Target mechanism-based whole-cell screening identifies bortezomib as an inhibitor of caseinolytic protease in mycobacteria
Moreira, Wilfried, Ngan, Grace J Y, Low, Jian Liang, Poulsen, Anders, Chia, Brian C S, Ang, Melgious J Y, Yap, Amelia, Fulwood, Justina, Lakshmanan, Umayal, Lim, Jolander, Khoo, Audrey Y T, Flotow, Horst, Hill, Jeffrey, Raju, Ravikiran M, Rubin, Eric J, Dick, Thomas
Published in mBio (05.05.2015)
Published in mBio (05.05.2015)
Get full text
Journal Article
Isolation and synthesis of falcitidin, a novel myxobacterial-derived acyltetrapeptide with activity against the malaria target falcipain-2
Somanadhan, Brinda, Kotturi, Santosh R, Yan Leong, Chung, Glover, Robert P, Huang, Yicun, Flotow, Horst, Buss, Antony D, Lear, Martin J, Butler, Mark S
Published in Journal of antibiotics (01.05.2013)
Published in Journal of antibiotics (01.05.2013)
Get full text
Journal Article
Identification of Chelerythrine as an Inhibitor of BclXL Function
Chan, Shing-Leng, Lee, Mei Chin, Tan, Kuan Onn, Yang, Lay-Kien, Lee, Alex S.Y., Flotow, Horst, Fu, Nai Yang, Butler, Mark S., Soejarto, Doel D., Buss, Antony D., Yu, Victor C.
Published in The Journal of biological chemistry (06.06.2003)
Published in The Journal of biological chemistry (06.06.2003)
Get full text
Journal Article
Establishment of a novel whole animal HTS technology platform for melioidosis drug discovery
Lakshmanan, Umayal, Yap, Amelia, Fulwood, Justina, Yichun, Li, Hoon, Sim Siew, Lim, Jolander, Ting, Audrey, Sem, Xiao Hui, Kreisberg, Jason F, Tan, Patrick, Tan, Gladys, Flotow, Horst
Published in Combinatorial chemistry & high throughput screening (01.01.2014)
Published in Combinatorial chemistry & high throughput screening (01.01.2014)
Get more information
Journal Article
Overview of high-throughput screening
Entzeroth, Michael, Flotow, Horst, Condron, Peter
Published in Current protocols in pharmacology (01.03.2009)
Published in Current protocols in pharmacology (01.03.2009)
Get more information
Journal Article
Phosphorylation of SLP-76 by the ZAP-70 Protein-tyrosine Kinase Is Required for T-cell Receptor Function
Wardenburg, Juliane Bubeck, Fu, Chong, Jackman, Janet K., Flotow, Horst, Wilkinson, Sandra E., Williams, David H., Johnson, Robin, Kong, Guanghui, Chan, Andrew C., Findell, Paul R.
Published in The Journal of biological chemistry (16.08.1996)
Published in The Journal of biological chemistry (16.08.1996)
Get full text
Journal Article
New Antiinfective and Human 5-HT2 Receptor Binding Natural and Semisynthetic Compounds from the Jamaican Sponge Smenospongia aurea
HU, Jin-Feng, SCHETZ, John A., KELLY, Michelle, PENG, Jiang-Nan, ANG, Kenny K. H., FLOTOW, Horst, LEONG, Chung Yan, NG, Siew Bee, BUSS, Antony D., WILKINS, Scott P., HAMANN, Mark T.
Published in Journal of natural products (Washington, D.C.) (01.04.2002)
Published in Journal of natural products (Washington, D.C.) (01.04.2002)
Get full text
Journal Article
Identification of Molecular Subtypes of Gastric Cancer With Different Responses to PI3-Kinase Inhibitors and 5-Fluorouracil
Lei, Zhengdeng, Tan, Iain Beehuat, Das, Kakoli, Deng, Niantao, Zouridis, Hermioni, Pattison, Sharon, Chua, Clarinda, Feng, Zhu, Guan, Yeoh Khay, Ooi, Chia Huey, Ivanova, Tatiana, Zhang, Shenli, Lee, Minghui, Wu, Jeanie, Ngo, Anna, Manesh, Sravanthy, Tan, Elisabeth, Teh, Bin Tean, So, Jimmy Bok Yan, Goh, Liang Kee, Boussioutas, Alex, Lim, Tony Kiat Hon, Flotow, Horst, Tan, Patrick, Rozen, Steven G
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2013)
Get full text
Journal Article
Generation of Active Bovine Terminal Deoxynucleotidyl Transferase (TdT) in E.coli
Kuan, Wee Liang, Joy, Joma, Mee, Ng Fui, Perlyn, Kwek Zekui, Wen, Then Siew, Nguen, Thuy, James, Joanne, Chai, Elaine, Flotow, Horst, Crasta, Sharon, Chua, Kelvin, Peng, Ng Sok, Hill, Jeffrey
Published in Biochemistry Insights (24.08.2010)
Published in Biochemistry Insights (24.08.2010)
Get full text
Journal Article
Stat5a Serine Phosphorylation
Beuvink, Iwan, Hess, Daniel, Flotow, Horst, Hofsteenge, Jan, Groner, Bernd, Hynes, Nancy E.
