Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase
Butler, Christopher R., Beck, Elizabeth M., Harris, Anthony, Huang, Zhen, McAllister, Laura A., am Ende, Christopher W., Fennell, Kimberly, Foley, Timothy L., Fonseca, Kari, Hawrylik, Steven J., Johnson, Douglas S., Knafels, John D., Mente, Scot, Noell, G. Stephen, Pandit, Jayvardhan, Phillips, Tracy B., Piro, Justin R., Rogers, Bruce N., Samad, Tarek A., Wang, Jane, Wan, Shuangyi, Brodney, Michael A.
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS)
Ratnayake, Anokha S., Flanagan, Mark E., Foley, Timothy L., Hultgren, Scott L., Bellenger, Justin, Montgomery, Justin I., Lall, Manjinder S., Liu, Bo, Ryder, Tim, Kölmel, Dominik K., Shavnya, Andre, Feng, Xidong, Lefker, Bruce, Byrnes, Laura J., Sahasrabudhe, Parag V., Farley, Kathleen A., Chen, Shi, Wan, Jinqiao
Published in Bioorganic & medicinal chemistry (01.07.2021)
Published in Bioorganic & medicinal chemistry (01.07.2021)
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Journal Article
Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries
Foley, Timothy L., Burchett, Woodrow, Chen, Qiuxia, Flanagan, Mark E., Kapinos, Brendon, Li, Xianyang, Montgomery, Justin I., Ratnayake, Anokha S., Zhu, Hongyao, Peakman, Marie-Claire
Published in SLAS discovery (01.02.2021)
Published in SLAS discovery (01.02.2021)
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Journal Article
Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors
Kosa, Nicolas M, Foley, Timothy L, Burkart, Michael D
Published in Journal of antibiotics (01.01.2014)
Published in Journal of antibiotics (01.01.2014)
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Journal Article
Preparation of FRET reporters to support chemical probe development
Foley, Timothy L., Yasgar, Adam, Garcia, Christopher J., Jadhav, Ajit, Simeonov, Anton, Burkart, Michael D.
Published in Organic & biomolecular chemistry (21.10.2010)
Published in Organic & biomolecular chemistry (21.10.2010)
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Journal Article
A method for estimating binding affinity from primary DEL selection data
Chen, Qiuxia, Hall, Justin, Foley, Timothy L., Wan, Jinqiao, Li, You, Israel, David I.
Published in Biochemical and biophysical research communications (03.12.2020)
Published in Biochemical and biophysical research communications (03.12.2020)
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Journal Article
A simple method for determining compound affinity and chemical yield from DNA-encoded library selections
Hall, Justin, Foley, Timothy L., Chen, Qiuxia, Israel, David I., Xu, Yanshan, Ford, Kristin K., Xie, Ping, Fan, Jing, Wan, Jinqiao
Published in Biochemical and biophysical research communications (18.06.2020)
Published in Biochemical and biophysical research communications (18.06.2020)
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Journal Article
A Solution Phase Platform to Characterize Chemical Reaction Compatibility with DNA-Encoded Chemical Library Synthesis
Ratnayake, Anokha S, Flanagan, Mark E, Foley, Timothy L, Smith, Justin D, Johnson, Jillian G, Bellenger, Justin, Montgomery, Justin I, Paegel, Brian M
Published in ACS combinatorial science (14.10.2019)
Published in ACS combinatorial science (14.10.2019)
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Journal Article
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation
McAllister, Laura A, Butler, Christopher R, Mente, Scot, O’Neil, Steven V, Fonseca, Kari R, Piro, Justin R, Cianfrogna, Julie A, Foley, Timothy L, Gilbert, Adam M, Harris, Anthony R, Helal, Christopher J, Johnson, Douglas S, Montgomery, Justin I, Nason, Deane M, Noell, Stephen, Pandit, Jayvardhan, Rogers, Bruce N, Samad, Tarek A, Shaffer, Christopher L, da Silva, Rafael G, Uccello, Daniel P, Webb, Damien, Brodney, Michael A
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Fluorophosphonates on‐Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis
Dutra, Jason K., Foley, Timothy L., Huang, Zhen, Fisher, Ethan L., Lachapelle, Erik A., Mahapatra, Subham, Ogilvie, Kevin, Butler, Todd W., Bellenger, Justin, Devraj Majmudar, Jaimeen, am Ende, Christopher W.
Published in Chembiochem : a European journal of chemical biology (14.05.2021)
Published in Chembiochem : a European journal of chemical biology (14.05.2021)
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Structural basis of the acyl-transfer mechanism of human GPAT1
Johnson, Zachary Lee, Ammirati, Mark, Wasilko, David Jonathan, Chang, Jeanne S, Noell, Stephen, Foley, Timothy L, Yoon, Hyejin, Smith, Kathleen, Asano, Shoh, Hales, Katherine, Wan, Min, Yang, Qingyi, Piotrowski, Mary A, Farley, Kathleen A, Gilbert, Tamara, Aschenbrenner, Lisa M, Fennell, Kimberly F, Dutra, Jason K, Xu, Mary, Guo, Chunyang, Varghese, Alison E, Bellenger, Justin, Quinn, Alandra, Am Ende, Christopher W, West, Graham M, Griffor, Matthew C, Bennett, Donald, Calabrese, Matthew, Steppan, Claire M, Han, Seungil, Wu, Huixian
Published in Nature structural & molecular biology (01.01.2023)
Published in Nature structural & molecular biology (01.01.2023)
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Journal Article
Covalent Small Molecule Inhibitors of Ca2+-Bound S100B
Cavalier, Michael C, Pierce, Adam D, Wilder, Paul T, Alasady, Milad J, Hartman, Kira G, Neau, David B, Foley, Timothy L, Jadhav, Ajit, Maloney, David J, Simeonov, Anton, Toth, Eric A, Weber, David J
Published in Biochemistry (Easton) (28.10.2014)
Published in Biochemistry (Easton) (28.10.2014)
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Journal Article
4‑(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)‑N‑(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a Potent Inhibitor of Bacterial Phosphopantetheinyl Transferase That Attenuates Secondary Metabolism and Thwarts Bacterial Growth
Foley, Timothy L, Rai, Ganesha, Yasgar, Adam, Daniel, Thomas, Baker, Heather L, Attene-Ramos, Matias, Kosa, Nicolas M, Leister, William, Burkart, Michael D, Jadhav, Ajit, Simeonov, Anton, Maloney, David J
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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