A Single Domain Shark Antibody Targeting the Transferrin Receptor 1 Delivers a TrkB Agonist Antibody to the Brain and Provides Full Neuroprotection in a Mouse Model of Parkinson’s Disease
Clarke, Emily, Stocki, Pawel, Sinclair, Elizabeth H., Gauhar, Aziz, Fletcher, Edward J. R., Krawczun-Rygmaczewska, Alicja, Duty, Susan, Walsh, Frank S., Doherty, Patrick, Rutkowski, Julia Lynn
Published in Pharmaceutics (24.06.2022)
Published in Pharmaceutics (24.06.2022)
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Journal Article
Drug repurposing strategies of relevance for Parkinson’s disease
Fletcher, Edward J. R., Kaminski, Thomas, Williams, Gareth, Duty, Susan
Published in Pharmacology research & perspectives (01.08.2021)
Published in Pharmacology research & perspectives (01.08.2021)
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Journal Article
Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats
Fletcher, Edward J. R., Jamieson, Aran D., Williams, Gareth, Doherty, Patrick, Duty, Susan
Published in Scientific reports (06.06.2019)
Published in Scientific reports (06.06.2019)
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Animal models of Parkinson's disease: a guide to selecting the optimal model for your research
Lama, Joana, Buhidma, Yazead, Fletcher, Edward J R, Duty, Susan
Published in Neuronal signaling (01.12.2021)
Published in Neuronal signaling (01.12.2021)
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Journal Article
TrkB agonist antibody delivery to the brain using a TfR1 specific BBB shuttle provides neuroprotection in a mouse model of Parkinson's Disease
Clarke, Emily, Sinclair, Liz, Fletcher, Edward J R, Krawczun-Rygmaczewska, Alicja, Duty, Susan, Stocki, Pawel, Rutowski, J Lynn, Doherty, Patrick, Walsh, Frank S
Published in bioRxiv (12.03.2020)
Published in bioRxiv (12.03.2020)
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