Assessment of romosozumab efficacy in the treatment of postmenopausal osteoporosis: Results from a mechanistic PK-PD mechanostat model of bone remodeling
Martin, Madge, Sansalone, Vittorio, Cooper, David M.L., Forwood, Mark R., Pivonka, Peter
Published in Bone (New York, N.Y.) (01.04.2020)
Published in Bone (New York, N.Y.) (01.04.2020)
Get full text
Journal Article
Effects of PTH glandular and external dosing patterns on bone cell activity using a two-state receptor model-Implications for bone disease progression and treatment
Martonová, Denisa, Lavaill, Maxence, Forwood, Mark R, Robling, Alexander, Cooper, David M L, Leyendecker, Sigrid, Pivonka, Peter
Published in PloS one (30.03.2023)
Published in PloS one (30.03.2023)
Get full text
Journal Article
Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection
Chen, Weiqiang, Foo, Suan-Sin, Taylor, Adam, Lulla, Aleksei, Merits, Andres, Hueston, Linda, Forwood, Mark R, Walsh, Nicole C, Sims, Natalie A, Herrero, Lara J, Mahalingam, Suresh
Published in Journal of virology (01.01.2015)
Published in Journal of virology (01.01.2015)
Get full text
Journal Article
Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone
Vrahnas, Christina, Blank, Martha, Dite, Toby A., Tatarczuch, Liliana, Ansari, Niloufar, Crimeen-Irwin, Blessing, Nguyen, Huynh, Forwood, Mark R., Hu, Yifang, Ikegame, Mika, Bambery, Keith R., Petibois, Cyril, Mackie, Eleanor J., Tobin, Mark J., Smyth, Gordon K., Oakhill, Jonathan S., Martin, T. John, Sims, Natalie A.
Published in Nature communications (31.07.2019)
Published in Nature communications (31.07.2019)
Get full text
Journal Article
Autocrine and Paracrine Regulation of the Murine Skeleton by Osteocyte‐Derived Parathyroid Hormone‐Related Protein
Ansari, Niloufar, Ho, Patricia WM, Crimeen‐Irwin, Blessing, Poulton, Ingrid J, Brunt, Athena R, Forwood, Mark R, Divieti Pajevic, Paola, Gooi, Jonathan H, Martin, T John, Sims, Natalie A
Published in Journal of bone and mineral research (01.01.2018)
Published in Journal of bone and mineral research (01.01.2018)
Get full text
Journal Article
Pentosan Polysulfate: a Novel Glycosaminoglycan-Like Molecule for Effective Treatment of Alphavirus-Induced Cartilage Destruction and Inflammatory Disease
Herrero, Lara J, Foo, Suan-Sin, Sheng, Kuo-Ching, Chen, Weiqiang, Forwood, Mark R, Bucala, Richard, Mahalingam, Suresh
Published in Journal of virology (01.08.2015)
Published in Journal of virology (01.08.2015)
Get full text
Journal Article
The Primary Function of gp130 Signaling in Osteoblasts Is To Maintain Bone Formation and Strength, Rather Than Promote Osteoclast Formation
Johnson, Rachelle W, Brennan, Holly J, Vrahnas, Christina, Poulton, Ingrid J, McGregor, Narelle E, Standal, Therese, Walker, Emma C, Koh, Thuan‐Tzen, Nguyen, Huynh, Walsh, Nicole C, Forwood, Mark R, Martin, T John, Sims, Natalie A
Published in Journal of bone and mineral research (01.06.2014)
Published in Journal of bone and mineral research (01.06.2014)
Get full text
Journal Article
Heterogeneity in microstructural deterioration following spinal cord injury
Ghasem-Zadeh, Ali, Galea, Mary P., Nunn, Andrew, Panisset, Maya, Wang, Xiao-Fang, Iuliano, Sandra, Boyd, Steven K., Forwood, Mark R., Seeman, Ego
Published in Bone (New York, N.Y.) (01.01.2021)
Published in Bone (New York, N.Y.) (01.01.2021)
Get full text
Journal Article
Inhibition of Interleukin‐1β Signaling by Anakinra Demonstrates a Critical Role of Bone Loss in Experimental Arthritogenic Alphavirus Infections
