Extracellular vesicles and nanoparticles: emerging complexities
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Published in Trends in cell biology (01.08.2023)
Published in Trends in cell biology (01.08.2023)
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The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
Powell, Anne E., Wang, Yang, Li, Yina, Poulin, Emily J., Means, Anna L., Washington, Mary K., Higginbotham, James N., Juchheim, Alwin, Prasad, Nripesh, Levy, Shawn E., Guo, Yan, Shyr, Yu, Aronow, Bruce J., Haigis, Kevin M., Franklin, Jeffrey L., Coffey, Robert J.
Published in Cell (30.03.2012)
Published in Cell (30.03.2012)
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Comprehensive isolation of extracellular vesicles and nanoparticles
Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Franklin, Jeffrey L., Coffey, Robert J.
Published in Nature protocols (01.05.2023)
Published in Nature protocols (01.05.2023)
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Reassessment of Exosome Composition
Jeppesen, Dennis K., Fenix, Aidan M., Franklin, Jeffrey L., Higginbotham, James N., Zhang, Qin, Zimmerman, Lisa J., Liebler, Daniel C., Ping, Jie, Liu, Qi, Evans, Rachel, Fissell, William H., Patton, James G., Rome, Leonard H., Burnette, Dylan T., Coffey, Robert J.
Published in Cell (04.04.2019)
Published in Cell (04.04.2019)
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Amphiregulin Exosomes Increase Cancer Cell Invasion
Higginbotham, James N., Demory Beckler, Michelle, Gephart, Jonathan D., Franklin, Jeffrey L., Bogatcheva, Galina, Kremers, Gert-Jan, Piston, David W., Ayers, Gregory D., McConnell, Russell E., Tyska, Matthew J., Coffey, Robert J.
Published in Current biology (10.05.2011)
Published in Current biology (10.05.2011)
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KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes
McKenzie, Andrew J., Hoshino, Daisuke, Hong, Nan Hyung, Cha, Diana J., Franklin, Jeffrey L., Coffey, Robert J., Patton, James G., Weaver, Alissa M.
Published in Cell reports (Cambridge) (03.05.2016)
Published in Cell reports (Cambridge) (03.05.2016)
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Transfer of Functional Cargo in Exomeres
Zhang, Qin, Higginbotham, James N., Jeppesen, Dennis K., Yang, Yu-Ping, Li, Wei, McKinley, Eliot T., Graves-Deal, Ramona, Ping, Jie, Britain, Colleen M., Dorsett, Kaitlyn A., Hartman, Celine L., Ford, David A., Allen, Ryan M., Vickers, Kasey C., Liu, Qi, Franklin, Jeffrey L., Bellis, Susan L., Coffey, Robert J.
Published in Cell reports (Cambridge) (16.04.2019)
Published in Cell reports (Cambridge) (16.04.2019)
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lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling
Lu, Yuanyuan, Zhao, Xiaodi, Liu, Qi, Li, Cunxi, Graves-Deal, Ramona, Cao, Zheng, Singh, Bhuminder, Franklin, Jeffrey L, Wang, Jing, Hu, Huaying, Wei, Tianying, Yang, Mingli, Yeatman, Timothy J, Lee, Ethan, Saito-Diaz, Kenyi, Hinger, Scott, Patton, James G, Chung, Christine H, Emmrich, Stephan, Klusmann, Jan-Henning, Fan, Daiming, Coffey, Robert J
Published in Nature medicine (01.11.2017)
Published in Nature medicine (01.11.2017)
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Proteomic Analysis of Exosomes from Mutant KRAS Colon Cancer Cells Identifies Intercellular Transfer of Mutant KRAS
Demory Beckler, Michelle, Higginbotham, James N., Franklin, Jeffrey L., Ham, Amy-Joan, Halvey, Patrick J., Imasuen, Imade E., Whitwell, Corbin, Li, Ming, Liebler, Daniel C., Coffey, Robert J.
