The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
Ashton, Thomas M, Fokas, Emmanouil, Kunz-Schughart, Leoni A, Folkes, Lisa K, Anbalagan, Selvakumar, Huether, Melanie, Kelly, Catherine J, Pirovano, Giacomo, Buffa, Francesca M, Hammond, Ester M, Stratford, Michael, Muschel, Ruth J, Higgins, Geoff S, McKenna, William Gillies
Published in Nature communications (25.07.2016)
Published in Nature communications (25.07.2016)
Get full text
Journal Article
Radiolysis Studies of Oxidation and Nitration of Tyrosine and Some Other Biological Targets by Peroxynitrite-Derived Radicals
Folkes, Lisa K, Bartesaghi, Silvina, Trujillo, Madia, Wardman, Peter, Radi, Rafael
Published in International journal of molecular sciences (04.02.2022)
Published in International journal of molecular sciences (04.02.2022)
Get full text
Journal Article
Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor
Skwarska, Anna, Calder, Ewen D.D., Sneddon, Deborah, Bolland, Hannah, Odyniec, Maria L., Mistry, Ishna N., Martin, Jennifer, Folkes, Lisa K., Conway, Stuart J., Hammond, Ester M.
Published in Cell chemical biology (16.09.2021)
Published in Cell chemical biology (16.09.2021)
Get full text
Journal Article
Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability
PIRES, Isabel M, BENCOKOVA, Zuzana, MILANI, Manuela, FOLKES, Lisa K, LI, Ji-Liang, STRATFORD, Mike R, HARRIS, Adrian L, HAMMOND, Ester M
Published in Cancer research (Chicago, Ill.) (01.02.2010)
Published in Cancer research (Chicago, Ill.) (01.02.2010)
Get full text
Journal Article
Kinetics of reduction of tyrosine phenoxyl radicals by glutathione
Folkes, Lisa K., Trujillo, Madia, Bartesaghi, Silvina, Radi, Rafael, Wardman, Peter
Published in Archives of biochemistry and biophysics (15.02.2011)
Published in Archives of biochemistry and biophysics (15.02.2011)
Get full text
Journal Article
Phase I Clinical Trial of Weekly Combretastatin A4 Phosphate: Clinical and Pharmacokinetic Results
RUSTIN, Gordon J. S, GALBRAITH, Susan M, ANDERSON, Helen, STRATFORD, Michael, FOLKES, Lisa K, SENA, Luiza, GUMBRELL, Lindsey, PRICE, Patricia M
Published in Journal of clinical oncology (01.08.2003)
Published in Journal of clinical oncology (01.08.2003)
Get full text
Journal Article
CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes
O’Connor, Liam J, Mistry, Ishna N, Collins, Sarah L, Folkes, Lisa K, Brown, Graham, Conway, Stuart J, Hammond, Ester M
Published in ACS central science (25.01.2017)
Published in ACS central science (25.01.2017)
Get full text
Journal Article
Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study
Ng, Quan-Sing, MRCP, Goh, Vicky, FRCR, Milner, Jessica, BSc, Stratford, Michael R, PhD, Folkes, Lisa K, BSc, Tozer, Gillian M, Prof, Saunders, Michele I, Prof, Hoskin, Peter J, Prof
Published in The lancet oncology (01.02.2007)
Published in The lancet oncology (01.02.2007)
Get full text
Journal Article
Identification of vitamin B1 metabolism as a tumor-specific radiosensitizing pathway using a high-throughput colony formation screen
Tiwana, Gaganpreet S, Prevo, Remko, Buffa, Francesca M, Yu, Sheng, Ebner, Daniel V, Howarth, Alison, Folkes, Lisa K, Budwal, Balam, Chu, Kwun-Ye, Durrant, Lisa, Muschel, Ruth J, McKenna, W Gillies, Higgins, Geoff S
Published in Oncotarget (20.03.2015)
Published in Oncotarget (20.03.2015)
Get full text
Journal Article
Radiosensitization by nitric oxide at low radiation doses
Wardman, Peter, Rothkamm, Kai, Folkes, Lisa K, Woodcock, Michael, Johnston, Peter J
