Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3
Borghesan, Michela, Fafián-Labora, Juan, Eleftheriadou, Olga, Carpintero-Fernández, Paula, Paez-Ribes, Marta, Vizcay-Barrena, Gema, Swisa, Avital, Kolodkin-Gal, Dror, Ximénez-Embún, Pilar, Lowe, Robert, Martín-Martín, Belen, Peinado, Hector, Muñoz, Javier, Fleck, Roland A., Dor, Yuval, Ben-Porath, Ittai, Vossenkamper, Anna, Muñoz-Espin, Daniel, O’Loghlen, Ana
Published in Cell reports (Cambridge) (25.06.2019)
Published in Cell reports (Cambridge) (25.06.2019)
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Cortical wiring by synapse type-specific control of local protein synthesis
Bernard, Clémence, Exposito-Alonso, David, Selten, Martijn, Sanalidou, Stella, Hanusz-Godoy, Alicia, Aguilera, Alfonso, Hamid, Fursham, Oozeer, Fazal, Maeso, Patricia, Allison, Leanne, Russell, Matthew, Fleck, Roland A, Rico, Beatriz, Marín, Oscar
Published in Science (American Association for the Advancement of Science) (25.11.2022)
Published in Science (American Association for the Advancement of Science) (25.11.2022)
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Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
Hervera, Arnau, De Virgiliis, Francesco, Palmisano, Ilaria, Zhou, Luming, Tantardini, Elena, Kong, Guiping, Hutson, Thomas, Danzi, Matt C, Perry, Rotem Ben-Tov, Santos, Celio X C, Kapustin, Alexander N, Fleck, Roland A, Del Río, José Antonio, Carroll, Thomas, Lemmon, Vance, Bixby, John L, Shah, Ajay M, Fainzilber, Mike, Di Giovanni, Simone
Published in Nature cell biology (01.03.2018)
Published in Nature cell biology (01.03.2018)
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A Moving Source of Matrix Components Is Essential for De Novo Basement Membrane Formation
Matsubayashi, Yutaka, Louani, Adam, Dragu, Anca, Sánchez-Sánchez, Besaiz J., Serna-Morales, Eduardo, Yolland, Lawrence, Gyoergy, Attila, Vizcay, Gema, Fleck, Roland A., Heddleston, John M., Chew, Teng-Leong, Siekhaus, Daria E., Stramer, Brian M.
Published in Current biology (20.11.2017)
Published in Current biology (20.11.2017)
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A Distance-Dependent Distribution of Presynaptic Boutons Tunes Frequency-Dependent Dendritic Integration
Grillo, Federico W., Neves, Guilherme, Walker, Alison, Vizcay-Barrena, Gema, Fleck, Roland A., Branco, Tiago, Burrone, Juan
Published in Neuron (Cambridge, Mass.) (25.07.2018)
Published in Neuron (Cambridge, Mass.) (25.07.2018)
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Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?
Awan, Maooz, Buriak, Iryna, Fleck, Roland, Fuller, Barry, Goltsev, Anatoliy, Kerby, Julie, Lowdell, Mark, Mericka, Pavel, Petrenko, Alexander, Petrenko, Yuri, Rogulska, Olena, Stolzing, Alexandra, Stacey, Glyn N
Published in Regenerative medicine (01.03.2020)
Published in Regenerative medicine (01.03.2020)
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De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy
Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-Buniak, Joanna, Valenti, Melanie, Howell, Louise, Fleck, Roland A., Martin, Lesley-Ann, Kirkin, Vladimir, Leach, Martin O., Chung, Yuen-Li
Published in Autophagy (02.06.2020)
Published in Autophagy (02.06.2020)
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Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB)
Sekhar, Gayathri N, Georgian, Ana R, Sanderson, Lisa, Vizcay-Barrena, Gema, Brown, Rachel C, Muresan, Paula, Fleck, Roland A, Thomas, Sarah A
Published in PloS one (31.03.2017)
Published in PloS one (31.03.2017)
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Stall in Canonical Autophagy-Lysosome Pathways Prompts Nucleophagy-Based Nuclear Breakdown in Neurodegeneration
Baron, Olga, Boudi, Adel, Dias, Catarina, Schilling, Michael, Nölle, Anna, Vizcay-Barrena, Gema, Rattray, Ivan, Jungbluth, Heinz, Scheper, Wiep, Fleck, Roland A., Bates, Gillian P., Fanto, Manolis
Published in Current biology (04.12.2017)
Published in Current biology (04.12.2017)
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Hydrophobic Mismatch in the Thylakoid Membrane Regulates Photosynthetic Light Harvesting
Wilson, Sam, Clarke, Charlea D., Carbajal, M. Alejandra, Buccafusca, Roberto, Fleck, Roland A., Daskalakis, Vangelis, Ruban, Alexander V.