Wolf, Stefan, Taylor, Adam, Zaid, Ali, Freitas, Joseph, Herrero, Lara J., Rao, Shambhavi, Suhrbier, Andreas, Forwood, Mark R., Bucala, Richard, Mahalingam, Suresh
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2019)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2019)
Get full text
Journal Article
Mechanobiological osteocyte feedback drives mechanostat regulation of bone in a multiscale computational model
Martin, Madge, Sansalone, Vittorio, Cooper, David M. L., Forwood, Mark R., Pivonka, Peter
Published in Biomechanics and modeling in mechanobiology (01.10.2019)
Published in Biomechanics and modeling in mechanobiology (01.10.2019)
Get full text
Journal Article
Study of the combined effects of PTH treatment and mechanical loading in postmenopausal osteoporosis using a new mechanistic PK-PD model
Lavaill, Maxence, Trichilo, Silvia, Scheiner, Stefan, Forwood, Mark R., Cooper, David M. L., Pivonka, Peter
Published in Biomechanics and modeling in mechanobiology (01.10.2020)
Published in Biomechanics and modeling in mechanobiology (01.10.2020)
Get full text
Journal Article
EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis
Tonna, Stephen, Takyar, Farzin M, Vrahnas, Christina, Crimeen-Irwin, Blessing, Ho, Patricia W M, Poulton, Ingrid J, Brennan, Holly J, McGregor, Narelle E, Allan, Elizabeth H, Nguyen, Huynh, Forwood, Mark R, Tatarczuch, Liliana, Mackie, Eleanor J, Martin, T John, Sims, Natalie A
Published in The FASEB journal (01.10.2014)
Published in The FASEB journal (01.10.2014)
Get more information
Journal Article
The effect of low-intensity whole-body vibration with or without high-intensity resistance and impact training on risk factors for proximal femur fragility fracture in postmenopausal women with low bone mass: study protocol for the VIBMOR randomized controlled trial
Beck, Belinda, Rubin, Clinton, Harding, Amy, Paul, Sanjoy, Forwood, Mark
Published in Current controlled trials in cardiovascular medicine (06.01.2022)
Published in Current controlled trials in cardiovascular medicine (06.01.2022)
Get full text
Journal Article
Dmp1Cre‐directed knockdown of parathyroid hormone–related protein (PTHrP) in murine decidua is associated with a life‐long increase in bone mass, width, and strength in male progeny
Ansari, Niloufar, Isojima, Tsuyoshi, Crimeen‐Irwin, Blessing, Poulton, Ingrid J., McGregor, Narelle E., Ho, Patricia W. M., Forwood, Mark R., Kovacs, Christopher S., Dimitriadis, Evdokia, Gooi, Jonathan H., Martin, T. John, Sims, Natalie A.
Published in Journal of bone and mineral research (01.10.2021)
Published in Journal of bone and mineral research (01.10.2021)
Get full text
Journal Article
Differential Expression of Chemokines, Chemokine Receptors and Proteinases by Foreign Body Giant Cells (FBGCs) and Osteoclasts
Khan, Usman A., Hashimi, Saeed M., Khan, Shershah, Quan, Jingjing, Bakr, Mahmoud M., Forwood, Mark R., Morrison, Nigel M.
Published in Journal of cellular biochemistry (01.07.2014)
Published in Journal of cellular biochemistry (01.07.2014)
Get full text
Journal Article
Foreign body giant cells and osteoclasts are TRAP positive, have podosome-belts and both require OC-STAMP for cell fusion
Khan, Usman A., Hashimi, Saeed M., Bakr, Mahmoud M., Forwood, Mark R., Morrison, Nigel A.
Published in Journal of cellular biochemistry (01.08.2013)
Published in Journal of cellular biochemistry (01.08.2013)
Get full text
Journal Article