Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase
Fang, Pengfei, Yu, Xue, Jeong, Seung Jae, Mirando, Adam, Chen, Kaige, Chen, Xin, Kim, Sunghoon, Francklyn, Christopher S, Guo, Min
Published in Nature communications (31.03.2015)
Published in Nature communications (31.03.2015)
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Neuropathy‐associated histidyl‐tRNA synthetase variants attenuate protein synthesis in vitro and disrupt axon outgrowth in developing zebrafish
Mullen, Patrick, Abbott, Jamie A., Wellman, Theresa, Aktar, Mahafuza, Fjeld, Christian, Demeler, Borries, Ebert, Alicia M., Francklyn, Christopher S.
Published in The FEBS journal (01.01.2021)
Published in The FEBS journal (01.01.2021)
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Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo
Novoa, Eva Maria, Camacho, Noelia, Tor, Anna, Wilkinson, Barrie, Moss, Steven, Marín-García, Patricia, Azcárate, Isabel G., Bautista, José M., Mirando, Adam C., Francklyn, Christopher S., Varon, Sònia, Royo, Miriam, Cortés, Alfred, Ribas de Pouplana, Lluís
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2014)
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Journal Article
Regulation of angiogenesis by aminoacyl-tRNA synthetases
Mirando, Adam C, Francklyn, Christopher S, Lounsbury, Karen M
Published in International Journal of Molecular Sciences (19.12.2014)
Published in International Journal of Molecular Sciences (19.12.2014)
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Book Review
Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor
Mirando, Adam C, Fang, Pengfei, Williams, Tamara F, Baldor, Linda C, Howe, Alan K, Ebert, Alicia M, Wilkinson, Barrie, Lounsbury, Karen M, Guo, Min, Francklyn, Christopher S
Published in Scientific reports (14.08.2015)
Published in Scientific reports (14.08.2015)
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Journal Article
A Substrate-Assisted Concerted Mechanism for Aminoacylation by a Class II Aminoacyl-tRNA Synthetase
Guth, Ethan, Connolly, Susan H, Bovee, Michael, Francklyn, Christopher S
Published in Biochemistry (Easton) (15.03.2005)
Published in Biochemistry (Easton) (15.03.2005)
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Substrate Recognition by the Hetero-Octameric ATP Phosphoribosyltransferase from Lactococcus lactis
Champagne, Karen S, Piscitelli, Elise, Francklyn, Christopher S
Published in Biochemistry (Easton) (19.12.2006)
Published in Biochemistry (Easton) (19.12.2006)
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Journal Article
Aminoacyl Transfer Rate Dictates Choice of Editing Pathway in Threonyl-tRNA Synthetase
Minajigi, Anand, Francklyn, Christopher S.
Published in The Journal of biological chemistry (30.07.2010)
Published in The Journal of biological chemistry (30.07.2010)
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Transfer RNA and human disease
Abbott, Jamie A, Francklyn, Christopher S, Robey-Bond, Susan M
Published in Frontiers in genetics (03.06.2014)
Published in Frontiers in genetics (03.06.2014)
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Standardizing Analysis of Circulating MicroRNA: Clinical and Biological Relevance
Farina, Nicholas H., Wood, Marie E., Perrapato, Scott D., Francklyn, Christopher S., Stein, Gary S., Stein, Janet L., Lian, Jane B.
Published in Journal of cellular biochemistry (01.05.2014)
Published in Journal of cellular biochemistry (01.05.2014)
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