Published in Journal of the American Chemical Society (29.05.2024)
Published in Journal of the American Chemical Society (29.05.2024)
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Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
Lussignol, Marion, Kopp, Martina, Molloy, Kelly, Vizcay-Barrena, Gema, Fleck, Roland A., Dorner, Marcus, Bell, Kierstin L., Chait, Brian T., Rice, Charles M., Catanese, Maria Teresa
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.2016)
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Nox4 regulates InsP3 receptor‐dependent Ca2+ release into mitochondria to promote cell survival
Beretta, Matteo, Santos, Celio XC, Molenaar, Chris, Hafstad, Anne D, Miller, Chris CJ, Revazian, Aram, Betteridge, Kai, Schröder, Katrin, Streckfuß‐Bömeke, Katrin, Doroshow, James H, Fleck, Roland A, Su, Tsung‐Ping, Belousov, Vsevolod V, Parsons, Maddy, Shah, Ajay M
Published in The EMBO journal (01.10.2020)
Published in The EMBO journal (01.10.2020)
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Journal Article
Infrared nanoimaging of neuronal ultrastructure and nanoparticle interaction with cells
Greaves, George E, Allison, Leanne, Machado, Pedro, Morfill, Corinne, Fleck, Roland A, Porter, Alexandra E, Phillips, Chris C
Published in Nanoscale (21.03.2024)
Published in Nanoscale (21.03.2024)
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Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress
Hale, Victoria L., Watermeyer, Jean M., Hackett, Fiona, Vizcay-Barrena, Gema, van Ooij, Christiaan, Thomas, James A., Spink, Matthew C., Harkiolaki, Maria, Duke, Elizabeth, Fleck, Roland A., Blackman, Michael J., Saibil, Helen R.
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (28.03.2017)
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Human Mesenchymal Stromal Cells Engineered to Express Collagen VII Can Restore Anchoring Fibrils in Recessive Dystrophic Epidermolysis Bullosa Skin Graft Chimeras
Petrova, Anastasia, Georgiadis, Christos, Fleck, Roland A., Allison, Leanne, McGrath, John A., Dazzi, Francesco, Di, Wei-Li, Qasim, Waseem
Published in Journal of investigative dermatology (01.01.2020)
Published in Journal of investigative dermatology (01.01.2020)
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Characterising the chemical and physical properties of phase-change nanodroplets
Zhang, Weiqi, Metzger, Hilde, Vlatakis, Stavros, Claxton, Amelia, Carbajal, M. Alejandra, Fung, Leong Fan, Mason, James, Chan, K.L. Andrew, Pouliopoulos, Antonios N., Fleck, Roland A., Prentice, Paul, Thanou, Maya
Published in Ultrasonics sonochemistry (01.07.2023)
Published in Ultrasonics sonochemistry (01.07.2023)
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Excitatory and inhibitory synapses show a tight subcellular correlation that weakens over development
Horton, Sally, Mastrolia, Vincenzo, Jackson, Rachel E., Kemlo, Sarah, Pereira Machado, Pedro M., Carbajal, Maria Alejandra, Hindges, Robert, Fleck, Roland A., Aguiar, Paulo, Neves, Guilherme, Burrone, Juan
Published in Cell reports (Cambridge) (23.07.2024)
Published in Cell reports (Cambridge) (23.07.2024)
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Nanostars Carrying Multifunctional Neurotrophic Dendrimers Protect Neurons in Preclinical In Vitro Models of Neurodegenerative Disorders
Morfill, Corinne, Pankratova, Stanislava, Machado, Pedro, Fernando, Nathalie K., Regoutz, Anna, Talamona, Federica, Pinna, Alessandra, Klosowski, Michal, Wilkinson, Robert J., Fleck, Roland A., Xie, Fang, Porter, Alexandra E., Kiryushko, Darya
Published in ACS applied materials & interfaces (26.10.2022)
Published in ACS applied materials & interfaces (26.10.2022)
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DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome
Costa, Alessandro, Renault, Ludovic, Swuec, Paolo, Petojevic, Tatjana, Pesavento, James J, Ilves, Ivar, MacLellan-Gibson, Kirsty, Fleck, Roland A, Botchan, Michael R, Berger, James M
Published in eLife (12.08.2014)
Published in eLife (12.08.2014)
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Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N‑Methyl‑d‑aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro
Valente, Pierluigi, Kiryushko, Darya, Sacchetti, Silvio, Machado, Pedro, Cobley, Claire M., Mangini, Vincenzo, Porter, Alexandra E., Spatz, Joachim P., Fleck, Roland A., Benfenati, Fabio, Fiammengo, Roberto
Published in ACS nano (23.06.2020)
Published in ACS nano (23.06.2020)
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