The kinome 'at large' in cancer
Fleuren, Emmy D. G., Zhang, Luxi, Wu, Jianmin, Daly, Roger J.
Published in Nature reviews. Cancer (01.02.2016)
Published in Nature reviews. Cancer (01.02.2016)
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Journal Article
Directing the use of DDR kinase inhibitors in cancer treatment
Brandsma, Inger, Fleuren, Emmy D G, Williamson, Chris T, Lord, Christopher J
Published in Expert opinion on investigational drugs (02.12.2017)
Published in Expert opinion on investigational drugs (02.12.2017)
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Journal Article
ATR Is a Therapeutic Target in Synovial Sarcoma
Jones, Samuel E, Fleuren, Emmy D G, Frankum, Jessica, Konde, Asha, Williamson, Chris T, Krastev, Dragomir B, Pemberton, Helen N, Campbell, James, Gulati, Aditi, Elliott, Richard, Menon, Malini, Selfe, Joanna L, Brough, Rachel, Pettitt, Stephen J, Niedzwiedz, Wojciech, van der Graaf, Winette T A, Shipley, Janet, Ashworth, Alan, Lord, Christopher J
Published in Cancer research (Chicago, Ill.) (15.12.2017)
Published in Cancer research (Chicago, Ill.) (15.12.2017)
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Journal Article
Targeted Therapy-based Combination Treatment in Rhabdomyosarcoma
van Erp, Anke E M, Versleijen-Jonkers, Yvonne M H, van der Graaf, Winette T A, Fleuren, Emmy D G
Published in Molecular cancer therapeutics (01.07.2018)
Published in Molecular cancer therapeutics (01.07.2018)
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Journal Article
Phosphoproteomic Profiling Reveals ALK and MET as Novel Actionable Targets across Synovial Sarcoma Subtypes
Fleuren, Emmy D G, Vlenterie, Myrella, van der Graaf, Winette T A, Hillebrandt-Roeffen, Melissa H S, Blackburn, James, Ma, Xiuquan, Chan, Howard, Magias, Mandy C, van Erp, Anke, van Houdt, Laurens, Cebeci, Sabri A S, van de Ven, Amy, Flucke, Uta E, Heyer, Erin E, Thomas, David M, Lord, Christopher J, Marini, Kieren D, Vaghjiani, Vijesh, Mercer, Tim R, Cain, Jason E, Wu, Jianmin, Versleijen-Jonkers, Yvonne M H, Daly, Roger J
Published in Cancer research (Chicago, Ill.) (15.08.2017)
Published in Cancer research (Chicago, Ill.) (15.08.2017)
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Journal Article
Expression and clinical relevance of MET and ALK in Ewing sarcomas
Fleuren, Emmy D.G., Roeffen, Melissa H.S., Leenders, William P., Flucke, Uta E., Vlenterie, Myrella, Schreuder, Hendrik W., Boerman, Otto C., Graaf, Winette T.A., Versleijen‐Jonkers, Yvonne M.H.
Published in International journal of cancer (15.07.2013)
Published in International journal of cancer (15.07.2013)
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Journal Article
The role of AXL and the in vitro activity of the receptor tyrosine kinase inhibitor BGB324 in Ewing sarcoma
Fleuren, Emmy D G, Hillebrandt-Roeffen, Melissa H S, Flucke, Uta E, Te Loo, D Maroeska W M, Boerman, Otto C, van der Graaf, Winette T A, Versleijen-Jonkers, Yvonne M H
Published in Oncotarget (30.12.2014)
Published in Oncotarget (30.12.2014)
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Journal Article
Theranostic applications of antibodies in oncology
Fleuren, Emmy D.G., Versleijen-Jonkers, Yvonne M.H., Heskamp, Sandra, van Herpen, Carla M.L., Oyen, Wim J.G., van der Graaf, Winette T.A., Boerman, Otto C.
Published in Molecular oncology (01.06.2014)
Published in Molecular oncology (01.06.2014)
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Journal Article
Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development
Fleuren, Emmy D.G., O'Toole, Sandra, Millar, Ewan K., McNeil, Catriona, Lopez‐Knowles, Elena, Boulghourjian, Alice, Croucher, David R., Schramek, Daniel, Brummer, Tilman, Penninger, Josef M., Sutherland, Robert L., Daly, Roger J.
