Neuroprotective and Disease-Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer's Disease
Parrado Fernandez, Cristina, Juric, Sanja, Backlund, Maria, Dahlström, Märta, Madjid, Nather, Lidell, Veronica, Rasti, Azita, Sandin, Johan, Nordvall, Gunnar, Forsell, Pontus
Published in International journal of molecular sciences (01.07.2023)
Published in International journal of molecular sciences (01.07.2023)
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Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
Naia, Luana, Pinho, Catarina M, Dentoni, Giacomo, Liu, Jianping, Leal, Nuno Santos, Ferreira, Duarte M S, Schreiner, Bernadette, Filadi, Riccardo, Fão, Lígia, Connolly, Niamh M C, Forsell, Pontus, Nordvall, Gunnar, Shimozawa, Makoto, Greotti, Elisa, Basso, Emy, Theurey, Pierre, Gioran, Anna, Joselin, Alvin, Arsenian-Henriksson, Marie, Nilsson, Per, Rego, A Cristina, Ruas, Jorge L, Park, David, Bano, Daniele, Pizzo, Paola, Prehn, Jochen H M, Ankarcrona, Maria
Published in BMC biology (24.03.2021)
Published in BMC biology (24.03.2021)
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Applicability of the Triad Concept for the Positional Specificity of Mammalian Lipoxygenases
Vogel, Robert, Jansen, Christian, Roffeis, Jana, Reddanna, Pallu, Forsell, Pontus, Claesson, Hans-Eric, Kuhn, Hartmut, Walther, Matthias
Published in The Journal of biological chemistry (19.02.2010)
Published in The Journal of biological chemistry (19.02.2010)
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Identification of Novel Positive Allosteric Modulators of Neurotrophin Receptors for the Treatment of Cognitive Dysfunction
Dahlström, Märta, Madjid, Nather, Nordvall, Gunnar, Halldin, Magnus M, Vazquez-Juarez, Erika, Lindskog, Maria, Sandin, Johan, Winblad, Bengt, Eriksdotter, Maria, Forsell, Pontus
Published in Cells (Basel, Switzerland) (23.07.2021)
Published in Cells (Basel, Switzerland) (23.07.2021)
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Metabolism of Anandamide into Eoxamides by 15-Lipoxygenase-1 and Glutathione Transferases
Forsell, Pontus K. A., Brunnström, Åsa, Johannesson, Malin, Claesson, Hans-Erik
Published in Lipids (01.08.2012)
Published in Lipids (01.08.2012)
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Journal Article
Basal Activation of p70S6K Results in Adipose-specific Insulin Resistance in Protein-tyrosine Phosphatase 1B–/– Mice
Ruffolo, Salvatore C., Forsell, Pontus K.A., Yuan, Xiling, Desmarais, Sylvie, Himms-Hagen, Jean, Cromlish, Wanda, Wong, Kenny K., Kennedy, Brian P.
Published in The Journal of biological chemistry (19.10.2007)
Published in The Journal of biological chemistry (19.10.2007)
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Development of a Fluorescent Intensity Assay Amenable for High-Throughput Screening for Determining 15-Lipoxygenase Activity
Dahlström, Märta, Forsström, Daniel, Johannesson, Malin, Huque-Andersson, Yasmin, Björk, Marie, Silfverplatz, Erik, Sanin, Andrei, Schaal, Wesley, Pelcman, Benjamin, Forsell, Pontus K.A.
Published in Journal of biomolecular screening (01.07.2010)
Published in Journal of biomolecular screening (01.07.2010)
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The expression of cytosolic phospholipase A2 and biosynthesis of leukotriene B4 in acute myeloid leukemia cells
Runarsson, Gudmundur, Feltenmark, Stina, Forsell, Pontus K. A., Sjöberg, Jan, Björkholm, Magnus, Claesson, Hans-Erik
Published in European journal of haematology (01.12.2007)
Published in European journal of haematology (01.12.2007)
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Polychlorinated biphenyls induce arachidonic acid release in human platelets in a tamoxifen sensitive manner via activation of group IVA cytosolic phospholipase A2-α
FORSELL, Pontus K. A, OLSSON, Anders O, ANDERSSON, Erik, NALLAN, Laxman, GELB, Michael H
Published in Biochemical pharmacology (19.12.2005)
Published in Biochemical pharmacology (19.12.2005)
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Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling – a potential therapeutic concept?
Madjid, Nather, Lidell, Veronica, Nordvall, Gunnar, Lindskog, Maria, Ögren, Sven-Ove, Forsell, Pontus, Sandin, Johan
Published in Psychopharmacology (01.08.2023)
Published in Psychopharmacology (01.08.2023)
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Journal Article
ACD856: A novel positive allosteric modulator of Trk‐signaling in clinical development for the treatment of Alzheimer’s disease
Nordvall, Gunnar, Madjid, Nather, Backlund, Maria, Halldin, Magnus, Rother, Matthias, Nilsson, Boel, Sandin, Johan, Forsell, Pontus
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Results From a Multiple Ascending Dose Study in Healthy Volunteers of ACD856, a Positive Modulator of Neurotrophin Trk‐Receptors
Önnestam, Kristin, Nilsson, Boel, Rother, Matthias, Rein‐Hedin, Erik, Bylund, Johan, Halldin, Magnus, Forsell, Pontus, Nordvall, Gunnar, Sandin, Johan, Segerdahl, Märta
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons
Dahlström, Märta, Nordvall, Gunnar, Sundström, Erik, Åkesson, Elisabet, Tegerstedt, Gunilla, Eriksdotter, Maria, Forsell, Pontus
Published in The European journal of neuroscience (01.11.2019)
Published in The European journal of neuroscience (01.11.2019)
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