Xenobiotic-Metabolizing Enzymes and Transporters in the Normal Human Brain: Regional and Cellular Mapping as a Basis for Putative Roles in Cerebral Function
Dutheil, Fabien, Dauchy, Sandrine, Diry, Monique, Sazdovitch, Véronique, Cloarec, Olivier, Mellottée, Lucille, Bièche, Ivan, Ingelman-Sundberg, Magnus, Flinois, Jean-Pierre, de Waziers, Isabelle, Beaune, Philippe, Declèves, Xavier, Duyckaerts, Charles, Loriot, Marie-Anne
Published in Drug metabolism and disposition (01.07.2009)
Published in Drug metabolism and disposition (01.07.2009)
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IN VITRO METABOLISM OF CHLOROQUINE: IDENTIFICATION OF CYP2C8, CYP3A4, AND CYP2D6 AS THE MAIN ISOFORMS CATALYZING N-DESETHYLCHLOROQUINE FORMATION
PROJEAN, Denis, BAUNE, Bruno, FARINOTTI, Robert, FLINOIS, Jean-Pierre, BEAUNE, Philippe, TABURET, Anne-Marie, DUCHARME, Julie
Published in Drug metabolism and disposition (01.06.2003)
Published in Drug metabolism and disposition (01.06.2003)
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Journal Article
Improvement of Cyclophosphamide Activation by CYP2B6 Mutants: From in Silico to ex Vivo
Nguyen, Thien-An, Tychopoulos, Marina, Bichat, Florence, Zimmermann, Clothilde, Flinois, Jean-Pierre, Diry, Monique, Ahlberg, Emelie, Delaforge, Marcel, Corcos, Laurent, Beaune, Philippe, Dansette, Patrick, André, François, de Waziers, Isabelle
Published in Molecular pharmacology (01.04.2008)
Published in Molecular pharmacology (01.04.2008)
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Rapamycin inhibits human renal epithelial cell proliferation: Effect on cyclin D3 mRNA expression and stability
Pallet, Nicolas, Thervet, Eric, Le Corre, Delphine, Knebelmann, Bertrand, Nusbaum, Patrick, Tomkiewicz, Celine, Meria, Paul, Flinois, Jean-Pierre, Beaune, Philippe, Legendre, Christophe, Anglicheau, Dany
Published in Kidney international (01.06.2005)
Published in Kidney international (01.06.2005)
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Prediction of drug-induced liver injury in humans by using in vitro methods: The case of ximelagatran
Kenne, Kerstin, Skanberg, Inger, Glinghammar, Bjorn, Berson, Alain, Pessayre, Dominique, Flinois, Jean-Pierre, Beaune, Philippe, Edebert, Irene, Pohl, Cecilia Diaz, Carlsson, Stefan, Andersson, Tommy B.
Published in Toxicology in vitro (01.04.2008)
Published in Toxicology in vitro (01.04.2008)
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The human colonic microflora influences the alterations of xenobiotic-metabolizing enzymes by catechins in male F344 rats
Lhoste, E.F, Ouriet, V, Bruel, S, Flinois, J.-P, Brézillon, C, Magdalou, J, Chèze, C, Nugon-Baudon, L
Published in Food and chemical toxicology (01.05.2003)
Published in Food and chemical toxicology (01.05.2003)
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In Vitro Metabolism of Quinidine: The (3S)-3-Hydroxylation of Quinidine Is a Specific Marker Reaction for Cytochrome P-4503A4 Activity in Human Liver Microsomes
Nielsen, T L, Rasmussen, B B, Flinois, J P, Beaune, P, Brosen, K
Published in The Journal of pharmacology and experimental therapeutics (01.04.1999)
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Published in The Journal of pharmacology and experimental therapeutics (01.04.1999)
Journal Article
Constitutive overexpression of immunoidentical forms of PCP-induced Euglena gracilis CYP-450
Barque, Jean-Philippe, Abahamid, Abdelouahab, Flinois, Jean-Pierre, Beaune, Philippe, Bonaly, Jacqueline
Published in Biochemical and biophysical research communications (25.10.2002)
Published in Biochemical and biophysical research communications (25.10.2002)
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Identification of the major human hepatic cytochrome P450 involved in activation and N-dechloroethylation of ifosfamide
Walker, Dianne, Flinois, Jean-Pierre, Monkman, Sophia C., Beloc, Claire, Boddy, Alan V., Cholerton, Suzanne, Daly, Ann K., Lind, Michael J., Andrew D.J., Pearson, Beaune, Philippe H., Idle, Jeffrey R.
Published in Biochemical pharmacology (29.03.1994)
Published in Biochemical pharmacology (29.03.1994)
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Overexpression of glutamine synthetase in human primary liver cancer
Christa, L, Simon, M T, Flinois, J P, Gebhardt, R, Brechot, C, Lasserre, C
Published in Gastroenterology (New York, N.Y. 1943) (01.05.1994)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.1994)
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Human cytochromes P450 expressed in Escherichia coli: production of specific antibodies
Belloc, Claire, Baird, Susan, Cosme, José, Lecoeur, Sylvaine, Gautier, Jean-Charles, Challine, Dominique, De Waziers, Isabelle, Flinois, Jean-Pierre, Beaune, Philippe H.
Published in Toxicology (Amsterdam) (08.01.1996)
Published in Toxicology (Amsterdam) (08.01.1996)
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Journal Article
Halofantrine metabolism in microsomes in man: major role of CYP 3A4 and CYP 3A5
Baune, B, Flinois, J P, Furlan, V, Gimenez, F, Taburet, A M, Becquemont, L, Farinotti, R
Published in Journal of pharmacy and pharmacology (01.04.1999)
Published in Journal of pharmacy and pharmacology (01.04.1999)
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Journal Article
Effects of the bacterial status of rats on the changes in some liver cytochrome P450 (EC 1.14.14.1) apoproteins consequent to a glucosinolate-rich diet
Nugon-Baudon, L., Rabot, S., Flinois, J.-P., Lory, S., Beaune, Ph
Published in British journal of nutrition (01.09.1998)
Published in British journal of nutrition (01.09.1998)
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