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Fineran, Paul, Lloyd-Evans, Emyr, Lack, Nathan A, Platt, Nick, Davis, Lianne C, Morgan, Anthony J, Höglinger, Doris, Tatituri, Raju Venkata V, Clark, Simon, Williams, Ian M, Tynan, Patricia, Al Eisa, Nada, Nazarova, Evgeniya, Williams, Ann, Galione, Antony, Ory, Daniel S, Besra, Gurdyal S, Russell, David G, Brenner, Michael B, Sim, Edith, Platt, Frances M
Published in Wellcome open research (2017)
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Hallett, Penelope J., Huebecker, Mylene, Brekk, Oeystein R., Moloney, Elizabeth B., Rocha, Emily M., Priestman, David A., Platt, Frances M., Isacson, Ole
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Published in Neurobiology of aging (01.07.2018)
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Reversible Infertility in Male Mice after Oral Administration of Alkylated Imino Sugars: A Nonhormonal Approach to Male Contraception
van der Spoel, Aarnoud C., Jeyakumar, Mylvaganam, Butters, Terry D., Charlton, Harry M., Moore, Harry D., Dwek, Raymond A., Platt, Frances M.
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.2002)
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Glucosylceramide modulates membrane traffic along the endocytic pathway
Sillence, Dan J, Puri, Vishwajeet, Marks, David L, Butters, Terry D, Dwek, Raymond A, Pagano, Richard E, Platt, Frances M
Published in Journal of lipid research (01.11.2002)
Published in Journal of lipid research (01.11.2002)
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Cholera intoxication of human enteroids reveals interplay between decoy and functional glycoconjugate ligands
Singla, Akshi, Boucher, Andrew, Wallom, Kerri-Lee, Lebens, Michael, Kohler, Jennifer J, Platt, Frances M, Yrlid, Ulf
Published in Glycobiology (Oxford) (30.10.2023)
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Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
Boland, Barry, Kumar, Asok, Lee, Sooyeon, Platt, Frances M, Wegiel, Jerzy, Yu, W. Haung, Nixon, Ralph A
Published in The Journal of neuroscience (02.07.2008)
Published in The Journal of neuroscience (02.07.2008)
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Expression of Ca2+-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells
Ruas, Margarida, Davis, Lianne C, Chen, Cheng-Chang, Morgan, Anthony J, Chuang, Kai-Ting, Walseth, Timothy F, Grimm, Christian, Garnham, Clive, Powell, Trevor, Platt, Nick, Platt, Frances M, Biel, Martin, Wahl-Schott, Christian, Parrington, John, Galione, Antony
Published in The EMBO journal (02.07.2015)
Published in The EMBO journal (02.07.2015)
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Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
Lloyd-Evans, Emyr, Platt, Frances M, Morgan, Anthony J, He, Xingxuan, Smith, David A, Elliot-Smith, Elena, Sillence, Daniel J, Churchill, Grant C, Schuchman, Edward H, Galione, Antony
Published in Nature medicine (01.11.2008)
Published in Nature medicine (01.11.2008)
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Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease
Schwerd, Tobias, Pandey, Sumeet, Yang, Huei-Ting, Bagola, Katrin, Jameson, Elisabeth, Jung, Jonathan, Lachmann, Robin H, Shah, Neil, Patel, Smita Y, Booth, Claire, Runz, Heiko, Düker, Gesche, Bettels, Ruth, Rohrbach, Marianne, Kugathasan, Subra, Chapel, Helen, Keshav, Satish, Elkadri, Abdul, Platt, Nick, Muise, Alexio M, Koletzko, Sibylle, Xavier, Ramnik J, Marquardt, Thorsten, Powrie, Fiona, Wraith, James E, Gyrd-Hansen, Mads, Platt, Frances M, Uhlig, Holm H
Published in Gut (01.06.2017)
Published in Gut (01.06.2017)
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N‐butyldeoxygalactonojirimycin reduces neonatal brain ganglioside content in a mouse model of GM1 gangliosidosis
Kasperzyk, Julie L., El‐Abbadi, Mohga M., Hauser, Eric C., D'Azzo, Alessandra, Platt, Frances M., Seyfried, Thomas N.
Published in Journal of neurochemistry (01.05.2004)
Published in Journal of neurochemistry (01.05.2004)
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Improved outcome of N-butyldeoxygalactonojirimycin-mediated substrate reduction therapy in a mouse model of Sandhoff disease
Andersson, Ulrika, Smith, David, Jeyakumar, Mylvaganam, Butters, Terry D, Borja, Mario Cortina, Dwek, Raymond A, Platt, Frances M
Published in Neurobiology of disease (01.08.2004)
Published in Neurobiology of disease (01.08.2004)
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Drug‐induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann–Pick type C cells and mice
Moreau, Dimitri, Vacca, Fabrizio, Vossio, Stefania, Scott, Cameron, Colaco, Alexandria, Paz Montoya, Jonathan, Ferguson, Charles, Damme, Markus, Moniatte, Marc, Parton, Robert G, Platt, Frances M, Gruenberg, Jean
Published in EMBO reports (01.07.2019)
Published in EMBO reports (01.07.2019)
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AAV9 intracerebroventricular gene therapy improves lifespan, locomotor function and pathology in a mouse model of Niemann-Pick type C1 disease
Hughes, Michael P, Smith, Dave A, Morris, Lauren, Fletcher, Claire, Colaco, Alexandria, Huebecker, Mylene, Tordo, Julie, Palomar, Nuria, Massaro, Giulia, Henckaerts, Els, Waddington, Simon N, Platt, Frances M, Rahim, Ahad A
Published in Human molecular genetics (01.09.2018)
Published in Human molecular genetics (01.09.2018)
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Systemic AAV9 gene therapy using the synapsin I promoter rescues a mouse model of neuronopathic Gaucher disease but with limited cross-correction potential to astrocytes
Massaro, Giulia, Hughes, Michael P, Whaler, Sammie M, Wallom, Kerri-Lee, Priestman, David A, Platt, Frances M, Waddington, Simon N, Rahim, Ahad A
Published in Human molecular genetics (29.07.2020)
Published in Human molecular genetics (29.07.2020)
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Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice
Moreau, Dimitri, Vacca, Fabrizio, Vossio, Stefania, Scott, Cameron, Colaco, Alexandria, Paz Montoya, Jonathan, Ferguson, Charles, Damme, Markus, Moniatte, Marc, Parton, Robert G, Platt, Frances M, Gruenberg, Jean
Published in EMBO reports (01.07.2019)
Published in EMBO reports (01.07.2019)
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Alkylated Imino Sugars, Reversible Male Infertility-Inducing Agents, Do Not Affect the Genetic Integrity of Male Mouse Germ Cells During Short-Term Treatment Despite Induction of Sperm Deformities
SUGANUMA, Ryota, WALDEN, Charlotte M, BUTTERS, Terry D, PLATT, Frances M, DWEK, Raymond A, YANAGIMACHI, Ryuzo, VAN DER SPOEL, Aarnoud C
Published in Biology of reproduction (01.04.2005)
Published in Biology of reproduction (01.04.2005)
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