in Neurology (14.03.2017)
Published in Neurology (14.03.2017)
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Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance
Stern, Yaakov, Arenaza-Urquijo, Eider M., Bartrés-Faz, David, Belleville, Sylvie, Cantilon, Marc, Chetelat, Gael, Ewers, Michael, Franzmeier, Nicolai, Kempermann, Gerd, Kremen, William S., Okonkwo, Ozioma, Scarmeas, Nikolaos, Soldan, Anja, Udeh-Momoh, Chinedu, Valenzuela, Michael, Vemuri, Prashanthi, Vuoksimaa, Eero, Arenaza Urquiljo, Eider M., Bartrés-Faz, David, Belleville, Sylvie, Cantillon, Marc, Chetelat, Gael, Clouston, Sean A.P., Estanga, Ainara, Ewers, Michael, Franzmeier, Nicolai, Gold, Brian, Habeck, Christian, Jones, Richard, Kempermann, Gerd, Kochhann, Renata, Kremen, William, Lim, Yen Ying, Martínez-Lage, Pablo, Morbelli, Silvia, Okonkwo, Ozioma, Ossenkoppele, Rik, Pettigrew, Corinne, Rosen, Allyson C., Scarmeas, Nikolaos, Soldan, Anja, Song, Xiaowei, Udeh-Momoh, Chinedu, Stern, Yaakov, Valenzuela, Michael, Van Loenhoud, Anita C., Vemuri, Prashanthi, Vuoksimaa, Eero
Published in Alzheimer's & dementia (01.09.2020)
Published in Alzheimer's & dementia (01.09.2020)
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Tau-PET and in vivo Braak-staging as prognostic markers of future cognitive decline in cognitively normal to demented individuals
Biel, Davina, Brendel, Matthias, Rubinski, Anna, Buerger, Katharina, Janowitz, Daniel, Dichgans, Martin, Franzmeier, Nicolai
Published in Alzheimer's research & therapy (12.08.2021)
Published in Alzheimer's research & therapy (12.08.2021)
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Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology
Suárez-Calvet, Marc, Morenas-Rodríguez, Estrella, Kleinberger, Gernot, Schlepckow, Kai, Araque Caballero, Miguel Ángel, Franzmeier, Nicolai, Capell, Anja, Fellerer, Katrin, Nuscher, Brigitte, Eren, Erden, Levin, Johannes, Deming, Yuetiva, Piccio, Laura, Karch, Celeste M, Cruchaga, Carlos, Shaw, Leslie M, Trojanowski, John Q, Weiner, Michael, Ewers, Michael, Haass, Christian
Published in Molecular neurodegeneration (10.01.2019)
Published in Molecular neurodegeneration (10.01.2019)
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White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease
Araque Caballero, Miguel Ángel, Suárez-Calvet, Marc, Duering, Marco, Franzmeier, Nicolai, Benzinger, Tammie, Fagan, Anne M, Bateman, Randall J, Jack, Clifford R, Levin, Johannes, Dichgans, Martin, Jucker, Mathias, Karch, Celeste, Masters, Colin L, Morris, John C, Weiner, Michael, Rossor, Martin, Fox, Nick C, Lee, Jae-Hong, Salloway, Stephen, Danek, Adrian, Goate, Alison, Yakushev, Igor, Hassenstab, Jason, Schofield, Peter R, Haass, Christian, Ewers, Michael
Published in Brain (London, England : 1878) (01.10.2018)
Published in Brain (London, England : 1878) (01.10.2018)
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Tau deposition patterns are associated with functional connectivity in primary tauopathies
