Wild-type microglia do not reverse pathology in mouse models of Rett syndrome
Wang, Jieqi, Wegener, Jan Eike, Huang, Teng-Wei, Sripathy, Smitha, De Jesus-Cortes, Hector, Xu, Pin, Tran, Stephanie, Knobbe, Whitney, Leko, Vid, Britt, Jeremiah, Starwalt, Ruth, McDaniel, Latisha, Ward, Chris S, Parra, Diana, Newcomb, Benjamin, Lao, Uyen, Nourigat, Cynthia, Flowers, David A, Cullen, Sean, Jorstad, Nikolas L, Yang, Yue, Glaskova, Lena, Vingeau, Sébastien, Vigneau, Sebastian, Kozlitina, Julia, Yetman, Michael J, Jankowsky, Joanna L, Reichardt, Sybille D, Reichardt, Holger M, Gärtner, Jutta, Bartolomei, Marisa S, Fang, Min, Loeb, Keith, Keene, C Dirk, Bernstein, Irwin, Goodell, Margaret, Brat, Daniel J, Huppke, Peter, Neul, Jeffrey L, Bedalov, Antonio, Pieper, Andrew A
Published in Nature (London) (21.05.2015)
Published in Nature (London) (21.05.2015)
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TALEN-Mediated Gene Editing of HBG in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction
Lux, Christopher T, Pattabhi, Sowmya, Berger, Mason, Nourigat, Cynthia, Flowers, David A, Negre, Olivier, Humbert, Olivier, Yang, Julia G, Lee, Calvin, Jacoby, Kyle, Bernstein, Irwin, Kiem, Hans-Peter, Scharenberg, Andrew, Rawlings, David J
Published in Molecular therapy. Methods & clinical development (15.03.2019)
Published in Molecular therapy. Methods & clinical development (15.03.2019)
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Comparison of dose selection based on target engagement versus inhibition of receptor–ligand interaction for checkpoint inhibitors
Head, Sarah A., Johnson, Carter, Sarkar, Saheli, Matteson, Andrew, Marcantonio, Diana H., Hua, Fei, Burke, John M., Apgar, Joshua F., Flowers, David
Published in CPT: pharmacometrics and systems pharmacology (01.06.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2024)
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227 A computational semi-mechanistic pharmacology model of ATG101, a PD-L1/4–1BB bispecific antibody for treatment of solid tumors and NHL
Flowers, David, Presler, Marc, Subramanian, Kas, Yuraszeck, Theresa, Yuwen, Hui, Hou, Bing, Hoenemann, Dirk
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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CD33 expression and P-glycoprotein–mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy
Walter, Roland B., Gooley, Ted A., van der Velden, Vincent H.J., Loken, Michael R., van Dongen, Jacques J.M., Flowers, David A., Bernstein, Irwin D., Appelbaum, Frederick R.
Published in Blood (15.05.2007)
Published in Blood (15.05.2007)
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Gemtuzumab Ozogamicin, A Potent and Selective Anti-CD33 Antibody−Calicheamicin Conjugate for Treatment of Acute Myeloid Leukemia
Hamann, Philip R, Hinman, Lois M, Hollander, Irwin, Beyer, Carl F, Lindh, Delores, Holcomb, Ryan, Hallett, William, Tsou, Hwei-Ru, Upeslacis, Janis, Shochat, Dan, Mountain, Andrew, Flowers, David A, Bernstein, Irwin
Published in Bioconjugate chemistry (01.01.2002)
Published in Bioconjugate chemistry (01.01.2002)
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An Anti-CD33 Antibody−Calicheamicin Conjugate for Treatment of Acute Myeloid Leukemia. Choice of Linker
Hamann, Philip R, Hinman, Lois M, Beyer, Carl F, Lindh, Delores, Upeslacis, Janis, Flowers, David A, Bernstein, Irwin
Published in Bioconjugate chemistry (01.01.2002)
Published in Bioconjugate chemistry (01.01.2002)
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Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling
Varnum-Finney, B, Wu, L, Yu, M, Brashem-Stein, C, Staats, S, Flowers, D, Griffin, J D, Bernstein, I D
Published in Journal of cell science (01.12.2000)
Published in Journal of cell science (01.12.2000)
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Journal Article
Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome
Wang, Jieqi, Wegener, Jan Eike, Huang, Teng-Wei, Sripathy, Smitha, De Jesus-Cortes, Hector, Xu, Pin, Tran, Stephanie, Knobbe, Whitney, Leko, Vid, Britt, Jeremiah, Starwalt, Ruth, McDaniel, Latisha, Ward, Chris S, Parra, Diana, Newcomb, Benjamin, Lao, Uyen, Nourigat, Cynthia, Flowers, David A, Cullen, Sean, Jorstad, Nikolas L, Yang, Yue, Glaskova, Lena, Vigneau, Sébastien, Kozlitina, Julia, Yetman, Michael J, Jankowsky, Joanna L, Reichardt, Sybille D, Reichardt, Holger M, Gärtner, Jutta, Bartolomei, Marisa S, Fang, Min, Loeb, Keith, Keene, C Dirk, Bernstein, Irwin, Goodell, Margaret, Brat, Daniel J, Huppke, Peter, Neul, Jeffrey L, Bedalov, Antonio, Pieper, Andrew A
Published in Nature (London) (24.09.2015)
Published in Nature (London) (24.09.2015)
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Journal Article
Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin
Linenberger, Michael L., Hong, Tom, Flowers, David, Sievers, Eric L., Gooley, Ted A., Bennett, John M., Berger, Mark S., Leopold, Lance H., Appelbaum, Frederick R., Bernstein, Irwin D.
Published in Blood (15.08.2001)
Published in Blood (15.08.2001)
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The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells
Varnum-Finney, Barbara, Purton, Louise E., Yu, Monica, Brashem-Stein, Carolyn, Flowers, David, Staats, Steven, Moore, Kateri A., Le Roux, Isabelle, Mann, Robert, Gray, Grace, Artavanis-Tsakonas, Spyros, Bernstein, Irwin D.
Published in Blood (01.06.1998)
Published in Blood (01.06.1998)
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A controlled trial of raloxifene (LY139481) HCl: impact on bone turnover and serum lipid profile in healthy postmenopausal women
Draper, M W, Flowers, D E, Huster, W J, Neild, J A, Harper, K D, Arnaud, C
Published in Journal of bone and mineral research (01.06.1996)
Published in Journal of bone and mineral research (01.06.1996)
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Characterization of Ferroelectric Random Access Memory (FRAM) Storage Capacitors
Hihath, Sahar, Harter, Hannah, Fortier, Jerry, Flowers, David
Published in Microscopy and microanalysis (01.08.2020)
Published in Microscopy and microanalysis (01.08.2020)
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