Insulin-like growth factors: Ligands, binding proteins, and receptors
LeRoith, Derek, Holly, Jeff M.P., Forbes, Briony E.
Published in Molecular metabolism (Germany) (01.10.2021)
Published in Molecular metabolism (Germany) (01.10.2021)
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How ligand binds to the type 1 insulin-like growth factor receptor
Xu, Yibin, Kong, Geoffrey K-W, Menting, John G, Margetts, Mai B, Delaine, Carlie A, Jenkin, Lauren M, Kiselyov, Vladislav V, De Meyts, Pierre, Forbes, Briony E, Lawrence, Michael C
Published in Nature communications (26.02.2018)
Published in Nature communications (26.02.2018)
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Engineering of a Biologically Active Insulin Dimer
Liu, Mengjie, White, Barbara F, Praveen, Praveen, Li, Wenyi, Lin, Feng, Wu, Hongkang, Li, Rong, Delaine, Carlie, Forbes, Briony E, Wade, John D, Hossain, Mohammed Akhter
Published in Journal of medicinal chemistry (09.12.2021)
Published in Journal of medicinal chemistry (09.12.2021)
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How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor
Xu, Yibin, Kirk, Nicholas S., Venugopal, Hariprasad, Margetts, Mai B., Croll, Tristan I., Sandow, Jarrod J., Webb, Andrew I., Delaine, Carlie A., Forbes, Briony E., Lawrence, Michael C.
Published in Structure (London) (07.07.2020)
Published in Structure (London) (07.07.2020)
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Vortex Fluidic Mediated Oxidative Sulfitolysis of Oxytocin
Crawley, Emily M, Pye, Scott, Forbes, Briony E, Raston, Colin L
Published in Molecules (Basel, Switzerland) (07.02.2022)
Published in Molecules (Basel, Switzerland) (07.02.2022)
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Understanding IGF-II Action through Insights into Receptor Binding and Activation
Blyth, Andrew J, Kirk, Nicholas S, Forbes, Briony E
Published in Cells (Basel, Switzerland) (12.10.2020)
Published in Cells (Basel, Switzerland) (12.10.2020)
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Insulin-like growth factor binding proteins: a structural perspective
Forbes, Briony E, McCarthy, Peter, Norton, Raymond S
Published in Frontiers in endocrinology (Lausanne) (2012)
Published in Frontiers in endocrinology (Lausanne) (2012)
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Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor
Ahorukomeye, Peter, Disotuar, Maria M, Gajewiak, Joanna, Karanth, Santhosh, Watkins, Maren, Robinson, Samuel D, Flórez Salcedo, Paula, Smith, Nicholas A, Smith, Brian J, Schlegel, Amnon, Forbes, Briony E, Olivera, Baldomero, Hung-Chieh Chou, Danny, Safavi-Hemami, Helena
Published in eLife (12.02.2019)
Published in eLife (12.02.2019)
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2-Nitroveratryl as a Photocleavable Thiol-Protecting Group for Directed Disulfide Bond Formation in the Chemical Synthesis of Insulin
Karas, John A., Scanlon, Denis B., Forbes, Briony E., Vetter, Irina, Lewis, Richard J., Gardiner, James, Separovic, Frances, Wade, John D., Hossain, Mohammed A.
Published in Chemistry : a European journal (28.07.2014)
Published in Chemistry : a European journal (28.07.2014)
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Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone
Mitchell, Michela L, Hossain, Mohammed Akhter, Lin, Feng, Pinheiro-Junior, Ernesto L, Peigneur, Steve, Wai, Dorothy C C, Delaine, Carlie, Blyth, Andrew J, Forbes, Briony E, Tytgat, Jan, Wade, John D, Norton, Raymond S
Published in Biomolecules (Basel, Switzerland) (29.11.2021)
Published in Biomolecules (Basel, Switzerland) (29.11.2021)
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Structural Determinants for High-Affinity Binding of Insulin-Like Growth Factor II to Insulin Receptor (IR)-A, the Exon 11 Minus Isoform of the IR
Denley, Adam, Bonython, Eric R, Booker, Grant W, Cosgrove, Leah J, Forbes, Briony E, Ward, Colin W, Wallace, John C
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2004)
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2004)
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Alanine Scanning of a Putative Receptor Binding Surface of Insulin-like Growth Factor-I
Gauguin, Lisbeth, Delaine, Carlie, Alvino, Clair L., McNeil, Kerrie A., Wallace, John C., Forbes, Briony E., De Meyts, Pierre
Published in The Journal of biological chemistry (25.07.2008)
Published in The Journal of biological chemistry (25.07.2008)
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Structural Basis for the Lower Affinity of the Insulin-like Growth Factors for the Insulin Receptor
Gauguin, Lisbeth, Klaproth, Birgit, Sajid, Waseem, Andersen, Asser S., McNeil, Kerrie A., Forbes, Briony E., De Meyts, Pierre
Published in The Journal of biological chemistry (01.02.2008)
Published in The Journal of biological chemistry (01.02.2008)
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Precise mapping of an IGF-I-binding site on the IGF-1R
Keyhanfar, Mehrnaz, Booker, Grant W, Whittaker, Jonathan, Wallace, John C, Forbes, Briony E
Published in Biochemical journal (01.01.2007)
Published in Biochemical journal (01.01.2007)
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Journal Article
A Novel Approach to Identify Two Distinct Receptor Binding Surfaces of Insulin-like Growth Factor II
Alvino, Clair L., McNeil, Kerrie A., Ong, Shee Chee, Delaine, Carlie, Booker, Grant W., Wallace, John C., Whittaker, Jonathan, Forbes, Briony E.
Published in The Journal of biological chemistry (20.03.2009)
Published in The Journal of biological chemistry (20.03.2009)
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An Investigation of the Ligand Binding Properties and Negative Cooperativity of Soluble Insulin-like Growth Factor Receptors
Surinya, Katharina Helen, Forbes, Briony E., Occhiodoro, Filomena, Booker, Grant W., Francis, Geoffrey Leonard, Siddle, Kenneth, Wallace, John C., Cosgrove, Leah J.
Published in The Journal of biological chemistry (29.02.2008)
Published in The Journal of biological chemistry (29.02.2008)
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Journal Article
A Novel Binding Site for the Human Insulin-like Growth Factor-II (IGF-II)/Mannose 6-Phosphate Receptor on IGF-II
Delaine, Carlie, Alvino, Clair L., McNeil, Kerrie A., Mulhern, Terrance D., Gauguin, Lisbeth, De Meyts, Pierre, Jones, E. Yvonne, Brown, James, Wallace, John C., Forbes, Briony E.
Published in The Journal of biological chemistry (29.06.2007)
Published in The Journal of biological chemistry (29.06.2007)
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Journal Article
Cooperativity of the N- and C-Terminal Domains of Insulin-like Growth Factor (IGF) Binding Protein 2 in IGF Binding
Kuang, Zhihe, Yao, Shenggen, McNeil, Kerrie A, Thompson, Julian A, Bach, Leon A, Forbes, Briony E, Wallace, John C, Norton, Raymond S
Published in Biochemistry (Easton) (04.12.2007)
Published in Biochemistry (Easton) (04.12.2007)
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