Franzmeier, Nicolai, Brendel, Matthias, Beyer, Leonie, Slemann, Luna, Kovacs, Gabor G., Arzberger, Thomas, Kurz, Carolin, Respondek, Gesine, Lukic, Milica J., Biel, Davina, Rubinski, Anna, Frontzkowski, Lukas, Hummel, Selina, Müller, Andre, Finze, Anika, Palleis, Carla, Joseph, Emanuel, Weidinger, Endy, Katzdobler, Sabrina, Song, Mengmeng, Biechele, Gloria, Kern, Maike, Scheifele, Maximilian, Rauchmann, Boris-Stephan, Perneczky, Robert, Rullman, Michael, Patt, Marianne, Schildan, Andreas, Barthel, Henryk, Sabri, Osama, Rumpf, Jost J., Schroeter, Matthias L., Classen, Joseph, Villemagne, Victor, Seibyl, John, Stephens, Andrew W., Lee, Edward B., Coughlin, David G., Giese, Armin, Grossman, Murray, McMillan, Corey T., Gelpi, Ellen, Molina-Porcel, Laura, Compta, Yaroslau, van Swieten, John C., Laat, Laura Donker, Troakes, Claire, Al-Sarraj, Safa, Robinson, John L., Xie, Sharon X., Irwin, David J., Roeber, Sigrun, Herms, Jochen, Simons, Mikael, Bartenstein, Peter, Lee, Virginia M., Trojanowski, John Q., Levin, Johannes, Höglinger, Günter, Ewers, Michael
Published in Nature communications (15.03.2022)
Published in Nature communications (15.03.2022)
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Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading
Frontzkowski, Lukas, Ewers, Michael, Brendel, Matthias, Biel, Davina, Ossenkoppele, Rik, Hager, Paul, Steward, Anna, Dewenter, Anna, Römer, Sebastian, Rubinski, Anna, Buerger, Katharina, Janowitz, Daniel, Binette, Alexa Pichet, Smith, Ruben, Strandberg, Olof, Carlgren, Niklas Mattsson, Dichgans, Martin, Hansson, Oskar, Franzmeier, Nicolai
Published in Nature communications (20.08.2022)
Published in Nature communications (20.08.2022)
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Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation
Ewers, Michael, Biechele, Gloria, Suárez‐Calvet, Marc, Sacher, Christian, Blume, Tanja, Morenas‐Rodriguez, Estrella, Deming, Yuetiva, Piccio, Laura, Cruchaga, Carlos, Kleinberger, Gernot, Shaw, Leslie, Trojanowski, John Q, Herms, Jochen, Dichgans, Martin, Brendel, Matthias, Haass, Christian, Franzmeier, Nicolai
Published in EMBO molecular medicine (07.09.2020)
Published in EMBO molecular medicine (07.09.2020)
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Free water determines diffusion alterations and clinical status in cerebral small vessel disease
Duering, Marco, Finsterwalder, Sofia, Baykara, Ebru, Tuladhar, Anil Man, Gesierich, Benno, Konieczny, Marek J., Malik, Rainer, Franzmeier, Nicolai, Ewers, Michael, Jouvent, Eric, Biessels, Geert Jan, Schmidt, Reinhold, de Leeuw, Frank-Erik, Pasternak, Ofer, Dichgans, Martin
Published in Alzheimer's & dementia (01.06.2018)
Published in Alzheimer's & dementia (01.06.2018)
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The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer’s disease
Franzmeier, Nicolai, Ren, Jinyi, Damm, Alexander, Monté-Rubio, Gemma, Boada, Mercè, Ruiz, Agustín, Ramirez, Alfredo, Jessen, Frank, Düzel, Emrah, Rodríguez Gómez, Octavio, Benzinger, Tammie, Goate, Alison, Karch, Celeste M., Fagan, Anne M., McDade, Eric, Buerger, Katharina, Levin, Johannes, Duering, Marco, Dichgans, Martin, Suárez-Calvet, Marc, Haass, Christian, Gordon, Brian A., Lim, Yen Ying, Masters, Colin L., Janowitz, Daniel, Catak, Cihan, Wolfsgruber, Steffen, Wagner, Michael, Milz, Esther, Moreno-Grau, Sonia, Teipel, Stefan, Grothe, Michel J, Kilimann, Ingo, Rossor, Martin, Fox, Nick, Laske, Christoph, Chhatwal, Jasmeer, Falkai, Peter, Perneczky, Robert, Lee, Jae-Hong, Spottke, Annika, Boecker, Henning, Brosseron, Frederic, Fliessbach, Klaus, Heneka, Michael