Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy
Marciscano, Ariel E, Ghasemzadeh, Ali, Nirschl, Thomas R, Theodros, Debebe, Kochel, Christina M, Francica, Brian J, Muroyama, Yuki, Anders, Robert A, Sharabi, Andrew B, Velarde, Esteban, Mao, Wendy, Chaudhary, Kunal R, Chaimowitz, Matthew G, Wong, John, Selby, Mark J, Thudium, Kent B, Korman, Alan J, Ulmert, David, Thorek, Daniel L J, DeWeese, Theodore L, Drake, Charles G
Published in Clinical cancer research (15.10.2018)
Published in Clinical cancer research (15.10.2018)
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Stereotactic Radiation Therapy Augments Antigen-Specific PD-1-Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen
Sharabi, Andrew B, Nirschl, Christopher J, Kochel, Christina M, Nirschl, Thomas R, Francica, Brian J, Velarde, Esteban, Deweese, Theodore L, Drake, Charles G
Published in Cancer immunology research (01.04.2015)
Published in Cancer immunology research (01.04.2015)
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Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.
Published in Cell reports (Cambridge) (11.12.2018)
Published in Cell reports (Cambridge) (11.12.2018)
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Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens
Lynn, Geoffrey M., Sedlik, Christine, Baharom, Faezzah, Zhu, Yaling, Ramirez-Valdez, Ramiro A., Coble, Vincent L., Tobin, Kennedy, Nichols, Sarah R., Itzkowitz, Yaakov, Zaidi, Neeha, Gammon, Joshua M., Blobel, Nicolas J., Denizeau, Jordan, de la Rochere, Philippe, Francica, Brian J., Decker, Brennan, Maciejewski, Mateusz, Cheung, Justin, Yamane, Hidehiro, Smelkinson, Margery G., Francica, Joseph R., Laga, Richard, Bernstock, Joshua D., Seymour, Leonard W., Drake, Charles G., Jewell, Christopher M., Lantz, Olivier, Piaggio, Eliane, Ishizuka, Andrew S., Seder, Robert A.
Published in Nature biotechnology (01.03.2020)
Published in Nature biotechnology (01.03.2020)
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Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians
Shook, David R, Wen, Jason W H, Rolo, Ana, O'Hanlon, Michael, Francica, Brian, Dobbins, Destiny, Skoglund, Paul, DeSimone, Douglas W, Winklbauer, Rudolf, Keller, Ray E
Published in eLife (11.04.2022)
Published in eLife (11.04.2022)
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Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination
Jackson, Christopher M, Kochel, Christina M, Nirschl, Christopher J, Durham, Nicholas M, Ruzevick, Jacob, Alme, Angela, Francica, Brian J, Elias, Jimmy, Daniels, Andrew, Dubensky, Jr, Thomas W, Lauer, Peter, Brockstedt, Dirk G, Baxi, Emily G, Calabresi, Peter A, Taube, Janis M, Pardo, Carlos A, Brem, Henry, Pardoll, Drew M, Lim, Michael, Drake, Charles G
Published in Clinical cancer research (01.03.2016)
Published in Clinical cancer research (01.03.2016)
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TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors
Francica, Brian J, Ghasemzadeh, Ali, Desbien, Anthony L, Theodros, Debebe, Sivick, Kelsey E, Reiner, Gabrielle L, Hix Glickman, Laura, Marciscano, Ariel E, Sharabi, Andrew B, Leong, Meredith L, McWhirter, Sarah M, Dubensky, Jr, Thomas W, Pardoll, Drew M, Drake, Charles G
Published in Cancer immunology research (01.04.2018)
Published in Cancer immunology research (01.04.2018)
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Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model
Shen, Ying-Chun, Ghasemzadeh, Ali, Kochel, Christina M., Nirschl, Thomas R., Francica, Brian J., Lopez-Bujanda, Zoila A., Carrera Haro, Maria A., Tam, Ada, Anders, Robert A., Selby, Mark J., Korman, Alan J., Drake, Charles G.
Published in Prostate cancer and prostatic diseases (01.04.2018)
Published in Prostate cancer and prostatic diseases (01.04.2018)
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Journal Article
Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity
Sivick, Kelsey E., Desbien, Anthony L., Glickman, Laura Hix, Reiner, Gabrielle L., Corrales, Leticia, Surh, Natalie H., Hudson, Thomas E., Vu, Uyen T., Francica, Brian J., Banda, Tamara, Katibah, George E., Kanne, David B., Leong, Justin J., Metchette, Ken, Bruml, Jacob R., Ndubaku, Chudi O., McKenna, Jeffrey M., Feng, Yan, Zheng, Lianxing, Bender, Steven L., Cho, Charles Y., Leong, Meredith L., van Elsas, Andrea, Dubensky, Thomas W., McWhirter, Sarah M.