Published in Radiation research (01.04.2007)
Published in Radiation research (01.04.2007)
Get more information
Journal Article
Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial
Lyon, Paul C, Gray, Michael D, Mannaris, Christophoros, Folkes, Lisa K, Stratford, Michael, Campo, Leticia, Chung, Daniel Y F, Scott, Shaun, Anderson, Mark, Goldin, Robert, Carlisle, Robert, Wu, Feng, Middleton, Mark R, Gleeson, Fergus V, Coussios, Constantin C
Published in The lancet oncology (01.08.2018)
Published in The lancet oncology (01.08.2018)
Get full text
Journal Article
Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial
Gray, Michael D, Lyon, Paul C, Mannaris, Christophoros, Folkes, Lisa K, Stratford, Michael, Campo, Leticia, Chung, Daniel Y F, Scott, Shaun, Anderson, Mark, Goldin, Robert, Carlisle, Robert, Wu, Feng, Middleton, Mark R, Gleeson, Fergus V, Coussios, Constantin C
Published in Radiology (01.04.2019)
Published in Radiology (01.04.2019)
Get full text
Journal Article
Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non-Small Cell Lung Cancer
Skwarski, Michael, McGowan, Daniel R, Belcher, Elizabeth, Di Chiara, Francesco, Stavroulias, Dionisios, McCole, Mark, Derham, Jennifer L, Chu, Kwun-Ye, Teoh, Eugene, Chauhan, Jagat, O'Reilly, Dawn, Harris, Benjamin H L, Macklin, Philip S, Bull, Joshua A, Green, Marcus, Rodriguez-Berriguete, Gonzalo, Prevo, Remko, Folkes, Lisa K, Campo, Leticia, Ferencz, Petra, Croal, Paula L, Flight, Helen, Qi, Cathy, Holmes, Jane, O'Connor, James P B, Gleeson, Fergus V, McKenna, W Gillies, Harris, Adrian L, Bulte, Daniel, Buffa, Francesca M, Macpherson, Ruth E, Higgins, Geoff S
Published in Clinical cancer research (01.05.2021)
Published in Clinical cancer research (01.05.2021)
Get full text
Journal Article
Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest
Carballal, Sebastián, Trujillo, Madia, Cuevasanta, Ernesto, Bartesaghi, Silvina, Möller, Matías N., Folkes, Lisa K., García-Bereguiaín, Miguel A., Gutiérrez-Merino, Carlos, Wardman, Peter, Denicola, Ana, Radi, Rafael, Alvarez, Beatriz
Published in Free radical biology & medicine (2011)
Published in Free radical biology & medicine (2011)
Get full text
Journal Article
Probing the limits of Q-tag bioconjugation of antibodies
Marculescu, Cristina, Lakshminarayanan, Abirami, Gault, Joseph, Knight, James C, Folkes, Lisa K, Spink, Thomas, Robinson, Carol V, Vallis, Katherine, Davis, Benjamin G, Cornelissen, Bart
Published in Chemical communications (Cambridge, England) (19.09.2019)
Published in Chemical communications (Cambridge, England) (19.09.2019)
Get full text
Journal Article
Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours
Roberts, Corran, Strauss, Victoria Y, Kopijasz, Sylwia, Gourley, Charlie, Hall, Marcia, Montes, Ana, Abraham, Jacinta, Clamp, Andrew, Kennedy, Richard, Banerjee, Susana, Folkes, Lisa K, Stratford, Michael, Nicum, Shibani
Published in British journal of cancer (01.02.2020)
Published in British journal of cancer (01.02.2020)
Get full text
Journal Article
Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction
Rieunier, Guillaume, Wu, Xiaoning, Harris, Letitia E, Mills, Jack V, Nandakumar, Ashwin, Colling, Laura, Seraia, Elena, Hatch, Stephanie B, Ebner, Daniel V, Folkes, Lisa K, Weyer-Czernilofsky, Ulrike, Bogenrieder, Thomas, Ryan, Anderson J, Macaulay, Valentine M
Published in Cancer research (Chicago, Ill.) (15.04.2021)
Published in Cancer research (Chicago, Ill.) (15.04.2021)
Get full text
Journal Article