Optimizing FOLFIRINOX tolerability in patients with colorectal cancer through dosing irinotecan in the morning for men and in the afternoon for women
Levi, Francis, Ballesta, Annabelle, Karaboué, Abdoulaye, Huang, Qi, Focan, C. N. J., Chollet, Philippe, Bouchahda, Mohamed, Adam, Rene, Garufi, Carlo, Innominato, Pasquale
Published in Journal of clinical oncology (01.02.2020)
Published in Journal of clinical oncology (01.02.2020)
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Journal Article
General practitioner contacts, hospitalizations, and nursing home transfers in older patients up to three years after new cancer diagnosis: Results from a large data linkage cohort study
Depoorter, Victoria, Vanschoenbeek, Katrijn, Decoster, Lore, De Schutter, Harlinde, Debruyne, Philip R., DeGroof, Inge, Bron, Dominique, Cornélis, Frank, Luce, Sylvie, Focan, C. N. J., Verschaeve, Vincent, Debugne, Gwenaelle, Langenaeken, Christine M. L. H., Van Den Bulck, Heidi, Goeminne, Jean-Charles, Milisen, Koen, Flamaing, Johan, Kenis, Cindy, Verdoodt, Freija, Wildiers, Hans
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Pharmacogenomic determinants of cetuximab and oxaliplatin pharmacokinetics during combined intravenous cetuximab (IV-Cet) and triplet hepatic artery chronomodulated infusion in patients (pts) with initially unresectable liver metastases from colorectal cancer (uLM-CRC) (EU OPTILIV trial)
Karaboue, Abdoulaye, Saffroy, Raphael, Desterke, Christophe, Bouchahda, Mohamed, Innominato, Pasquale, Focan, C. N. J., Chatelut, Etienne, Paintaud, Gilles, Milano, Gerard A., Lemoine, Antoinette, Levi, Francis
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Relations between clinical outcomes and pharmacokinetics of irinotecan, oxaliplatin, and 5-fluorouracil during hepatic artery chronomodulated delivery of intravenous cetuximab in patients with extensive liver metastases from colorectal cancer: A translational study in European trial OPTILIV
Levi, Francis, Karaboué, Abdoulaye, Etienne-Grimaldi, Marie-Christine, Paintaud, Gilles, Focan, C. N. J., Innominato, Pasquale F., Bouchahda, Mohamed, Milano, Gerard, Chatelut, Etienne
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Vitamin K epoxide reductase complex subunit 1 (VKORC1): A pharmacogenomic predictor of response and survival in patients (pts) on triplet hepatic artery infusion (HAI) and intravenous cetuximab (IV-Cet) for initially unresectable liver metastases from colorectal cancer (uLM-CRC) (EU trial OPTILIV)
Levi, Francis, Saffroy, Raphael, Karaboue, Abdoulaye, Desterke, Christophe, Boige, Valerie, Hebbar, Mohamed, Smith, Denis Michel, Bouchahda, Mohamed, Innominato, Pasquale, Taieb, Julien, Carvalho, Carlos, Guimbaud, Rosine, Focan, C. N. J., Ducreux, Michel, Adam, Rene, Lemoine, Antoinette
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Quality of life (QoL) in older patients (pts) with cancer and prognostic factors for QoL decline
Decoster, Lore, Quinten, Chantal, Kenis, Cindy, Flamaing, Johan, Debruyne, Philip R., DeGroof, Inge, Focan, C. N. J., Cornelis, Frank, Verschaeve, Vincent, Bachmann, Christian, Bron, Dominique, Luce, Sylvie, Debugne, Gwenaelle, Van Den Bulck, Heidi, Goeminne, Jean Charles, Schrijvers, Dirk L., Lobelle, Jean Pierre, Lycke, Michelle, Milisen, Koen, Wildiers, Hans
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Adherence to geriatric assessment (GA)-based recommendations in older patients (pts) with cancer
Decoster, Lore, Kenis, Cindy, Flamaing, Johan, DeBruyne, Philip, DeGroof, Inge, Focan, C. N. J., Cornelis, Frank, Verschaeve, Vincent, Vanoverbeke, Karen, Libert, Yves, Luce, Sylvie, Nols, Nathalie, Van Den Bulck, Heidi, Goeminne, Jean Charles, Baitar, Abdelbari, Geboers, Katrien, Lobelle, Jean Pierre, Milisen, Koen, Wildiers, Hans
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Impact of early tumor response on prognostic of patients with unresectable liver metastases from wt-KRAS colorectal cancer (LM-CRC) treated with hepatic artery infusion of irinotecan, 5-fluorouracil and oxaliplatin plus intravenous cetuximab after failure of systemic chemotherapy (European Phase II OPTILIV)