Published in Cell reports (Cambridge) (15.10.2019)
Published in Cell reports (Cambridge) (15.10.2019)
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Dual Blockade of EP2 and EP4 Signaling is Required for Optimal Immune Activation and Antitumor Activity Against Prostaglandin-Expressing Tumors
Francica, Brian J, Holtz, Anja, Lopez, Justine, Freund, David, Chen, Austin, Wang, Dingzhi, Powell, David, Kipper, Franciele, Panigrahy, Dipak, Dubois, Raymond N, Whiting, Chan C, Prasit, Peppi, Dubensky, Thomas W
Published in Cancer research communications (01.08.2023)
Published in Cancer research communications (01.08.2023)
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850 Dual blockade of the EP2 and EP4 PGE2 receptors with TPST-1495 is an optimal approach for drugging the prostaglandin pathway
Francica, Brian, Lopez, Justine, Holtz, Anja, Freund, Dave, Wang, Dingzhi, Enstrom, Amanda, Whiting, Sam, Whiting, Chan, Dubensky, Thomas
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma
Patel, Mira A., Kim, Jennifer E., Theodros, Debebe, Tam, Ada, Velarde, Esteban, Kochel, Christina M., Francica, Brian, Nirschl, Thomas R., Ghasemzadeh, Ali, Mathios, Dimitrios, Harris-Bookman, Sarah, Jackson, Christopher C., Jackson, Christina, Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Coric, Vladimir, Selby, Mark, Brem, Henry, Drake, Charles G., Pardoll, Drew M., Lim, Michael
Published in Journal for immunotherapy of cancer (17.05.2016)
Published in Journal for immunotherapy of cancer (17.05.2016)
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Erratum to: Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma
Patel, Mira A., Kim, Jennifer E., Theodros, Debebe, Tam, Ada, Velarde, Esteban, Kochel, Christina M., Francica, Brian, Nirschl, Thomas R., Ghasemzadeh, Ali, Mathios, Dimitrios, Harris-Bookman, Sarah, Jackson, Christopher C., Jackson, Christina, Ye, Xiaobu, Tran, Phuoc T., Tyler, Betty, Coric, Vladimir, Selby, Mark, Brem, Henry, Drake, Charles G., Pardoll, Drew M., Lim, Michael
Published in Journal for immunotherapy of cancer (04.11.2016)
Published in Journal for immunotherapy of cancer (04.11.2016)
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Anti-IL-10-mediated Enhancement of Antitumor Efficacy of a Dendritic Cell-targeting MIP3α-gp100 Vaccine in the B16F10 Mouse Melanoma Model Is Dependent on Type I Interferons
Gordy, James T, Luo, Kun, Francica, Brian, Drake, Charles, Markham, Richard B
Published in Journal of immunotherapy (1997) (01.05.2018)
Published in Journal of immunotherapy (1997) (01.05.2018)
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A phase 1 study of TPST-1495 as a single agent and in combination with pembrolizumab in subjects with solid tumors
Davar, Diwakar, Powderly, John D., Ulahannan, Susanna Varkey, Johnson, Melissa Lynne, Sharma, Manish, Krauss, John C., Stagg, Robert, Francica, Brian, Moon, Anne, Jenkins, Yonchu, Prasit, Peppi, Dubensky, Thomas Walter, Whiting, Sam H., Papadopoulos, Kyriakos P.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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CLL-1-Targeted Allogeneic CAR-T Cells Exhibit High on-Target Specificity and Potent Cytotoxicity in Preclinical Models of Acute Myeloid Leukemia
Francica, Brian, Garner, Elizabeth, Namburi, Sai, Colgan, Cian, Fowler, Tristan, Mutha, Devin, Aviles, Art, Stanaway, Morena, Guo, Raymond, An, Zili, Kelly, Erin, Degagne, Emilie, Kwong, George, Edwards, Leslie, Jakes, Emma, Shaw, McKay, Schilling, Benjamin, Huynh, Jeremy, Luu, Ricky, Sidorov, Max, Mousali, Rhonda, Otsmaa, Mikk, Lauer, Peter, Skoble, Justin, Kanner, Steven
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance
Martin, A M, Nirschl, T R, Nirschl, C J, Francica, B J, Kochel, C M, van Bokhoven, A, Meeker, A K, Lucia, M S, Anders, R A, DeMarzo, A M, Drake, C G
Published in Prostate cancer and prostatic diseases (01.12.2015)
Published in Prostate cancer and prostatic diseases (01.12.2015)
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Abstract 1203: Preclinical development of ADU-1805, a highly selective pan-allele anti-SIRPα antibody that blocks the SIRPα-CD47 innate immune checkpoint
Voets, Erik, Kreijtz, Joost, Vink, Paul, Hulsik, David Lutje, Parade, Mark, Spijkers, Sanne, Reinieren-Beeren, Inge, Rens, Joost, Janssen, Wout, Zandvoort, Peter van, Francica, Brian, Leong, Meredith, Elsas, Andrea van, Eenennaam, Hans van
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 2075: Systemic small molecule TREX1 inhibitors to selectively activate STING in the TME of metastatic disease
Francica, Brian, Burdette, Dara, Clark, Ryan, Cope, Jamie, Freund, David, Holtz, Anja, Prasit, Peppi, Whiting, Chan, Dubensky, Thomas W.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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