Pharmacokinetics and Pharmacodynamic Effects of Nemvaleukin Alfa, a Selective Agonist of the Intermediate-Affinity IL-2 Receptor, in Cynomolgus Monkeys
Lopes, Jared E, Sun, Lei, Flick, Heather L, Murphy, Erin A, Losey, Heather C
Published in The Journal of pharmacology and experimental therapeutics (01.11.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2021)
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Journal Article
ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy
Lopes, Jared E, Fisher, Jan L, Flick, Heather L, Wang, Chunhua, Sun, Lei, Ernstoff, Marc S, Alvarez, Juan C, Losey, Heather C
Published in Journal for immunotherapy of cancer (01.04.2020)
Published in Journal for immunotherapy of cancer (01.04.2020)
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Journal Article
1131 Anti-CLEC2D-TLR9 agonist conjugate binds to and internalizes CLEC2D on myeloid cells, plasmacytoid DCs and B cells leading to robust TLR pathway activation and inflammatory cytokine production
Tabrizi, Siamak, Nandivada, Vandana, Irvine, Frano, Goshert, Caitlin, Nichols, Kelly, Scanlon, Elizabeth, Huggins, Matthew, Flick, Heather, Tang, Ming, Tan, Seng-Lai, Wang, Xianzhe, Malu, Shruti
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Oral Health on Wheels: A Service Learning Project for Dental Hygiene Students
Flick, Heather, Barrett, Sheri, Carter-Hanson, Carrie
Published in Journal of dental hygiene (01.08.2016)
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Published in Journal of dental hygiene (01.08.2016)
Journal Article
Abstract 4281: Determination of the Relative Potency of a Selective Agonist of the Intermediate-Affinity IL-2 Receptor on Lymphocytes from Human, Cynomolgus Monkey and Mouse
Rosentrater, Emily E., Flick, Heather, Lopes, Jared E., Losey, Heather C., Wang, Chunhua, Alvarez, Juan C.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 2663: Characterization of the pharmacodynamic immune response to a novel immunotherapeutic agent, ALKS 4230, in mice and non-human primates
Lopes, Jared E., Losey, Heather C., Dean, Reginald L., Flick, Heather L., Huff, Michael R., Moroso, Rosemarie A., Sun, Lei, Alvarez, Juan C.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 4280: Utilizing a selective agonist of the intermediate-affinity IL-2 receptor with an improved pharmacokinetic profile leads to an enhanced immunostimulatory response With reduced toxicity in mice
Losey, Heather C., Lopes, Jared E., Dean, Reginald L., Flick, Heather, Gomes, Madison, Huff, Michael R., Moroso, Rosemarie A., Sun, Lei, Wang, Chunhua, Waters, Julie F., Alvarez, Juan C.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Mechanistic Studies of Agmatine Deiminase from Multiple Bacterial Species
Jones, Justin E, Dreyton, Christina J, Flick, Heather, Causey, Corey P, Thompson, Paul R
Published in Biochemistry (Easton) (02.11.2010)
Published in Biochemistry (Easton) (02.11.2010)
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Journal Article
INTERLEUKIN 18 VARIANTS
HU, Yuan, CHAMOUN, Jean, GUREL, Pinar, WHITMORE, Mark, DONG, Jijun, FLICK, Heather
Year of Publication 18.07.2024
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Year of Publication 18.07.2024
Patent
INTERLEUKIN 18 VARIANTS
Dong, Jijun, Gurel, Pinar, Chamoun, Jean, Flick, Heather, Hu, Yuan, Whitmore, Mark
Year of Publication 06.06.2024
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Year of Publication 06.06.2024
Patent
INTERLEUKIN 18 VARIANTS
HU, Yuan, CHAMOUN, Jean, GUREL, Pinar, WHITMORE, Mark, DONG, Jijun, FLICK, Heather
Year of Publication 16.05.2024
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Year of Publication 16.05.2024
Patent