Bouchahda, Mohamed, Boige, Valerie, Smith, Denis Michel, Karaboué, Abdoulaye, Hebbar, Mohamed, Lepère, Céline, Focan, C. N. J., Guimbaud, Rosine, Innominato, Pasquale F., Awad, Sameh, Carvalho, Carlos, Tumolo, Salvatore, Truant, Stephanie, De Baere, Thierry, Castaing, Denis, Rougier, Philippe, Taïeb, Julien, Morere, Jean F., Ducreux, Michel, Levi, Francis
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Journal Article
Constitutive single nucleotide polymorphisms (SNP) assessment for predicting tolerability and efficacy of triplet hepatic artery infusion (HAI) and intravenous cetuximab (IV-CET) in patients (pts) with liver metastases from colorectal cancer (LM-CRC) (European trial OPTILIV, NCT00852228)
Levi, Francis, Karaboué, Abdoulaye, Saffroy, Raphaël, Peyric, Elodie, Ducreux, Michel, Smith, Denis Michel, Hebbar, Mohamed, Innominato, Pasquale F., Pernot, Simon, Carvalho, Carlos, Guimbaud, Rosine, Focan, C. N. J., Bouchahda, Mohamed, Adam, Rene, Etienne-Grimaldi, Marie-Christine, Milano, Gerard A., Lemoine, Antoinette
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
Circadian rest-activity rhythm as a predictor of survival in metastatic colorectal cancer
Spiegel, David, Dugué, Pierre-Antoine, Innominato, Pasquale F., Karaboué, Abdoulaye, Dispersyn, Garance, Parganiha, Arti, Giacchetti, Sylvie, Moreau, Thierry, Focan, C. N. J., Waterhouse, Jim, Levi, Francis
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
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Journal Article
Chronomodulated hepatic artery infusion (HAI) of irinotecan, 5-fluorouracil (5-FU), and oxaliplatin (l-OHP) plus intravenous (iv) cetuximab (Cet) (Chrono-Optiliv) in patients with unresectable liver metastases from wt KRAS colorectal cancer (LM-CRC) after treatment failure (European Phase II trial NCT 00852228)
Bouchahda, Mohamed, Karaboué, Abdoulaye, Etienne-Grimaldi, Marie-Christine, Chatelut, Etienne, Innominato, Pasquale F., Paintaud, Gilles, Ricca, Luana, Vibert, Eric, Ajavon, Yves, Awad, Sameh, Castaing, Denis, Focan, C. N. J., Milano, Gerard, Morere, Jean Francois, Adam, Rene, Levi, Francis
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
Four-year survival in patients (pts) undergoing liver surgery after neoadjuvant triplet hepatic artery infusion (HAI) and intravenous cetuximab (IV-CET) for previously treated and unresectable liver metastases from kras wt colorectal cancer (LM-CRC) (European trial OPTILIV, NCT00852228)
Levi, Francis, Ducreux, Michel, Smith, Denis Michel, Hebbar, Mohamed, Lepère, Céline, Focan, C. N. J., Guimbaud, Rosine, Innominato, Pasquale F., Carvalho, Carlos, Tumolo, Salvatore, Truant, Stephanie, Castaing, Denis, Karaboué, Abdoulaye, Boige, Valerie, Bouchahda, Mohamed, Rougier, Philippe, Adam, Rene
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
First European phase II trial of intravenous (iv) cetuximab (Cet) and hepatic artery infusion (HAI) of irinotecan, 5-fluorouracil and oxaliplatin in patients with unresectable liver metastases from wt KRAS colorectal cancer (CRC) after systemic therapy failure (OPTILIV, NCT00852228)
Levi, Francis, Ducreux, Michel, Hebbar, Mohamed, Rougier, Philippe, Focan, C. N. J., Guimbaud, Rosine, Carvalho, Carlos, Tumolo, Salvatore, Innominato, Pasquale F., Ajavon, Yves, Castaing, Denis, De Baere, Thierry, Karaboué, Abdoulaye, Lepere, Celine, Boige, Valerie, Proux, Laetitia, Adam, Rene, Bouchahda, Mohamed
Published in Journal of clinical oncology (20.05.2012)
Published in Journal of clinical oncology (20.05.2012)
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Journal Article
Chemotherapy-induced neutropenia (neutro) association with survival in metastatic colorectal cancer (MCC): Schedule dependency
Innominato, P. F., Giacchetti, S., Småland, R., Focan, C. N. J., Garufi, C., Bjarnason, G. A., Iacobelli, S., Tumolo, S., Karaboué, A., Levi, F.
