Synthesis of site-specific antibody-drug conjugates using unnatural amino acids
Axup, Jun Y, Bajjuri, Krishna M, Ritland, Melissa, Hutchins, Benjamin M, Kim, Chan Hyuk, Kazane, Stephanie A, Halder, Rajkumar, Forsyth, Jane S, Santidrian, Antonio F, Stafin, Karin, Lu, Yingchun, Tran, Hon, Seller, Aaron J, Biroc, Sandra L, Szydlik, Aga, Pinkstaff, Jason K, Tian, Feng, Sinha, Subhash C, Felding-Habermann, Brunhilde, Smider, Vaughn V, Schultz, Peter G
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
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A CXCR4-Targeted Site-Specific Antibody-Drug Conjugate
Kularatne, Sumith A., Deshmukh, Vishal, Ma, Jennifer, Tardif, Virginie, Lim, Reyna K. V., Pugh, Holly M., Sun, Ying, Manibusan, Anthony, Sellers, Aaron J., Barnett, Richard S., Srinagesh, Shailaja, Forsyth, Jane S., Hassenpflug, Wolf, Tian, Feng, Javahishvili, Tsotne, Felding-Habermann, Brunhilde, Lawson, Brian R., Kazane, Stephanie A., Schultz, Peter G.
Published in Angewandte Chemie (International ed.) (27.10.2014)
Published in Angewandte Chemie (International ed.) (27.10.2014)
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SMI-Ribosome inactivating protein conjugates selectively inhibit tumor cell growth
Roy, Saumya, Axup, Jun Y., Forsyth, Jane S., Goswami, Rajib K., Hutchins, Benjamin M., Bajuri, Krishna M., Kazane, Stephanie A., Smider, Vaughn V., Felding, Brunhilde H., Sinha, Subhash C.
Published in Chemical communications (Cambridge, England) (2017)
Published in Chemical communications (Cambridge, England) (2017)
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Nicotinamide phosphoribosyltransferase can affect metastatic activity and cell adhesive functions by regulating integrins in breast cancer
Santidrian, Antonio F., LeBoeuf, Sarah E., Wold, Erik D., Ritland, Melissa, Forsyth, Jane S., Felding, Brunhilde H.
Published in DNA repair (01.11.2014)
Published in DNA repair (01.11.2014)
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Site-Specific Coupling and Sterically Controlled Formation of Multimeric Antibody Fab Fragments with Unnatural Amino Acids
Hutchins, Benjamin M., Kazane, Stephanie A., Staflin, Karin, Forsyth, Jane S., Felding-Habermann, Brunhilde, Schultz, Peter G., Smider, Vaughn V.
Published in Journal of molecular biology (04.03.2011)
Published in Journal of molecular biology (04.03.2011)
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Chemically Programmed Antibodies Targeting Multiple Alpha(v) Integrins and Their Effects on Tumor-Related Functions in Vitro
Goswami, Rajib K, Bajjuri, Krishna M, Forsyth, Jane S, Das, Sanjib, Hassenpflug, Wolf, Huang, Zheng-Zheng, Lerner, Richard A, Felding-Habermann, Brunhilde, Sinha, Subhash C
Published in Bioconjugate chemistry (17.08.2011)
Published in Bioconjugate chemistry (17.08.2011)
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Selective Formation of Covalent Protein Heterodimers with an Unnatural Amino Acid
Hutchins, Benjamin M., Kazane, Stephanie A., Staflin, Karin, Forsyth, Jane S., Felding-Habermann, Brunhilde, Smider, Vaughn V., Schultz, Peter G.
Published in Chemistry & biology (25.03.2011)
Published in Chemistry & biology (25.03.2011)
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Targeting activated integrin αvβ3 with patient-derived antibodies impacts late-stage multiorgan metastasis
Staflin, Karin, Krueger, Joseph S, Hachmann, Janna, Forsyth, Jane S, Lorger, Mihaela, Steiniger, Sebastian C. J, Mee, Jenny, Pop, Cristina, Salvesen, Guy S, Janda, Kim D, Felding-Habermann, Brunhilde
Published in Clinical & experimental metastasis (01.04.2010)
Published in Clinical & experimental metastasis (01.04.2010)
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Ribosome-Inactivating Protein–Small Molecule Conjugates can Selectively Inhibit Target-Specific Tumor Cell Growth
Roy, Saumya, Axup, Jun Y., Forsyth, Jane S., Goswami, Rajib K., Hutchins, Benjamin M., Bajuri, Krishna M., Kazane, Stephanie A., Smider, Vaughn V., Felding, Brunhilde H., Sinha, Subhash C.
Published in Chemical communications (Cambridge, England) (11.04.2017)
Published in Chemical communications (Cambridge, England) (11.04.2017)
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Journal Article
SMI-Ribosome inactivating protein conjugates selectively inhibit tumor cell growthElectronic supplementary information (ESI) available: Synthesis of compounds 3 and 4, and production and evaluation of the SMI-Sap, SMI(AF)-Sap, and cpAb 38C2-1. See DOI: 10.1039/c7cc00745k
Roy, Saumya, Axup, Jun Y, Forsyth, Jane S, Goswami, Rajib K, Hutchins, Benjamin M, Bajuri, Krishna M, Kazane, Stephanie A, Smider, Vaughn V, Felding, Brunhilde H, Sinha, Subhash C
Year of Publication 11.04.2017
Year of Publication 11.04.2017
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Journal Article
A CXCR4-Targeted Site-Specific Antibody-Drug Conjugate
Kularatne, Sumith A., Deshmukh, Vishal, Ma, Jennifer, Tardif, Virginie, Lim, Reyna K. V., Pugh, Holly M., Sun, Ying, Manibusan, Anthony, Sellers, Aaron J., Barnett, Richard S., Srinagesh, Shailaja, Forsyth, Jane S., Hassenpflug, Wolf, Tian, Feng, Javahishvili, Tsotne, Felding-Habermann, Brunhilde, Lawson, Brian R., Kazane, Stephanie A., Schultz, Peter G.
Published in Angewandte Chemie (27.10.2014)
Published in Angewandte Chemie (27.10.2014)
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Journal Article
Targeting activated integrin alphavbeta3 with patient-derived antibodies impacts late-stage multiorgan metastasis
Staflin, Karin, Krueger, Joseph S, Hachmann, Janna, Forsyth, Jane S, Lorger, Mihaela, Steiniger, Sebastian C J, Mee, Jenny, Pop, Cristina, Salvesen, Guy S, Janda, Kim D, Felding-Habermann, Brunhilde
Published in Clinical & experimental metastasis (01.04.2010)
Published in Clinical & experimental metastasis (01.04.2010)
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