Published in International journal of cancer (15.09.2010)
Published in International journal of cancer (15.09.2010)
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Journal Article
The strength of small: Improved targeting of Insulin-like Growth Factor-1 Receptor (IGF-1R) with F(ab′)2 -R1507 fragments in Ewing sarcomas
Fleuren, Emmy D.G, Versleijen-Jonkers, Yvonne M.H, Heskamp, Sandra, Roeffen, Melissa H.S, Bouwman, Wilbert H, Molkenboer-Kuenen, Janneke D.M, van Laarhoven, Hanneke W.M, Oyen, Wim J.G, Boerman, Otto C, van der Graaf, Winette T.A
Published in European journal of cancer (1990) (01.09.2013)
Published in European journal of cancer (1990) (01.09.2013)
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Journal Article
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer
Wong, Marie, Mayoh, Chelsea, Lau, Loretta M. S., Khuong-Quang, Dong-Anh, Pinese, Mark, Kumar, Amit, Barahona, Paulette, Wilkie, Emilie E., Sullivan, Patricia, Bowen-James, Rachel, Syed, Mustafa, Martincorena, Iñigo, Abascal, Federico, Sherstyuk, Alexandra, Bolanos, Noemi A., Baber, Jonathan, Priestley, Peter, Dolman, M. Emmy M., Fleuren, Emmy D. G., Gauthier, Marie-Emilie, Mould, Emily V. A., Gayevskiy, Velimir, Gifford, Andrew J., Grebert-Wade, Dylan, Strong, Patrick A., Manouvrier, Elodie, Warby, Meera, Thomas, David M., Kirk, Judy, Tucker, Katherine, O’Brien, Tracey, Alvaro, Frank, McCowage, Geoffry B., Dalla-Pozza, Luciano, Gottardo, Nicholas G., Tapp, Heather, Wood, Paul, Khaw, Seong-Lin, Hansford, Jordan R., Moore, Andrew S., Norris, Murray D., Trahair, Toby N., Lock, Richard B., Tyrrell, Vanessa, Haber, Michelle, Marshall, Glenn M., Ziegler, David S., Ekert, Paul G., Cowley, Mark J.
Published in Nature medicine (01.11.2020)
Published in Nature medicine (01.11.2020)
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Journal Article
Systemic Treatment for Adults with Synovial Sarcoma
Desar, Ingrid M. E., Fleuren, Emmy D. G., van der Graaf, Winette T. A.
Published in Current treatment options in oncology (01.02.2018)
Published in Current treatment options in oncology (01.02.2018)
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Journal Article
Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma
Terry, Rachael L., Meyran, Deborah, Fleuren, Emmy D. G., Mayoh, Chelsea, Zhu, Joe, Omer, Natacha, Ziegler, David S., Haber, Michelle, Darcy, Phillip K., Trapani, Joseph A., Neeson, Paul J., Ekert, Paul G.
Published in Cancers (20.09.2021)
Published in Cancers (20.09.2021)
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Journal Article
Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo
van Erp, Anke E. M., van Houdt, Laurens, Hillebrandt-Roeffen, Melissa H. S., van Bree, Niek F. H. N., Flucke, Uta E., Mentzel, Thomas, Shipley, Janet, Desar, Ingrid M. E., Fleuren, Emmy D. G., Versleijen-Jonkers, Yvonne M. H., van der Graaf, Winette T. A.
Published in Journal of cancer research and clinical oncology (01.07.2020)
Published in Journal of cancer research and clinical oncology (01.07.2020)
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Journal Article
Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness
Holme, Harriett, Gulati, Aditi, Brough, Rachel, Fleuren, Emmy D. G., Bajrami, Ilirjana, Campbell, James, Chong, Irene Y., Costa-Cabral, Sara, Elliott, Richard, Fenton, Tim, Frankum, Jessica, Jones, Samuel E., Menon, Malini, Miller, Rowan, Pemberton, Helen N., Postel-Vinay, Sophie, Rafiq, Rumana, Selfe, Joanna L., von Kriegsheim, Alex, Munoz, Amaya Garcia, Rodriguez, Javier, Shipley, Janet, van der Graaf, Winette T. A., Williamson, Chris T., Ryan, Colm J., Pettitt, Stephen, Ashworth, Alan, Strauss, Sandra J., Lord, Christopher J.
Published in Scientific reports (13.07.2018)
Published in Scientific reports (13.07.2018)
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Journal Article
Enhancing the Potential of Immunotherapy in Paediatric Sarcomas: Breaking the Immunosuppressive Barrier with Receptor Tyrosine Kinase Inhibitors
Fleuren, Emmy D G, Terry, Rachael L, Meyran, Deborah, Omer, Natacha, Trapani, Joseph A, Haber, Michelle, Neeson, Paul J, Ekert, Paul G
Published in Biomedicines (30.11.2021)
Published in Biomedicines (30.11.2021)
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