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Journal Article
Hepatic artery infusion (HAI) of irinotecan, 5-fluorouracil, and oxaliplatin plus intravenous cetuximab (Cet) (Optiliv) after failure on one versus two or three chemotherapy protocols in patients (pts) with unresectable liver metastases from wt KRAS colorectal cancer (LM-CRC) (European phase II clinical trial NCT00852228)
Ducreux, Michel, Innominato, Pasquale F., Hebbar, Mohamed, Smith, Denis Michel, Lepère, Céline, Focan, C. N. J., Guimbaud, Rosine, Carvalho, Carlos, Tumolo, Salvatore, Awad, Sameh, Truant, Stephanie, Castaing, Denis, Karaboué, Abdoulaye, De Baere, Thierry, Kunstlinger, Francis, Bouchahda, Mohamed, Boige, Valerie, Rougier, Philippe, Adam, Rene, Levi, Francis
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
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Journal Article
Circadian robustness as an independent predictor of prolonged progression-free survival (PFS) and overall survival (OS) in 436 patients with metastatic colorectal cancer (mCRC)
Levi, Francis, Parganiha, Arti, Karaboué, Abdoulaye, Innominato, Pasquale F., Giacchetti, Sylvie, Garufi, Carlo, Dispersyn, Garance, Focan, C. N. J., Iacobelli, Stefano, Bjarnason, Georg A, Moreau, Thierry, Dugue, Pierre Antoine, Waterhouse, Jim
Published in Journal of clinical oncology (01.02.2012)
Published in Journal of clinical oncology (01.02.2012)
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Journal Article
Chemotherapy-induced neutropenia association with survival in metastatic colorectal cancer (MCC): Schedule dependency
Innominato, P. F., Giacchetti, S., Smaaland, R., Focan, C. N., Garufi, C., Bjarnason, G. A., Iacobelli, S., Tumolo, S., Karaboué, A., Levi, F.
Published in Journal of clinical oncology (01.02.2011)
Published in Journal of clinical oncology (01.02.2011)
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Journal Article
Final results of first European phase II trial of intravenous cetuximab (Cet) and hepatic artery infusion of irinotecan, 5-fluorouracil, and oxaliplatin in patients (pts) with unresectable liver metastases from wt KRAS colorectal cancer (LM-CRC) after systemic treatment failure (OPTILIV, NCT00852228)
Levi, Francis, Boige, Valerie, Hebbar, Mohamed, Smith, Denis, Lepère, Céline, Focan, C. N. J., Guimbaud, Rosine, Carvalho, Carlos, Tumolo, Salvatore, Innominato, Pasquale F., Ajavon, Yves, Truant, Stephanie, Castaing, Denis, De Baere, Thierry, Kunstlinger, Francis, Karaboué, Abdoulaye, Bouchahda, Mohamed, Rougier, Philippe R, Adam, Rene, Ducreux, Michel
Published in Journal of clinical oncology (01.02.2013)
Published in Journal of clinical oncology (01.02.2013)
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Journal Article
Safety and efficacy of neoadjuvant combination of hepatic artery infusion (HAI) of irinotecan, 5-fluorouracil, and oxaliplatin with intravenous (iv) cetuximab in patients with unresectable liver metastases from colorectal cancer (CRC): Interim report from OPTILIV—A European multicenter phase II trial
Ducreux, M., Rougier, P., Smith, D., Focan, C. N. J., Innominato, P. F., Bouchahda, M., Ajavon, Y., Castaing, D., De Baere, T., Karaboué, A., Lepere, C., Boige, V., Adam, R., Levi, F.
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Journal Article
Optimal control of liver metastases with intravenous cetuximab and hepatic artery infusion of three-drug chemotherapy in patients with liver-only metastases from colorectal cancer: A European multicenter phase II trial
Levi, F., Bouchahda, M., Ducreux, M., Karaboué, A., Focan, C. N., Rougier, P., Innominato, P., Smith, D., Awad, S., Adam, R.
Published in Journal of clinical oncology (20.05.2010)
Published in Journal of clinical oncology (20.05.2010)
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