Published in Molecular & cellular proteomics (01.02.2013)
Published in Molecular & cellular proteomics (01.02.2013)
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Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes
Dou, Yongchao, Cha, Diana J., Franklin, Jeffrey L., Higginbotham, James N., Jeppesen, Dennis K., Weaver, Alissa M., Prasad, Nripesh, Levy, Shawn, Coffey, Robert J., Patton, James G., Zhang, Bing
Published in Scientific reports (28.11.2016)
Published in Scientific reports (28.11.2016)
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Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Graves-Deal, Ramona, Trinh, Vincent Q., Ramirez, Marisol A., Sohn, Yoojin, Neininger, Abigail C., Taneja, Nilay, McKinley, Eliot T., Niitsu, Hiroaki, Cao, Zheng, Evans, Rachel, Glass, Sarah E., Ray, Kevin C., Fissell, William H., Hill, Salisha, Rose, Kristie Lindsey, Huh, Won Jae, Washington, Mary Kay, Ayers, Gregory Daniel, Burnette, Dylan T., Sharma, Shivani, Rome, Leonard H., Franklin, Jeffrey L., Lee, Youngmin A., Liu, Qi, Coffey, Robert J.
Published in Nature cell biology (01.12.2021)
Published in Nature cell biology (01.12.2021)
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Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression
Liu, Hao, Li, Danxiu, Sun, Lina, Qin, Hongqiang, Fan, Ahui, Meng, Lingnan, Graves-Deal, Ramona, Glass, Sarah E, Franklin, Jeffrey L, Liu, Qi, Wang, Jing, Yeatman, Timothy J, Guo, Hao, Zong, Hong, Jin, Shuilin, Chen, Zhiyu, Deng, Ting, Fang, Ying, Li, Cunxi, Karijolich, John, Patton, James G, Wang, Xin, Nie, Yongzhan, Fan, Daiming, Coffey, Robert J, Zhao, Xiaodi, Lu, Yuanyuan
Published in Molecular cancer (12.03.2022)
Published in Molecular cancer (12.03.2022)
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Quantitative Proteomic Analysis of Small and Large Extracellular Vesicles (EVs) Reveals Enrichment of Adhesion Proteins in Small EVs
Jimenez, Lizandra, Yu, Hui, McKenzie, Andrew J, Franklin, Jeffrey L, Patton, James G, Liu, Qi, Weaver, Alissa M
Published in Journal of proteome research (01.03.2019)
Published in Journal of proteome research (01.03.2019)
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KRAS-dependent sorting of miRNA to exosomes
Cha, Diana J, Franklin, Jeffrey L, Dou, Yongchao, Liu, Qi, Higginbotham, James N, Demory Beckler, Michelle, Weaver, Alissa M, Vickers, Kasey, Prasad, Nirpesh, Levy, Shawn, Zhang, Bing, Coffey, Robert J, Patton, James G
Published in eLife (01.07.2015)
Published in eLife (01.07.2015)
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Angiotensin-converting Enzyme 2–containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein
Zhang, Qin, Jeppesen, Dennis K., Higginbotham, James N., Franklin, Jeffrey L., Crowe, James E., Coffey, Robert J.
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2021)
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Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism
Chumbler, Nicole M, Farrow, Melissa A, Lapierre, Lynne A, Franklin, Jeffrey L, Haslam, David B, Haslam, David, Goldenring, James R, Lacy, D Borden
Published in PLoS pathogens (01.12.2012)
Published in PLoS pathogens (01.12.2012)
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Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells
Hinger, Scott A., Cha, Diana J., Franklin, Jeffrey L., Higginbotham, James N., Dou, Yongchao, Ping, Jie, Shu, Lihua, Prasad, Nripesh, Levy, Shawn, Zhang, Bing, Liu, Qi, Weaver, Alissa M., Coffey, Robert J., Patton, James G.
Published in Cell reports (Cambridge) (16.10.2018)
Published in Cell reports (Cambridge) (16.10.2018)
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A smooth muscle‐derived, Braf‐driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell‐of‐origin
Kondo, Jumpei, Huh, Won Jae, Franklin, Jeffrey L, Heinrich, Michael C, Rubin, Brian P, Coffey, Robert J
Published in The Journal of pathology (01.12.2020)
Published in The Journal of pathology (01.12.2020)
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Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex
Farrow, Melissa A., Chumbler, Nicole M., Lapierre, Lynne A., Franklin, Jeffrey L., Rutherford, Stacey A., Goldenring, James R., Lacy, D. Borden
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2013)
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Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells
Hinger, Scott A., Abner, Jessica J., Franklin, Jeffrey L., Jeppesen, Dennis K., Coffey, Robert J., Patton, James G.
Published in Scientific reports (25.09.2020)
Published in Scientific reports (25.09.2020)
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