An Adjuvanted Herpes Simplex Virus 2 Subunit Vaccine Elicits a T Cell Response in Mice and Is an Effective Therapeutic Vaccine in Guinea Pigs
Skoberne, Mojca, Cardin, Rhonda, Lee, Alexander, Kazimirova, Ana, Zielinski, Veronica, Garvie, Danielle, Lundberg, Amy, Larson, Shane, Bravo, Fernando J, Bernstein, David I, Flechtner, Jessica B, Long, Deborah
Published in Journal of Virology (01.04.2013)
Published in Journal of Virology (01.04.2013)
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Distinct effects on diversifying selection by two mechanisms of immunity against Streptococcus pneumoniae
Li, Yuan, Gierahn, Todd, Thompson, Claudette M, Trzciński, Krzysztof, Ford, Christopher B, Croucher, Nicholas, Gouveia, Paulo, Flechtner, Jessica B, Malley, Richard, Lipsitch, Marc
Published in PLoS pathogens (01.11.2012)
Published in PLoS pathogens (01.11.2012)
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Therapeutic Vaccine for Genital Herpes Simplex Virus-2 Infection: Findings From a Randomized Trial
Bernstein, David I., Wald, Anna, Warren, Terri, Fife, Kenneth, Tyring, Stephen, Lee, Patricia, Van Wagoner, Nick, Magaret, Amalia, Flechtner, Jessica B., Tasker, Sybil, Chan, Jason, Morris, Amy, Hetherington, Seth
Published in The Journal of infectious diseases (15.03.2017)
Published in The Journal of infectious diseases (15.03.2017)
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Therapeutic HSV-2 vaccine decreases recurrent virus shedding and recurrent genital herpes disease
Bernstein, David I., Flechtner, Jessica B., McNeil, Lisa K., Heineman, Thomas, Oliphant, Tom, Tasker, Sybil, Wald, Anna, Hetherington, Seth
Published in Vaccine (06.06.2019)
Published in Vaccine (06.06.2019)
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Identification of novel virus-specific antigens by CD4+ and CD8+ T cells from asymptomatic HSV-2 seropositive and seronegative donors
Long, Deborah, Skoberne, Mojca, Gierahn, Todd M, Larson, Shane, Price, Jessica A, Clemens, Veronica, Baccari, Amy E, Cohane, Kenya P, Garvie, Danielle, Siber, George R, Flechtner, Jessica B
Published in Virology (New York, N.Y.) (01.09.2014)
Published in Virology (New York, N.Y.) (01.09.2014)
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Improving Cancer Immunotherapies through Empirical Neoantigen Selection
Nogueira, Catarina, Kaufmann, Johanna K, Lam, Hubert, Flechtner, Jessica B
Published in Trends in cancer (01.02.2018)
Published in Trends in cancer (01.02.2018)
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Development of a high-throughput β-Gal-based neutralization assay for quantitation of herpes simplex virus-neutralizing antibodies in human samples
Baccari, Amy, Cooney, Michael, Blevins, Tamara P, Morrison, Lynda A, Larson, Shane, Skoberne, Mojca, Belshe, Robert B, Flechtner, Jessica B, Long, Deborah
Published in Vaccine (19.07.2016)
Published in Vaccine (19.07.2016)
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Identification of Chlamydia trachomatis Antigens Recognized by T Cells From Highly Exposed Women Who Limit or Resist Genital Tract Infection
Russell, Ali N., Zheng, Xiaojing, O'Connell, Catherine M., Wiesenfeld, Harold C., Hillier, Sharon L., Taylor, Brandie D., Picard, Michelle D., Flechtner, Jessica B., Zhong, Wujuan, Frazer, Lauren C., Darville, Toni
Published in The Journal of infectious diseases (15.12.2016)
Published in The Journal of infectious diseases (15.12.2016)
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High-Affinity Interactions between Peptides and Heat Shock Protein 70 Augment CD8+ T Lymphocyte Immune Responses
Flechtner, Jessica B, Cohane, Kenya Prince, Mehta, Sunil, Slusarewicz, Paul, Leonard, Alexis Kays, Barber, Brian H, Levey, Daniel L, Andjelic, Sofija
Published in The Journal of immunology (1950) (15.07.2006)
Published in The Journal of immunology (1950) (15.07.2006)
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Abstract 1762: InhibigensTM subvert otherwise-efficacious cancer vaccines and immunotherapies in conjunction with alterations in the tumor microenvironment
Starobinets, Hanna, Devault, Victoria L., Rinaldi, Stephanie, Arnold, Julie, Odeh, Osaruese, Nguyen, Cindy, Flechtner, Jessica B., Lam, Hubert
