The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron
Ichikawa, Saki, Flaxman, Hope A., Xu, Wenqing, Vallavoju, Nandini, Lloyd, Hannah C., Wang, Binyou, Shen, Dacheng, Pratt, Matthew R., Woo, Christina M.
Published in Nature (London) (27.10.2022)
Published in Nature (London) (27.10.2022)
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Journal Article
Development of Photolenalidomide for Cellular Target Identification
Lin, Zhi, Amako, Yuka, Kabir, Farah, Flaxman, Hope A, Budnik, Bogdan, Woo, Christina M
Published in Journal of the American Chemical Society (12.01.2022)
Published in Journal of the American Chemical Society (12.01.2022)
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Journal Article
A Binding Site Hotspot Map of the FKBP12–Rapamycin–FRB Ternary Complex by Photoaffinity Labeling and Mass Spectrometry-Based Proteomics
Flaxman, Hope A, Chang, Chia-Fu, Wu, Hung-Yi, Nakamoto, Carter H, Woo, Christina M
Published in Journal of the American Chemical Society (31.07.2019)
Published in Journal of the American Chemical Society (31.07.2019)
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Journal Article
Enantioselective Synthesis and Biological Evaluation of Sanglifehrin A and B and Analogs
Chang, Chia‐Fu, Flaxman, Hope A., Woo, Christina M.
Published in Angewandte Chemie International Edition (26.07.2021)
Published in Angewandte Chemie International Edition (26.07.2021)
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Journal Article
The cyclimids: Degron-inspired cereblon binders for targeted protein degradation
Ichikawa, Saki, Payne, N. Connor, Xu, Wenqing, Chang, Chia-Fu, Vallavoju, Nandini, Frome, Spencer, Flaxman, Hope A., Mazitschek, Ralph, Woo, Christina M.
Published in Cell chemical biology (20.06.2024)
Published in Cell chemical biology (20.06.2024)
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Journal Article
Biochemical and Functional Evaluation of the Intramolecular Disulfide Bonds in the Zinc-Chelating Antimicrobial Protein Human S100A7 (Psoriasin)
Cunden, Lisa S, Brophy, Megan Brunjes, Rodriguez, Grayson E, Flaxman, Hope A, Nolan, Elizabeth M
Published in Biochemistry (Easton) (31.10.2017)
Published in Biochemistry (Easton) (31.10.2017)
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Journal Article
Sanglifehrin A mitigates multiorgan fibrosis by targeting the collagen chaperone cyclophilin B
Flaxman, Hope A., Chrysovergi, Maria-Anna, Han, Hongwei, Kabir, Farah, Lister, Rachael T., Chang, Chia-Fu, Yvon, Robert, Black, Katharine E., Weigert, Andreas, Savai, Rajkumar, Egea-Zorrilla, Alejandro, Pardo-Saganta, Ana, Lagares, David, Woo, Christina M.
Published in JCI insight (08.08.2024)
Published in JCI insight (08.08.2024)
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Journal Article
Sanglifehrin A mitigates multi-organ fibrosis in vivo by inducing secretion of the collagen chaperone cyclophilin B
Flaxman, Hope A, Chrysovergi, Maria-Anna, Han, Hongwei, Kabir, Farah, Lister, Rachael T, Chang, Chia-Fu, Black, Katharine E, Lagares, David, Woo, Christina M
Published in bioRxiv (09.03.2023)
Published in bioRxiv (09.03.2023)
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Journal Article
Sanglifehrin A mitigates multi-organ fibrosis by targeting the collagen chaperone cyclophilin B
Flaxman, Hope A, Chrysovergi, Maria-Anna, Han, Hongwei, Kabir, Farah, Lister, Rachael T, Chang, Chia-Fu, Yvon, Robert, Black, Katharine E, Weigert, Andreas, Savai, Rajkumar, Egea-Zorrilla, Alejandro, Pardo-Saganta, Ana, Lagares, David, Woo, Christina M
Published in JCI insight (20.06.2024)
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Published in JCI insight (20.06.2024)
Journal Article