Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology
Derada Troletti, Claudio, Fontijn, Ruud D., Gowing, Elizabeth, Charabati, Marc, van Het Hof, Bert, Didouh, Imad, van der Pol, Susanne M. A., Geerts, Dirk, Prat, Alexandre, van Horssen, Jack, Kooij, Gijs, de Vries, Helga E.
Published in Cell death & disease (18.01.2019)
Published in Cell death & disease (18.01.2019)
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Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis
Hansen, Cathrin E, Kamermans, Alwin, Mol, Kevin, Berve, Kristina, Rodriguez-Mogeda, Carla, Fung, Wing Ka, van Het Hof, Bert, Fontijn, Ruud D, van der Pol, Susanne M A, Michalick, Laura, Kuebler, Wolfgang M, Kenkhuis, Boyd, van Roon-Mom, Willeke, Liedtke, Wolfgang, Engelhardt, Britta, Kooij, Gijs, Witte, Maarten E, de Vries, Helga E
Published in Journal of neuroinflammation (23.03.2024)
Published in Journal of neuroinflammation (23.03.2024)
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Journal Article
Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation
Roig-Carles, David, Willms, Eduard, Fontijn, Ruud D., Martinez-Pacheco, Sarai, Mäger, Imre, de Vries, Helga E., Hirst, Mark, Sharrack, Basil, Male, David K., Hawkes, Cheryl A., Romero, Ignacio A.
Published in Pharmaceutics (21.09.2021)
Published in Pharmaceutics (21.09.2021)
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Journal Article
Galectin-2 induces a proinflammatory, anti-arteriogenic phenotype in monocytes and macrophages
Yıldırım, Cansu, Vogel, Daphne Y S, Hollander, Maurits R, Baggen, Josefien M, Fontijn, Ruud D, Nieuwenhuis, Sylvia, Haverkamp, Anouk, de Vries, Margreet R, Quax, Paul H A, Garcia-Vallejo, Juan J, van der Laan, Anja M, Dijkstra, Christine D, van der Pouw Kraan, Tineke C T M, van Royen, Niels, Horrevoets, Anton J G
Published in PloS one (17.04.2015)
Published in PloS one (17.04.2015)
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Expression of Nitric Oxide-Transporting Aquaporin-1 Is Controlled by KLF2 and Marks Non-Activated Endothelium In Vivo
Fontijn, Ruud D, Volger, Oscar L, van der Pouw-Kraan, Tineke C, Doddaballapur, Anuradha, Leyen, Thomas, Baggen, Josefien M, Boon, Reinier A, Horrevoets, Anton J G
Published in PloS one (30.12.2015)
Published in PloS one (30.12.2015)
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Journal Article
Vascular Endothelial Growth Factor remains unchanged in cerebrospinal fluid of patients with Alzheimer's disease and vascular dementia
Chakraborty, Ananya, Chatterjee, Madhurima, Twaalfhoven, Harry, Del Campo Milan, Marta, Teunissen, Charlotte E, Scheltens, Philip, Fontijn, Ruud D, van Der Flier, Wiesje M, de Vries, Helga E
Published in Alzheimer's research & therapy (23.06.2018)
Published in Alzheimer's research & therapy (23.06.2018)
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Journal Article
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium
Boon, Reinier A., Leyen, Thomas A., Fontijn, Ruud D., Fledderus, Joost O., Baggen, Josefien M.C., Volger, Oscar L., van Nieuw Amerongen, Geerten P., Horrevoets, Anton J.G.
Published in Blood (25.03.2010)
Published in Blood (25.03.2010)
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Journal Article
SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function
Fontijn, Ruud D, Volger, Oscar L, Fledderus, Joost O, Reijerkerk, Arie, de Vries, Helga E, Horrevoets, Anton J. G
Published in American journal of physiology. Heart and circulatory physiology (01.02.2008)
Published in American journal of physiology. Heart and circulatory physiology (01.02.2008)
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Journal Article
Profiling the unique protective properties of intracranial arterial endothelial cells
Hermkens, Dorien M A, Stam, Olga C G, de Wit, Nienke M, Fontijn, Ruud D, Jongejan, Aldo, Moerland, Perry D, Mackaaij, Claire, Waas, Ingeborg S E, Daemen, Mat J A P, de Vries, Helga E
Published in Acta neuropathologica communications (14.10.2019)
Published in Acta neuropathologica communications (14.10.2019)
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Journal Article
Endothelial CD81 is a marker of early human atherosclerotic plaques and facilitates monocyte adhesion
Rohlena, Jakub, Volger, Oscar L., van Buul, Jaap D., Hekking, Liesbeth H.P., van Gils, Janine M., Bonta, Peter I., Fontijn, Ruud D., Post, Jan Andries, Hordijk, Peter L., Horrevoets, Anton J.G.