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Inhibigens™ drive pro-tumor responses and may act through non-classical inhibitory mechanisms
DeVault, Victoria L, Starobinets, Hanna, Arnold, Julie, Rinaldi, Stephanie, Odeh, Osaruese, Nguyen, Cindy, Flechtner, Jessica B, Lam, Hubert
Published in The Journal of immunology (1950) (01.05.2021)
Published in The Journal of immunology (1950) (01.05.2021)
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Abstract 6680: Inclusion of inhibitory neoantigens can abolish efficacy of otherwise protective therapeutic anti-tumor vaccines
DeVault, Victoria L., Starobinets, Hanna, Adhikari, Sanmit, Singh, Simran, Rinaldi, Stephanie, Classon, Brendan, Flechtner, Jessica B., Lam, Hubert
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Inhibigens, personal neoantigens that drive suppressive T cell responses, abrogate protection of therapeutic anti-tumor vaccines
DeVault, Victoria L, Starobinets, Hanna, Adhikari, Sanmit, Singh, Simran, Rinaldi, Stephanie, Classon, Brendan, Flechtner, Jessica B., Lam, Hubert
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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Abstract LB-223: ATLASTMreveals a dominant inhibitory antigen in melanoma patients, and a reduced breadth of tumor-associated antigen-specific T cells in non-responders to checkpoint blockade
Dowal, Louisa, Lyubetskaya, Anna, Cabral, Crystal, Croll, Mariya, Warren, Christopher, Perry, James, Hayes, Melissa, Loizeaux, James, Foti, James, Flechtner, Jessica B., Dobson, Jason R., Hodi, F. Stephen, Broom, Wendy
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 5718: Ex vivo ATLAS-identification of neoantigens for personalized cancer immunotherapy in mouse melanoma
Starobinets, Hanna, Nogueira, Catarina, Ferber, Kyle, Xu, Huilei, Dhaneshwar, Abha, Dobson, Jason R., Loizeaux, James, Foti, James, O'Keefe, Michael, Donis, Erick, Broom, Wendy, Carroll, Pamela, Kirschmeier, Paul, Flechtner, Jessica B., Lam, Hubert
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 730: Neoantigen identification using the ATLAS T cell profiling platform highlights the need to empirically define neoantigens
Dobson, Jason, Xu, Huilei, Kaufmann, Johanna, Foti, James, Yuan, Jin, O''Keeffe, Michael, Cabral, Crystal, Loizeaux, James, Warren, Christopher, Wu, Ning, Donis, Erick, Ferber, Kyle, Carroll, Pamela, Flechtner, Jessica B., Broom, Wendy
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 632: Genome-scale neoantigen screening using ATLAS™ prioritizes candidate antigens for immunotherapy in a non-small cell lung cancer patient
Ghamsari, Lila, Flano, Emilio, Jacques, Judy, Liu, Biao, Yan, Zheng, Alami, Aula, Kelley, Christine, Zhang, Theresa, Havel, Jonathan, Makarov, Vladimir, Merghoub, Taha, Wolchok, Jedd D., Hellman, Matthew, Carroll, Pamela, Chan, Timothy, Flechtner, Jessica B.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
The immunotherapeutic GEN-003 as a prophylactic vaccine candidate for genital herpes in guinea pigs
Kaufmann, Johanna K, Cardin, Rhonda D, O’Keeffe, Michael, Baccari, Amy, Le, Bonnie, Sanz, Vinny, Yu, David, Flechtner, Jessica B, Flano, Emilio, Bernstein, David I
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Systematic analysis of T cell responses specific to the Epstein-Barr virus proteome using ATLAS
Kaufmann, Johanna K, Liu, Biao, Jacques, Judy, Wu, Ning, Yan, Zheng, Alami, Aula, Kelley, Christine, O’Keeffe, Michael S, Hoover, Maegan E, McManus, Margaret M, Henderson, Jennifer, Ghamsari, Lila, Olivieri, Kevin C, Flechtner, Jessica B, Broom, Wendy, Flano, Emilio, Luzuriaga, Katherine
Published in The Journal of immunology (1950) (01.05.2017)
Published in The Journal of immunology (1950) (01.05.2017)
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Development of a high-throughput [beta]-Gal-based neutralization assay for quantitation of herpes simplex virus-neutralizing antibodies in human samples
Baccari, Amy, Cooney, Michael, Blevins, Tamara P, Morrison, Lynda A, Larson, Shane, Skoberne, Mojca, Belshe, Robert B, Flechtner, Jessica B, Long, Deborah
Published in Vaccine (19.07.2016)
Published in Vaccine (19.07.2016)
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