novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells
Massey, Andrew J, Williamson, Douglas S, Browne, Helen, Murray, James B, Dokurno, Pawel, Shaw, Terry, Macias, Alba T, Daniels, Zoe, Geoffroy, Stephanie, Dopson, Melanie, Lavan, Paul, Matassova, Natalia, Francis, Geraint L, Graham, Christopher J, Parsons, Rachel, Wang, Yikang, Padfield, Antony, Comer, Mike, Drysdale, Martin J, Wood, Mike
Published in Cancer chemotherapy and pharmacology (01.08.2010)
Published in Cancer chemotherapy and pharmacology (01.08.2010)
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Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design
Williamson, Douglas S, Borgognoni, Jenifer, Clay, Alexandra, Daniels, Zoe, Dokurno, Pawel, Drysdale, Martin J, Foloppe, Nicolas, Francis, Geraint L, Graham, Christopher J, Howes, Rob, Macias, Alba T, Murray, James B, Parsons, Rachel, Shaw, Terry, Surgenor, Allan E, Terry, Lindsey, Wang, Yikang, Wood, Mike, Massey, Andrew J
Published in Journal of medicinal chemistry (26.03.2009)
Published in Journal of medicinal chemistry (26.03.2009)
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Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity
Macias, Alba T, Williamson, Douglas S, Allen, Nicola, Borgognoni, Jenifer, Clay, Alexandra, Daniels, Zoe, Dokurno, Pawel, Drysdale, Martin J, Francis, Geraint L, Graham, Christopher J, Howes, Rob, Matassova, Natalia, Murray, James B, Parsons, Rachel, Shaw, Terry, Surgenor, Allan E, Terry, Lindsey, Wang, Yikang, Wood, Mike, Massey, Andrew J
Published in Journal of medicinal chemistry (23.06.2011)
Published in Journal of medicinal chemistry (23.06.2011)
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Triazolo[1,5- a]pyrimidines as novel CDK2 inhibitors: Protein structure-guided design and SAR
Richardson, Christine M., Williamson, Douglas S., Parratt, Martin J., Borgognoni, Jenifer, Cansfield, Andrew D., Dokurno, Pawel, Francis, Geraint L., Howes, Rob, Moore, Jonathan D., Murray, James B., Robertson, Alan, Surgenor, Allan E., Torrance, Christopher J.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Structure-guided design of pyrazolo[1,5- a]pyrimidines as inhibitors of human cyclin-dependent kinase 2
Williamson, Douglas S., Parratt, Martin J., Bower, Justin F., Moore, Jonathan D., Richardson, Christine M., Dokurno, Pawel, Cansfield, Andrew D., Francis, Geraint L., Hebdon, Richard J., Howes, Rob, Jackson, Philip S., Lockie, Andrea M., Murray, James B., Nunns, Claire L., Powles, Jenifer, Robertson, Alan, Surgenor, Allan E., Torrance, Christopher J.
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas
Hart, Terance, Macias, Alba T., Benwell, Karen, Brooks, Teresa, D’Alessandro, Jalanie, Dokurno, Pawel, Francis, Geraint, Gibbons, Ben, Haymes, Timothy, Kennett, Guy, Lightowler, Sean, Mansell, Howard, Matassova, Natalia, Misra, Anil, Padfield, Anthony, Parsons, Rachel, Pratt, Robert, Robertson, Alan, Walls, Steven, Wong, Melanie, Roughley, Stephen
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Fatty acid amide hydrolase inhibitors. 3: Tetra-substituted azetidine ureas with in vivo activity
Roughley, Stephen D., Browne, Helen, Macias, Alba T., Benwell, Karen, Brooks, Teresa, D’Alessandro, Jalanie, Daniels, Zoe, Dugdale, Sarah, Francis, Geraint, Gibbons, Ben, Hart, Terance, Haymes, Timothy, Kennett, Guy, Lightowler, Sean, Matassova, Natalia, Mansell, Howard, Merrett, Angela, Misra, Anil, Padfield, Anthony, Parsons, Rachel, Pratt, Robert, Robertson, Alan, Simmonite, Heather, Tan, Kiri, Walls, Steven B., Wong, Melanie
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Abstract A212: A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor-induced apoptosis in HCT116 colon carcinoma cells
Massey, Andrew J., Borgognoni, Jennifer, Browne, Helen, Daniels, Zoe, Dokurno, Pawel, Drysdale, Martin J., Francis, Geraint L., Graham, Christopher J., Macias, Alba T., Matassova, Natalia, Murray, James B., Parsons, Rachel, Shaw, Terry, Wang, Yikang, Wood, Mike, Williamson, Douglas
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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