T., Nestor, Peter, Peters, Oliver, Fuentes, Manuel, Menne, Felix, Priller, Josef, Spruth, Eike J., Franke, Christiana, Schneider, Anja, Westerteicher, Christine, Speck, Oliver, Wiltfang, Jens, Bartels, Claudia, Araque Caballero, Miguel Ángel, Metzger, Coraline, Bittner, Daniel, Salloway, Stephen, Danek, Adrian, Hassenstab, Jason, Yakushev, Igor, Schofield, Peter R., Morris, John C., Bateman, Randall J., Ewers, Michael
Published in Molecular psychiatry (01.02.2021)
Published in Molecular psychiatry (01.02.2021)
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Journal Article
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease
Franzmeier, Nicolai, Düzel, Emrah, Jessen, Frank, Buerger, Katharina, Levin, Johannes, Duering, Marco, Dichgans, Martin, Haass, Christian, Suárez-Calvet, Marc, Fagan, Anne M, Paumier, Katrina, Benzinger, Tammie, Masters, Colin L, Morris, John C, Perneczky, Robert, Janowitz, Daniel, Catak, Cihan, Wolfsgruber, Steffen, Wagner, Michael, Teipel, Stefan, Kilimann, Ingo, Ramirez, Alfredo, Rossor, Martin, Jucker, Mathias, Chhatwal, Jasmeer, Spottke, Annika, Boecker, Henning, Brosseron, Frederic, Falkai, Peter, Fliessbach, Klaus, Heneka, Michael T, Laske, Christoph, Nestor, Peter, Peters, Oliver, Fuentes, Manuel, Menne, Felix, Priller, Josef, Spruth, Eike J, Franke, Christiana, Schneider, Anja, Kofler, Barbara, Westerteicher, Christine, Speck, Oliver, Wiltfang, Jens, Bartels, Claudia, Araque Caballero, Miguel Ángel, Metzger, Coraline, Bittner, Daniel, Weiner, Michael, Lee, Jae-Hong, Salloway, Stephen, Danek, Adrian, Goate, Alison, Schofield, Peter R, Bateman, Randall J, Ewers, Michael
Published in Brain (London, England : 1878) (01.04.2018)
Published in Brain (London, England : 1878) (01.04.2018)
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Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease
Franzmeier, Nicolai, Dewenter, Anna, Frontzkowski, Lukas, Dichgans, Martin, Rubinski, Anna, Neitzel, Julia, Smith, Ruben, Strandberg, Olof, Ossenkoppele, Rik, Buerger, Katharina, Duering, Marco, Hansson, Oskar, Ewers, Michael
Published in Science advances (27.11.2020)
Published in Science advances (27.11.2020)
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Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer’s disease
Franzmeier, Nicolai, Dehsarvi, Amir, Steward, Anna, Biel, Davina, Dewenter, Anna, Roemer, Sebastian Niclas, Wagner, Fabian, Groß, Mattes, Brendel, Matthias, Moscoso, Alexis, Arunachalam, Prithvi, Blennow, Kaj, Zetterberg, Henrik, Ewers, Michael, Schöll, Michael
Published in Nature communications (03.01.2024)
Published in Nature communications (03.01.2024)
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Towards multicenter β-amyloid PET imaging in mouse models: A triple scanner head-to-head comparison
Gnörich, Johannes, Koehler, Mara, Wind-Mark, Karin, Klaus, Carolin, Zatcepin, Artem, Palumbo, Giovanna, Lalia, Manvir, Monasor, Laura Sebastian, Beyer, Leonie, Eckenweber, Florian, Scheifele, Maximilian, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Barthel, Henryk, Sabri, Osama, Bartenstein, Peter, Herms, Jochen, Tahirovic, Sabina, Franzmeier, Nicolai, Ziegler, Sibylle, Brendel, Matthias
