E-cadherin-integrin crosstalk in cancer invasion and metastasis
Canel, Marta, Serrels, Alan, Frame, Margaret C, Brunton, Valerie G
Published in Journal of cell science (15.01.2013)
Published in Journal of cell science (15.01.2013)
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Journal Article
Targeting FAK in anticancer combination therapies
Dawson, John C., Serrels, Alan, Stupack, Dwayne G., Schlaepfer, David D., Frame, Margaret C.
Published in Nature reviews. Cancer (01.05.2021)
Published in Nature reviews. Cancer (01.05.2021)
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Journal Article
Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity
Serrels, Alan, Lund, Tom, Serrels, Bryan, Byron, Adam, McPherson, Rhoanne C., von Kriegsheim, Alexander, Gómez-Cuadrado, Laura, Canel, Marta, Muir, Morwenna, Ring, Jennifer E., Maniati, Eleni, Sims, Andrew H., Pachter, Jonathan A., Brunton, Valerie G., Gilbert, Nick, Anderton, Stephen M., Nibbs, Robert J.B., Frame, Margaret C.
Published in Cell (24.09.2015)
Published in Cell (24.09.2015)
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Journal Article
The FERM domain: organizing the structure and function of FAK
Frame, Margaret C, Eck, Michael J, Patel, Hitesh, Serrels, Bryan, Lietha, Daniel
Published in Nature reviews. Molecular cell biology (01.11.2010)
Published in Nature reviews. Molecular cell biology (01.11.2010)
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Journal Article
Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer
Morton, Jennifer P, Timpson, Paul, Karim, Saadia A, Ridgway, Rachel A, Athineos, Dimitris, Doyle, Brendan, Jamieson, Nigel B, Oien, Karin A, Lowy, Andrew M, Brunton, Valerie G, Frame, Margaret C, Evans, T.R. Jeffry, Sansom, Owen J
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
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Journal Article
The role of focal-adhesion kinase in cancer - a new therapeutic opportunity
Frame, Margaret C, McLean, Gordon W, Carragher, Neil O, Avizienyte, Egle, Evans, Jeff, Brunton, Valerie G
Published in Nature reviews. Cancer (01.07.2005)
Published in Nature reviews. Cancer (01.07.2005)
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Journal Article
ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival
Kanellos, Georgios, Zhou, Jing, Patel, Hitesh, Ridgway, Rachel A., Huels, David, Gurniak, Christine B., Sandilands, Emma, Carragher, Neil O., Sansom, Owen J., Witke, Walter, Brunton, Valerie G., Frame, Margaret C.
Published in Cell reports (Cambridge) (01.12.2015)
Published in Cell reports (Cambridge) (01.12.2015)
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Journal Article
Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression
Li Mow Chee, Frederic, Beernaert, Bruno, Griffith, Billie G. C., Loftus, Alexander E. P., Kumar, Yatendra, Wills, Jimi C., Lee, Martin, Valli, Jessica, Wheeler, Ann P., Armstrong, J. Douglas, Parsons, Maddy, Leigh, Irene M., Proby, Charlotte M., von Kriegsheim, Alex, Bickmore, Wendy A., Frame, Margaret C., Byron, Adam
Published in Nature communications (23.03.2023)
Published in Nature communications (23.03.2023)
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Journal Article
p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy
Sandilands, Emma, Schoenherr, Christina, Frame, Margaret C.
Published in Cellular signalling (01.09.2015)
Published in Cellular signalling (01.09.2015)
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Journal Article
Loss of Scar/WAVE Complex Promotes N-WASP- and FAK-Dependent Invasion
Tang, Haoran, Li, Ang, Bi, Jing, Veltman, Douwe M., Zech, Tobias, Spence, Heather J., Yu, Xinzi, Timpson, Paul, Insall, Robert H., Frame, Margaret C., Machesky, Laura M.
Published in Current biology (21.01.2013)
Published in Current biology (21.01.2013)
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Journal Article
Characterisation of a nucleo-adhesome
Byron, Adam, Griffith, Billie G. C., Herrero, Ana, Loftus, Alexander E. P., Koeleman, Emma S., Kogerman, Linda, Dawson, John C., McGivern, Niamh, Culley, Jayne, Grimes, Graeme R., Serrels, Bryan, von Kriegsheim, Alex, Brunton, Valerie G., Frame, Margaret C.
Published in Nature communications (01.06.2022)
Published in Nature communications (01.06.2022)
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Journal Article
FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs
Griffith, Billie G. C., Upstill-Goddard, Rosanna, Brunton, Holly, Grimes, Graeme R., Biankin, Andrew V., Serrels, Bryan, Byron, Adam, Frame, Margaret C.
Published in Scientific reports (08.01.2021)
Published in Scientific reports (08.01.2021)
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Journal Article
Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic Cancer
NOBIS, Max, MCGHEE, Ewan J, BRUNTON, Valerie G, FRAME, Margaret C, CARRAGHER, Neil O, YINGXIAO WANG, SANSOM, Owen J, TIMPSON, Paul, ANDERSON, Kurt I, MORTON, Jennifer P, SCHWARZ, Juliane P, KARIM, Saadia A, QUINN, Jean, EDWARD, Mike, CAMPBELL, Andrew D, MCGARRY, Lynn C, EVANS, T. R. Jeffry
Published in Cancer research (Chicago, Ill.) (01.08.2013)
Published in Cancer research (Chicago, Ill.) (01.08.2013)
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Journal Article
Kindlin-1 regulates IL-6 secretion and modulates the immune environment in breast cancer models
Webb, Emily R, Dodd, Georgia L, Noskova, Michaela, Bullock, Esme, Muir, Morwenna, Frame, Margaret C, Serrels, Alan, Brunton, Valerie G
Published in eLife (08.03.2023)
Published in eLife (08.03.2023)
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Journal Article
Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression
Lahlou, Hicham, Sanguin-Gendreau, Virginie, Zuo, Dongmei, Cardiff, Robert.D, McLean, Gordon W, Frame, Margaret C, Muller, William J
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (18.12.2007)
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