Published in The Journal of biological chemistry (07.04.2000)
Published in The Journal of biological chemistry (07.04.2000)
Get full text
Journal Article
Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques
Koh-Stenta, Xiaoying, Joy, Joma, Poulsen, Anders, Li, Rong, Tan, Yvonne, Shim, Yoonjung, Min, Jung-Hyun, Wu, Liling, Ngo, Anna, Peng, Jianhe, Seetoh, Wei Guang, Cao, Jing, Wee, John Liang Kuan, Kwek, Perlyn Zekui, Hung, Alvin, Lakshmanan, Umayal, Flotow, Horst, Guccione, Ernesto, Hill, Jeffrey
Published in Biochemical journal (15.07.2014)
Published in Biochemical journal (15.07.2014)
Get more information
Journal Article
An integrative approach identified genes associated with drug response in gastric cancer
Zhou, Jin, Yong, Wei-Peng, Yap, Chui Sun, Vijayaraghavan, Aadhitthya, Sinha, Rohit Anthony, Singh, Brijesh Kumar, Xiu, Sam, Manesh, Sravanthy, Ngo, Anna, Lim, Andrea, Ang, Carolyn, Xie, Chen, Wong, Foong Ying, Lin, Suling J, Wan, Wei Keat, Tan, Iain Beehuat, Flotow, Horst, Tan, Patrick, Lim, Kiat-Hon, Yen, Paul Michael, Goh, Liang Kee
Published in Carcinogenesis (New York) (01.04.2015)
Published in Carcinogenesis (New York) (01.04.2015)
Get full text
Journal Article
Analysis of p53 binding to DNA by fluorescence imaging microscopy
Ong, Hwee Jing, Siau, Jia Wei, Zhang, Jing Bo, Hong, Minghui, Flotow, Horst, Ghadessy, Farid
Published in Micron (Oxford, England : 1993) (01.09.2012)
Published in Micron (Oxford, England : 1993) (01.09.2012)
Get full text
Journal Article
Abstract 1200: Molecular subtypes of gastric cancer show systematic differences in response to PI3K inhibitors and fluorouracil
Lei, Zengdeng, Deng, Nian Tao, Zouridis, Hermioni, Tan, Iain Beehaut, Ooi, Chia Huey, Ivanova, Tatiana, Zhang, Shenli, Lee, Minghui, Wu, Jeanie, Ngo, Anna, Manesh, Sravanthy, Boussioutas, Alex, Teh, Bin Tean, Goh, Liang Kee, Flotow, Horst, Tan, Patrick, Rozen, Steven G.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Get full text
Journal Article
An Automated High-Content Screening Image Analysis Pipeline for the Identification of Selective Autophagic Inducers in Human Cancer Cell Lines
Kriston-Vizi, Janos, Lim, Ching Aeng, Condron, Peter, Chua, Kelvin, Wasser, Martin, Flotow, Horst
Published in Journal of biomolecular screening (01.08.2010)
Published in Journal of biomolecular screening (01.08.2010)
Get full text
Journal Article
Stat5a serine phosphorylation. Serine 779 is constitutively phosphorylated in the mammary gland, and serine 725 phosphorylation influences prolactin-stimulated in vitro DNA binding activity
Beuvink, I, Hess, D, Flotow, H, Hofsteenge, J, Groner, B, Hynes, N E
Published in The Journal of biological chemistry (07.04.2000)
Published in The Journal of biological chemistry (07.04.2000)
Get full text
Journal Article