Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation
Johansson, Bente Berg, Fjeld, Karianne, Solheim, Marie Holm, Shirakawa, Jun, Zhang, Enming, Keindl, Magdalena, Hu, Jiang, Lindqvist, Andreas, Døskeland, Anne, Mellgren, Gunnar, Flatmark, Torgeir, Njølstad, Pål Rasmus, Kulkarni, Rohit N., Wierup, Nils, Aukrust, Ingvild, Bjørkhaug, Lise
Published in Molecular and cellular endocrinology (15.10.2017)
Published in Molecular and cellular endocrinology (15.10.2017)
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Phenylketonuria as a protein misfolding disease: The mutation pG46S in phenylalanine hydroxylase promotes self-association and fibril formation
Leandro, João, Simonsen, Nina, Saraste, Jaakko, Leandro, Paula, Flatmark, Torgeir
Published in Biochimica et biophysica acta (01.01.2011)
Published in Biochimica et biophysica acta (01.01.2011)
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Allosteric Activation of Human Glucokinase by Free Polyubiquitin Chains and Its Ubiquitin-dependent Cotranslational Proteasomal Degradation
Bjørkhaug, Lise, Molnes, Janne, Søvik, Oddmund, Njølstad, Paål Rasmus, Flatmark, Torgeir
Published in The Journal of biological chemistry (03.08.2007)
Published in The Journal of biological chemistry (03.08.2007)
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Structure of Tetrameric Human Phenylalanine Hydroxylase and Its Implications for Phenylketonuria
Fusetti, F, Erlandsen, H, Flatmark, T, Stevens, R C
Published in The Journal of biological chemistry (03.07.1998)
Published in The Journal of biological chemistry (03.07.1998)
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Journal Article
Diabetes and Pancreatic Exocrine Dysfunction Due to Mutations in the Carboxyl Ester Lipase Gene-Maturity Onset Diabetes of the Young (CEL-MODY)
Johansson, Bente B., Torsvik, Janniche, Bjørkhaug, Lise, Vesterhus, Mette, Ragvin, Anja, Tjora, Erling, Fjeld, Karianne, Hoem, Dag, Johansson, Stefan, Ræder, Helge, Lindquist, Susanne, Hernell, Olle, Cnop, Miriam, Saraste, Jaakko, Flatmark, Torgeir, Molven, Anders, Njølstad, Pål R.
Published in The Journal of biological chemistry (01.10.2011)
Published in The Journal of biological chemistry (01.10.2011)
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Journal Article
Crystal Structure and Site-Specific Mutagenesis of Pterin-Bound Human Phenylalanine Hydroxylase
Erlandsen, Heidi, Bjørgo, Elisa, Flatmark, Torgeir, Stevens, Raymond C
Published in Biochemistry (Easton) (07.03.2000)
Published in Biochemistry (Easton) (07.03.2000)
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Probing the Role of Crystallographically Defined/Predicted Hinge-bending Regions in the Substrate-induced Global Conformational Transition and Catalytic Activation of Human Phenylalanine Hydroxylase by Single-site Mutagenesis
Stokka, Anne Jorunn, Carvalho, Raquel Negrão, Barroso, João Filipe, Flatmark, Torgeir
Published in The Journal of biological chemistry (18.06.2004)
Published in The Journal of biological chemistry (18.06.2004)
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The Effect of Substrate, Dihydrobiopterin, and Dopamine on the EPR Spectroscopic Properties and the Midpoint Potential of the Catalytic Iron in Recombinant Human Phenylalanine Hydroxylase
Hagedoorn, Peter-L., Schmidt, Peter P., Andersson, K. Kristoffer, Hagen, Wilfred R., Flatmark, Torgeir, Martı́nez, Aurora
Published in The Journal of biological chemistry (22.06.2001)
Published in The Journal of biological chemistry (22.06.2001)
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Deamidations in Recombinant Human Phenylalanine Hydroxylase
Carvalho, Raquel Negrão, Solstad, Therese, Bjørgo, Elisa, Barroso, João Filipe, Flatmark, Torgeir
Published in The Journal of biological chemistry (25.04.2003)
Published in The Journal of biological chemistry (25.04.2003)
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Phosphorylation and Mutations of Ser16 in Human Phenylalanine Hydroxylase
Miranda, Frederico Faria, Teigen, Knut, Thórólfsson, Matthı́as, Svebak, Randi M., Knappskog, Per M., Flatmark, Torgeir, Martı́nez, Aurora
Published in The Journal of biological chemistry (25.10.2002)
Published in The Journal of biological chemistry (25.10.2002)
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Journal Article
Diabetes and pancreatic exocrine dysfunction due to mutations in the carboxyl ester lipase gene-maturity onset diabetes of the young (CEL-MODY): a protein misfolding disease
Johansson, Bente B, Torsvik, Janniche, Bjørkhaug, Lise, Vesterhus, Mette, Ragvin, Anja, Tjora, Erling, Fjeld, Karianne, Hoem, Dag, Johansson, Stefan, Ræder, Helge, Lindquist, Susanne, Hernell, Olle, Cnop, Miriam, Saraste, Jaakko, Flatmark, Torgeir, Molven, Anders, Njølstad, Pål R
Published in The Journal of biological chemistry (07.10.2011)
Published in The Journal of biological chemistry (07.10.2011)
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