Diverse Effects on M1 Signaling and Adverse Effect Liability within a Series of M1 Ago-PAMs
Rook, Jerri M, Abe, Masahito, Cho, Hyekyung P, Nance, Kellie D, Luscombe, Vincent B, Adams, Jeffrey J, Dickerson, Jonathan W, Remke, Daniel H, Garcia-Barrantes, Pedro M, Engers, Darren W, Engers, Julie L, Chang, Sichen, Foster, Jarrett J, Blobaum, Anna L, Niswender, Colleen M, Jones, Carrie K, Conn, P. Jeffrey, Lindsley, Craig W
Published in ACS chemical neuroscience (19.04.2017)
Published in ACS chemical neuroscience (19.04.2017)
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Journal Article
Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition
Wood, Michael R., Noetzel, Meredith J., Tarr, James C., Rodriguez, Alice L., Lamsal, Atin, Chang, Sichen, Foster, Jarrett J., Smith, Emery, Chase, Peter, Hodder, Peter S., Engers, Darren W., Niswender, Colleen M., Brandon, Nicholas J., Wood, Michael W., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Get full text
Journal Article
Diverse Effects on M 1 Signaling and Adverse Effect Liability within a Series of M 1 Ago-PAMs
Rook, Jerri M, Abe, Masahito, Cho, Hyekyung P, Nance, Kellie D, Luscombe, Vincent B, Adams, Jeffrey J, Dickerson, Jonathan W, Remke, Daniel H, Garcia-Barrantes, Pedro M, Engers, Darren W, Engers, Julie L, Chang, Sichen, Foster, Jarrett J, Blobaum, Anna L, Niswender, Colleen M, Jones, Carrie K, Conn, P Jeffrey, Lindsley, Craig W
Published in ACS chemical neuroscience (19.04.2017)
Published in ACS chemical neuroscience (19.04.2017)
Get full text
Journal Article
Discovery and SAR of a novel series of potent, CNS penetrant M-4 PAMs based on a non-enolizable ketone core: Challenges in disposition
Wood, Michael R., Noetzel, Meredith J., Tarr, James C., Rodriguez, Alice L., Lamsal, Atin, Chang, Sichen, Foster, Jarrett J., Smith, Emery, Chase, Peter, Hodder, Peter S., Engers, Darren W., Niswender, Colleen M., Brandon, Nicholas J., Wood, Michael W., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Get full text
Journal Article