Published in NeuroImage (Orlando, Fla.) (15.08.2024)
Published in NeuroImage (Orlando, Fla.) (15.08.2024)
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CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline
Suárez‐Calvet, Marc, Capell, Anja, Araque Caballero, Miguel Ángel, Morenas‐Rodríguez, Estrella, Fellerer, Katrin, Franzmeier, Nicolai, Kleinberger, Gernot, Eren, Erden, Deming, Yuetiva, Piccio, Laura, Karch, Celeste M, Cruchaga, Carlos, Paumier, Katrina, Bateman, Randall J, Fagan, Anne M, Morris, John C, Levin, Johannes, Danek, Adrian, Jucker, Mathias, Masters, Colin L, Rossor, Martin N, Ringman, John M, Shaw, Leslie M, Trojanowski, John Q, Weiner, Michael, Ewers, Michael, Haass, Christian
Published in EMBO molecular medicine (01.12.2018)
Published in EMBO molecular medicine (01.12.2018)
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sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's disease
Biel, Davina, Suárez‐Calvet, Marc, Hager, Paul, Rubinski, Anna, Dewenter, Anna, Steward, Anna, Roemer, Sebastian, Ewers, Michael, Haass, Christian, Brendel, Matthias, Franzmeier, Nicolai
Published in EMBO molecular medicine (08.02.2023)
Published in EMBO molecular medicine (08.02.2023)
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Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases
Biechele, Gloria, Franzmeier, Nicolai, Blume, Tanja, Ewers, Michael, Luque, Jose Medina, Eckenweber, Florian, Sacher, Christian, Beyer, Leonie, Ruch-Rubinstein, Francois, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Cumming, Paul, Bartenstein, Peter, Rominger, Axel, Höglinger, Günter U, Herms, Jochen, Brendel, Matthias
Published in Journal of neuroinflammation (14.12.2020)
Published in Journal of neuroinflammation (14.12.2020)
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Resting-State Connectivity of the Left Frontal Cortex to the Default Mode and Dorsal Attention Network Supports Reserve in Mild Cognitive Impairment
Franzmeier, Nicolai, Göttler, Jens, Grimmer, Timo, Drzezga, Alexander, Áraque-Caballero, Miguel A, Simon-Vermot, Lee, Taylor, Alexander N W, Bürger, Katharina, Catak, Cihan, Janowitz, Daniel, Müller, Claudia, Duering, Marco, Sorg, Christian, Ewers, Michael
Published in Frontiers in aging neuroscience (07.08.2017)
Published in Frontiers in aging neuroscience (07.08.2017)
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Associations between sex, body mass index and the individual microglial response in Alzheimer's disease
Biechele, Gloria, Rauchmann, Boris-Stephan, Janowitz, Daniel, Buerger, Katharina, Franzmeier, Nicolai, Weidinger, Endy, Guersel, Selim, Schuster, Sebastian, Finze, Anika, Harris, Stefanie, Lindner, Simon, Albert, Nathalie L, Wetzel, Christian, Rupprecht, Rainer, Rominger, Axel, Palleis, Carla, Katzdobler, Sabrina, Burow, Lena, Kurz, Carolin, Zaganjori, Mirlind, Trappmann, Lena-Katharina, Goldhardt, Oliver, Grimmer, Timo, Haeckert, Jan, Keeser, Daniel, Stoecklein, Sophia, Morenas-Rodriguez, Estrella, Bartenstein, Peter, Levin, Johannes, Höglinger, Günter U, Simons, Mikael, Perneczky, Robert, Brendel, Matthias
Published in Journal of neuroinflammation (23.01.2024)
Published in Journal of neuroinflammation (23.01.2024)
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