Preclinical Assessment of the Analgesic Pharmacology of NKTR-181 in Rodents
Kopruszinski, Caroline M., Swiokla, Juliana, Lee, Yeon Sun, Navratilova, Edita, VanderVeen, Laurie, Yang, Miao, Liu, Yi, Miyazaki, Takahiro, Schmidt, William K., Zalevsky, Jonathan, Porreca, Frank
Published in Cellular and molecular neurobiology (01.07.2021)
Published in Cellular and molecular neurobiology (01.07.2021)
Get full text
Journal Article
Inhibition of experimental visceral pain in rodents by cebranopadol
Schiene, Klaus, Schröder, Wolfgang, Linz, Klaus, Frosch, Stefanie, Tzschentke, Thomas M, Christoph, Thomas, Xie, Jennifer Y, Porreca, Frank
Published in Behavioural pharmacology (01.06.2019)
Published in Behavioural pharmacology (01.06.2019)
Get more information
Journal Article
The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced l-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia
Flores, Andrew J., Bartlett, Mitchell J., Root, Brandon K., Parent, Kate L., Heien, Michael L., Porreca, Frank, Polt, Robin, Sherman, Scott J., Falk, Torsten
Published in Neuropharmacology (01.10.2018)
Published in Neuropharmacology (01.10.2018)
Get full text
Journal Article
Design, synthesis and biological evaluation of multifunctional ligands targeting opioid and bradykinin 2 receptors
Deekonda, Srinivas, Rankin, David, Davis, Peg, Lai, Josephine, Porreca, Frank, Hruby, Victor J.
Published in Bioorganic & medicinal chemistry letters (01.10.2015)
Published in Bioorganic & medicinal chemistry letters (01.10.2015)
Get full text
Journal Article
Triptan-induced enhancement of neuronal nitric oxide synthase in trigeminal ganglion dural afferents underlies increased responsiveness to potential migraine triggers
De Felice, Milena, Ossipov, Michael H., Wang, Ruizhong, Dussor, Gregory, Lai, Josephine, Meng, Ian D., Chichorro, Juliana, Andrews, John S., Rakhit, Suman, Maddaford, Shawn, Dodick, David, Porreca, Frank
Published in Brain (London, England : 1878) (01.08.2010)
Published in Brain (London, England : 1878) (01.08.2010)
Get full text
Journal Article
Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-E 2 in the spinal cord
Marshall, Timothy M., Herman, David S., Largent-Milnes, Tally M., Badghisi, Hamid, Zuber, Konstantina, Holt, Shannon C., Lai, Josephine, Porreca, Frank, Vanderah, Todd W.
Published in Pain (Amsterdam) (2012)
Published in Pain (Amsterdam) (2012)
Get full text
Journal Article
Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential
Xie, Jennifer Y, Chew, Lindsey A, Yang, Xiaofang, Wang, Yuying, Qu, Chaoling, Wang, Yue, Federici, Lauren M, Fitz, Stephanie D, Ripsch, Matthew S, Due, Michael R, Moutal, Aubin, Khanna, May, White, Fletcher A, Vanderah, Todd W, Johnson, Philip L, Porreca, Frank, Khanna, Rajesh
Published in Pain (Amsterdam) (01.09.2016)
Published in Pain (Amsterdam) (01.09.2016)
Get full text
Journal Article
Spinal GABA(A) and GABA(B) receptor pharmacology in a rat model of neuropathic pain
Malan, T Philip, Mata, Heriberto P, Porreca, Frank
Published in Anesthesiology (Philadelphia) (01.05.2002)
Published in Anesthesiology (Philadelphia) (01.05.2002)
Get full text
Journal Article
Positive allosteric modulators of nonbenzodiazepine γ-aminobutyric acidA receptor subtypes for the treatment of chronic pain
Johnstone, Timothy B C, Xie, Jennifer Y, Qu, Chaoling, Wasiak, David J, Hogenkamp, Derk J, Porreca, Frank, Gee, Kelvin W
Published in Pain (Amsterdam) (01.01.2019)
Published in Pain (Amsterdam) (01.01.2019)
Get full text
Journal Article
Antinociceptive and nociceptive actions of opioids
Ossipov, Michael H, Lai, Josephine, King, Tamara, Vanderah, Todd W, Malan, Jr, T Philip, Hruby, Victor J, Porreca, Frank
Published in Journal of neurobiology (01.10.2004)
Published in Journal of neurobiology (01.10.2004)
Get more information
Journal Article
Erratum to ‛Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light
Khanna, Rajesh, Patwardhan, Amol, Yang, Xiaofang, Li, Wennan, Cai, Song, Ji, Yingshi, Chew, Lindsey A., Dorame, Angie, Bellampalli, Shreya S., Schmoll, Ryan W., Gordon, Janalee, Moutal, Aubin, Vanderah, Todd W., Porreca, Frank, Ibrahim, Mohab M.
Published in The journal of pain (01.12.2019)
Published in The journal of pain (01.12.2019)
Get full text
Journal Article
Redistribution of Na(V)1.8 in uninjured axons enables neuropathic pain
Gold, Michael S, Weinreich, Daniel, Kim, Chang-Sook, Wang, Ruizhong, Treanor, James, Porreca, Frank, Lai, Josephine
Published in The Journal of neuroscience (01.01.2003)
Get full text
Published in The Journal of neuroscience (01.01.2003)
Journal Article
Cyclic non-opioid dynorphin A analogues for the bradykinin receptors
Lee, Yeon Sun, Remesic, Michael, Ramos-Colon, Cyf, Hall, Sara M., Kuzmin, Alexander, Rankin, David, Porreca, Frank, Lai, Josephine, Hruby, Victor J.
Published in Bioorganic & medicinal chemistry letters (15.11.2016)
Published in Bioorganic & medicinal chemistry letters (15.11.2016)
Get full text
Journal Article
Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway
Little, Joshua W, Chen, Zhoumou, Doyle, Timothy, Porreca, Frank, Ghaffari, Mahsa, Bryant, Leesa, Neumann, William L, Salvemini, Daniela
Published in The Journal of neuroscience (08.08.2012)
Published in The Journal of neuroscience (08.08.2012)
Get full text
Journal Article
The cis-4-Amino-l-proline Residue as a Scaffold for the Synthesis of Cyclic and Linear Endomorphin-2 Analogues
Mollica, Adriano, Pinnen, Francesco, Stefanucci, Azzurra, Feliciani, Federica, Campestre, Cristina, Mannina, Luisa, Sobolev, Anatoly P, Lucente, Gino, Davis, Peg, Lai, Josephine, Ma, Shou-Wu, Porreca, Frank, Hruby, Victor J
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
Get full text
Journal Article
Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist – Neurokinin-1 antagonist peptidomimetics
Guillemyn, Karel, Kleczkowska, Patrycia, Lesniak, Anna, Dyniewicz, Jolanta, Van der Poorten, Olivier, Van den Eynde, Isabelle, Keresztes, Attila, Varga, Eva, Lai, Josephine, Porreca, Frank, Chung, Nga N., Lemieux, Carole, Mika, Joanna, Rojewska, Ewelina, Makuch, Wioletta, Van Duppen, Joost, Przewlocka, Barbara, Vanden Broeck, Jozef, Lipkowski, Andrzej W., Schiller, Peter W., Tourwé, Dirk, Ballet, Steven
Published in European journal of medicinal chemistry (06.03.2015)
Published in European journal of medicinal chemistry (06.03.2015)
Get full text
Journal Article