Published in Cardiovascular research (01.01.2009)
Published in Cardiovascular research (01.01.2009)
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Journal Article
Angiopoietin like-4 as a novel vascular mediator in capillary cerebral amyloid angiopathy
Chakraborty, Ananya, Kamermans, Alwin, van het Hof, Bert, Castricum, Kitty, Aanhane, Ed, van Horssen, Jack, Thijssen, Victor L, Scheltens, Philip, Teunissen, Charlotte E, Fontijn, Ruud D, van der Flier, Wiesje M, de Vries, Helga E
Published in Brain (London, England : 1878) (01.12.2018)
Published in Brain (London, England : 1878) (01.12.2018)
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Journal Article
Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage
Szulcek, Robert, Happé, Chris M, Rol, Nina, Fontijn, Ruud D, Dickhoff, Chris, Hartemink, Koen J, Grünberg, Katrien, Tu, Ly, Timens, Wim, Nossent, George D, Paul, Marinus A, Leyen, Thomas A, Horrevoets, Anton J, de Man, Frances S, Guignabert, Christophe, Yu, Paul B, Vonk-Noordegraaf, Anton, van Nieuw Amerongen, Geerten P, Bogaard, Harm J
Published in American journal of respiratory and critical care medicine (15.06.2016)
Published in American journal of respiratory and critical care medicine (15.06.2016)
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Journal Article
Elevated monocyte-specific type I interferon signalling correlates positively with cardiac healing in myocardial infarct patients but interferon alpha application deteriorates myocardial healing in rats
ter Horst, Ellis N., Krijnen, Paul A. J., Hakimzadeh, Nazanin, Robbers, Lourens F. H. J., Hirsch, Alexander, Nijveldt, Robin, Lommerse, Ingrid, Fontijn, Ruud D., Meinster, Elisa, Delewi, Ronak, van Royen, Niels, Zijlstra, Felix, van Rossum, Albert C., van der Schoot, C. Ellen, van der Pouw Kraan, Tineke C. T. M., Horrevoets, Anton J., van der Laan, Anja M., Niessen, Hans W. M., Piek, Jan J.
Published in Basic research in cardiology (01.01.2019)
Published in Basic research in cardiology (01.01.2019)
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Journal Article
Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)
Dekker, Rob J., van Soest, Simone, Fontijn, Ruud D., Salamanca, Sonia, de Groot, Philip G., VanBavel, Ed, Pannekoek, Hans, Horrevoets, Anton J.G.
Published in Blood (01.09.2002)
Published in Blood (01.09.2002)
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Journal Article
Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner
Derada Troletti, Claudio, Lopes Pinheiro, Melissa A., Charabati, Marc, Gowing, Elizabeth, van het Hof, Bert, van der Pol, Susanne M.A., Geerts, Dirk, Prat, Alexandre, Fontijn, Ruud D., Unger, Wendy W., de Vries, Helga E.
Published in Brain, behavior, and immunity (01.03.2018)
Published in Brain, behavior, and immunity (01.03.2018)
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Journal Article
VEGF release by MMP-9 mediated heparan sulphate cleavage induces colorectal cancer angiogenesis
Hawinkels, Lukas J.A.C, Zuidwijk, Kim, Verspaget, Hein W, de Jonge-Muller, Eveline S.M, Duijn, Wim van, Ferreira, Valérie, Fontijn, Ruud D, David, Guido, Hommes, Daniel W, Lamers, Cornelis B.H.W, Sier, Cornelis F.M
Published in European journal of cancer (1990) (01.09.2008)
Published in European journal of cancer (1990) (01.09.2008)
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Journal Article
Krüppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells
BOON, Reinier A, URBICH, Carmen, FISCHER, Ariane, FONTIJN, Ruud D, SEEGER, Florian H, KOYANAGI, Masamichi, HORREVOETS, Anton J. G, DIMMELER, Stefanie
Published in European heart journal (01.02.2011)
Published in European heart journal (01.02.2011)
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