The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling
Su, Xinming, Floyd, Desiree H, Hughes, Alun, Xiang, Jingyu, Schneider, Jochen G, Uluckan, Ozge, Heller, Emanuela, Deng, Hongju, Zou, Wei, Craft, Clarissa S, Wu, Kaiming, Hirbe, Angela C, Grabowska, Dorota, Eagleton, Mark C, Townsley, Sarah, Collins, Lynne, Piwnica-Worms, David, Steinberg, Thomas H, Novack, Deborah V, Conley, Pamela B, Hurchla, Michelle A, Rogers, Michael, Weilbaecher, Katherine N
Published in The Journal of clinical investigation (01.10.2012)
Published in The Journal of clinical investigation (01.10.2012)
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Journal Article
The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors
Kefas, Benjamin, Comeau, Laurey, Floyd, Desiree H, Seleverstov, Oleksandr, Godlewski, Jakub, Schmittgen, Tom, Jiang, Jinmai, diPierro, Charles G, Li, Yunqing, Chiocca, E. Antonio, Lee, Jeongwu, Fine, Howard, Abounader, Roger, Lawler, Sean, Purow, Benjamin
Published in The Journal of neuroscience (02.12.2009)
Published in The Journal of neuroscience (02.12.2009)
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Journal Article
Interstitial flow differentially increases patient-derived glioblastoma stem cell invasion via CXCR4, CXCL12, and CD44-mediated mechanisms
Kingsmore, Kathryn M, Logsdon, Daniel K, Floyd, Desiree H, Peirce, Shayn M, Purow, Benjamin W, Munson, Jennifer M
Published in Integrative biology (Cambridge) (05.12.2016)
Published in Integrative biology (Cambridge) (05.12.2016)
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Journal Article
Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers
Dominguez, Charli L, Floyd, Desiree H, Xiao, Aizhen, Mullins, Garrett R, Kefas, Benjamin A, Xin, Wenjun, Yacur, Melissa N, Abounader, Roger, Lee, Jae K, Wilson, Gabriela Mustata, Harris, Thurl E, Purow, Benjamin W
Published in Cancer discovery (01.07.2013)
Published in Cancer discovery (01.07.2013)
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Journal Article
A miR-297/hypoxia/DGK-α axis regulating glioblastoma survival
Kefas, Benjamin, Floyd, Desiree H, Comeau, Laurey, Frisbee, Alyse, Dominguez, Charli, Dipierro, Charles G, Guessous, Fadila, Abounader, Roger, Purow, Benjamin
Published in Neuro-oncology (Charlottesville, Va.) (01.12.2013)
Published in Neuro-oncology (Charlottesville, Va.) (01.12.2013)
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Journal Article
Frizzled receptors signal through G proteins
Nichols, Andrea S., Floyd, Desiree H., Bruinsma, Stephen P., Narzinski, Kirk, Baranski, Thomas J.
Published in Cellular signalling (01.06.2013)
Published in Cellular signalling (01.06.2013)
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Journal Article
Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch
Floyd, Desiree H, Kefas, Benjamin, Seleverstov, Oleksandr, Mykhaylyk, Olga, Dominguez, Charli, Comeau, Laurey, Plank, Christian, Purow, Benjamin
Published in Neuro-oncology (Charlottesville, Va.) (01.10.2012)
Published in Neuro-oncology (Charlottesville, Va.) (01.10.2012)
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Journal Article
The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts
Hirbe, Angela C, Roelofs, Anke J, Floyd, Desiree H, Deng, Hongju, Becker, Stephanie N, Lanigan, Lisa G, Apicelli, Anthony J, Xu, Zhiqiang, Prior, Julie L, Eagleton, Mark C, Piwnica-Worms, David, Rogers, Michael J, Weilbaecher, Katherine
Published in Bone (New York, N.Y.) (01.05.2009)
Published in Bone (New York, N.Y.) (01.05.2009)
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Journal Article
APT102, a novel adpase, cooperates with aspirin to disrupt bone metastasis in mice
Uluçkan, Özge, Eagleton, Mark C., Floyd, Desiree H., Morgan, Elizabeth A., Hirbe, Angela C., Kramer, Matthew, Dowland, Nikki, Prior, Julie L., Piwnica-Worms, David, Jeong, Soon Seog, Chen, Ridong, Weilbaecher, Katherine
Published in Journal of cellular biochemistry (01.07.2008)
Published in Journal of cellular biochemistry (01.07.2008)
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Journal Article
Interferon-γ Targets Cancer Cells and Osteoclasts to Prevent Tumor-associated Bone Loss and Bone Metastases
Xu, Zhiqiang, Hurchla, Michelle A., Deng, Hongju, Uluçkan, Özge, Bu, Fang, Berdy, Andrew, Eagleton, Mark C., Heller, Emanuela A., Floyd, Desiree H., Dirksen, Wessel P., Shu, Sherry, Tanaka, Yuetsu, Fernandez, Soledad A., Rosol, Thomas J., Weilbaecher, Katherine N.
