Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility
Blackman, Lewis D, Varlas, Spyridon, Arno, Maria C, Houston, Zachary H, Fletcher, Nicholas L, Thurecht, Kristofer J, Hasan, Muhammad, Gibson, Matthew I, O’Reilly, Rachel K
Published in ACS central science (27.06.2018)
Published in ACS central science (27.06.2018)
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Journal Article
A novel immunomodulating peptide with potential to complement oligodeoxynucleotide-mediated adjuvanticity in vaccination strategies
Agrez, Michael, Chandler, Christopher, Thurecht, Kristofer J., Fletcher, Nicholas L., Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew M., Gooding, Hayley, Gallagher, Laura
Published in Scientific reports (05.11.2024)
Published in Scientific reports (05.11.2024)
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Journal Article
Direct Comparison of Poly(ethylene glycol) and Phosphorylcholine Drug-Loaded Nanoparticles In Vitro and In Vivo
Noy, Janina-Miriam, Chen, Fan, Akhter, Dewan T, Houston, Zachary H, Fletcher, Nicholas L, Thurecht, Kristofer J, Stenzel, Martina H
Published in Biomacromolecules (08.06.2020)
Published in Biomacromolecules (08.06.2020)
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Journal Article
An immunomodulating peptide with potential to suppress tumour growth and autoimmunity
Agrez, Michael, Chandler, Christopher, Thurecht, Kristofer J., Fletcher, Nicholas L., Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Blyth, Benjamin, Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew M., Gooding, Hayley, Gallagher, Laura
Published in Scientific reports (13.11.2023)
Published in Scientific reports (13.11.2023)
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Journal Article
Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation
Jia, Xinying, Chin, Yanni K.-Y., Zhang, Alan H., Crawford, Theo, Zhu, Yifei, Fletcher, Nicholas L., Zhou, Zihan, Hamilton, Brett R., Stroet, Martin, Thurecht, Kristofer J., Mobli, Mehdi
Published in Communications chemistry (04.03.2023)
Published in Communications chemistry (04.03.2023)
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Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies
Houston, Zachary H, Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B, Fletcher, Nicholas L, Fuchs, Adrian V, Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W, Mahler, Stephen M, Richards, Linda J, Caruso, Frank, Thurecht, Kristofer J
Published in ACS central science (27.05.2020)
Published in ACS central science (27.05.2020)
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Journal Article
Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)
Yeh, Mei-Chun, Tse, Brian W. C., Fletcher, Nicholas L., Houston, Zachary H., Lund, Maria, Volpert, Marianna, Stewart, Chelsea, Sokolowski, Kamil A., Jeet, Varinder, Thurecht, Kristofer J., Campbell, Douglas H., Walsh, Bradley J., Nelson, Colleen C., Russell, Pamela J.
Published in EJNMMI research (07.05.2020)
Published in EJNMMI research (07.05.2020)
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Journal Article
The Impact of Polymer Size and Cleavability on the Intravenous Pharmacokinetics of PEG-Based Hyperbranched Polymers in Rats
Marasini, Nirmal, Fu, Changkui, Fletcher, Nicholas L, Subasic, Christopher, Er, Gerald, Mardon, Karine, Thurecht, Kristofer J, Whittaker, Andrew K, Kaminskas, Lisa M
Published in Nanomaterials (Basel, Switzerland) (08.12.2020)
Published in Nanomaterials (Basel, Switzerland) (08.12.2020)
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Journal Article
Characterization of the Biodistribution of a Silica Vesicle Nanovaccine Carrying a Rhipicephalus (Boophilus) microplus Protective Antigen With in vivo Live Animal Imaging
Mody, Karishma T, Zhang, Bing, Li, Xun, Fletcher, Nicholas L, Akhter, Dewan T, Jarrett, Sandy, Zhang, Jun, Yu, Chengzhong, Thurecht, Kristofer J, Mahony, Timothy J, Mitter, Neena
Published in Frontiers in bioengineering and biotechnology (18.01.2021)
Published in Frontiers in bioengineering and biotechnology (18.01.2021)
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Journal Article
Cyanine-5-Driven Behaviours of Hyperbranched Polymers Designed for Therapeutic Delivery Are Cell-Type Specific and Correlated with Polar Lipid Distribution in Membranes
Simpson, Joshua D., Currin-Ross, Denni L., Ediriweera, Gayathri R., Schirra, Horst Joachim, Fletcher, Nicholas L., Bell, Craig A., Arno, Maria C., Thurecht, Kristofer J.
Published in Nanomaterials (Basel, Switzerland) (02.07.2021)
Published in Nanomaterials (Basel, Switzerland) (02.07.2021)
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Journal Article
Engineering Fluorescent Gold Nanoclusters Using Xanthate-Functionalized Hydrophilic Polymers: Toward Enhanced Monodispersity and Stability
Deepagan, Veerasikku Gopal, Leiske, Meike N, Fletcher, Nicholas L, Rudd, David, Tieu, Terence, Kirkwood, Nicholas, Thurecht, Kristofer J, Kempe, Kristian, Voelcker, Nicolas H, Cifuentes-Rius, Anna
Published in Nano letters (13.01.2021)
Published in Nano letters (13.01.2021)
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Journal Article
Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma
Janjua, Taskeen Iqbal, Cao, Yuxue, Ahmed-Cox, Aria, Raza, Aun, Moniruzzaman, Md, Akhter, Dewan Taslima, Fletcher, Nicholas L., Kavallaris, Maria, Thurecht, Kristofer J., Popat, Amirali
Published in Journal of controlled release (01.05.2023)
Published in Journal of controlled release (01.05.2023)
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Journal Article
Mitigating the Effects of Persistent Antipolymer Immune Reactions in Nanomedicine: Evaluating Materials-Based Approaches Using Molecular Imaging
Humphries, James, Fletcher, Nicholas L., Sonderegger, Stefan E., Bell, Craig A., Kempe, Kristian, Thurecht, Kristofer J.
Published in ACS nano (22.07.2024)
Published in ACS nano (22.07.2024)
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Journal Article
Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation
Mills, Jessica A, Liu, Feifei, Jarrett, Thomas R, Fletcher, Nicholas L, Thurecht, Kristofer J
Published in Biomaterials science (14.06.2022)
Published in Biomaterials science (14.06.2022)
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Journal Article
Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures
Pizzi, David, Humphries, James, Morrow, Joshua P., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J., Kempe, Kristian
Published in European polymer journal (01.12.2019)
Published in European polymer journal (01.12.2019)
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Journal Article
Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers
Balaji, Arunpandian, Bell, Craig A., Houston, Zachary H., Bridle, Kim R., Genz, Berit, Fletcher, Nicholas L., Ramm, Grant A., Thurecht, Kristofer J.
Published in Biomaterials (01.11.2023)
Published in Biomaterials (01.11.2023)
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Journal Article
Controlling the Biological Fate of Micellar Nanoparticles: Balancing Stealth and Targeting
Sivaram, Amal J, Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E, Fletcher, Nicholas L, Houston, Zachary H, Howard, Christopher B, Mahler, Stephen M, Alexander, Cameron, Kent, Stephen J, Bell, Craig A, Thurecht, Kristofer J
Published in ACS nano (27.10.2020)
Published in ACS nano (27.10.2020)
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Journal Article
Evaluation of the in vivo fate of ultrapure alginate in a BALB/c mouse model
A, Anitha, Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J., Grøndahl, Lisbeth
Published in Carbohydrate polymers (15.06.2021)
Published in Carbohydrate polymers (15.06.2021)
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