Published in The Journal of biological chemistry (13.02.2009)
Published in The Journal of biological chemistry (13.02.2009)
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Journal Article
C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast
Floyd, Desiree H, Geva, Adi, Bruinsma, Stephen P, Overton, Mark C, Blumer, Kendall J, Baranski, Thomas J
Published in The Journal of biological chemistry (12.09.2003)
Published in The Journal of biological chemistry (12.09.2003)
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Journal Article
C5a Receptor Oligomerization
Floyd, Desiree H., Geva, Adi, Bruinsma, Stephen P., Overton, Mark C., Blumer, Kendall J., Baranski, Thomas J.
Published in The Journal of biological chemistry (12.09.2003)
Published in The Journal of biological chemistry (12.09.2003)
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Journal Article
Abstract 3316: An alpha-secretase inhibitor decreases glioma stem cell growth by inhibiting the Notch pathway and LMW Cyclin E
Floyd, Desiree H., Kefas, Benjamin, Seleverstov, Olexsandr, Dominguez, Charli, Comeau, Laurey, Purow, Benjamin W.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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Journal Article
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling
Su, Xinming, Floyd, Desiree H, Hughes, Alun, Schneider, Jochen G, Uluckan, Ozge, Heller, Emanuela, Deng, Hongju, Zou, Wei, Craft, Clarissa S, Wu, Kaiming, Hirbe, Angela C, Grabowska, Dorota, Eagleton, Mark C, Townsley, Sarah, Collins, Lynne, Piwnica-Worms, David, Steinberg, Thomas H, Novack, Deborah V, Conley, Pamela B, Hurchla, Michelle A, Rogers, Michael, Weilbaecherl, Katherine N
Published in The Journal of clinical investigation (01.10.2012)
Published in The Journal of clinical investigation (01.10.2012)
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Journal Article
Interferon-{gamma} Targets Cancer Cells and Osteoclasts to Prevent Tumor-associated Bone Loss and Bone Metastases
Xu, Zhiqiang, Hurchla, Michelle A, Deng, Hongju, Uluckan, Ozge, Bu, Fang, Berdy, Andrew, Eagleton, Mark C, Heller, Emanuela A, Floyd, Desiree H, Dirksen, Wessel P, Shu, Sherry, Tanaka, Yuetsu, Fernandez, Soledad A, Rosol, Thomas J, Weilbaecher, Katherine N
Published in The Journal of biological chemistry (13.02.2009)
Published in The Journal of biological chemistry (13.02.2009)
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Journal Article
Interferon-γ Targets Cancer Cells and Osteoclasts to Prevent Tumor-associated Bone Loss and Bone MetastasesS
Xu, Zhiqiang, Hurchla, Michelle A., Deng, Hongju, Uluçkan, Özge, Bu, Fang, Berdy, Andrew, Eagleton, Mark C., Heller, Emanuela A., Floyd, Desiree H., Dirksen, Wessel P., Shu, Sherry, Tanaka, Yuetsu, Fernandez, Soledad A., Rosol, Thomas J., Weilbaecher, Katherine N.
Published in The Journal of biological chemistry (13.02.2009)
Published in The Journal of biological chemistry (13.02.2009)
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Journal Article
Interferon-γ Targets Cancer Cells and Osteoclasts to Prevent Tumor-associated Bone Loss and Bone Metastases
Zhiqiang Xu, Michelle A. Hurchla, Hongju Deng, Ãzge Uluçkan, Fang Bu, Andrew Berdy, Mark C. Eagleton, Emanuela A. Heller, Desiree H. Floyd, Wessel P. Dirksen, Sherry Shu, Yuetsu Tanaka, Soledad A. Fernandez, Thomas J. Rosol, Katherine N. Weilbaecher
Published in The Journal of biological chemistry (13.02.2009)
Published in The Journal of biological chemistry (13.02.2009)
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Journal Article