A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase
Edwards, Marcus J., Flatman, Ruth H., Mitchenall, Lesley A., Stevenson, Clare E. M., Le, Tung B. K., Clarke, Thomas A., McKay, Adam R., Fiedler, Hans-Peter, Buttner, Mark J., Lawson, David M., Maxwell, Anthony
Published in Science (American Association for the Advancement of Science) (04.12.2009)
Published in Science (American Association for the Advancement of Science) (04.12.2009)
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Simocyclinone D8, an Inhibitor of DNA Gyrase with a Novel Mode of Action
FLATMAN, Ruth H, HOWELLS, Alison J, HEIDE, Lutz, FIEDLER, Hans-Peter, MAXWELL, Anthony
Published in Antimicrobial Agents and Chemotherapy (01.03.2005)
Published in Antimicrobial Agents and Chemotherapy (01.03.2005)
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Structure-Activity Relationships of Aminocoumarin-Type Gyrase and Topoisomerase IV Inhibitors Obtained by Combinatorial Biosynthesis
FLATMAN, Ruth H, EUSTAQUIO, Alessandra, LI, Shu-Ming, HEIDE, Lutz, MAXWELL, Anthony
Published in Antimicrobial Agents and Chemotherapy (01.04.2006)
Published in Antimicrobial Agents and Chemotherapy (01.04.2006)
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Journal Article
Emergence of a subfamily of xylanase inhibitors within glycoside hydrolase family 18
Durand, Anne, Hughes, Richard, Roussel, Alain, Flatman, Ruth, Henrissat, Bernard, Juge, Nathalie
Published in The FEBS journal (01.04.2005)
Published in The FEBS journal (01.04.2005)
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Interactions defining the specificity between fungal xylanases and the xylanase-inhibiting protein XIP-I from wheat
Flatman, Ruth, McLauchlan, W Russell, Juge, Nathalie, Furniss, Caroline, Berrin, Jean-Guy, Hughes, Richard K, Manzanares, Paloma, Ladbury, John E, O'Brien, Ronan, Williamson, Gary
Published in Biochemical journal (01.08.2002)
Published in Biochemical journal (01.08.2002)
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Crystallization and preliminary X-ray analysis of a complex formed between the antibiotic simocyclinone D8 and the DNA breakage-reunion domain of Escherichia coli DNA gyrase
Edwards, Marcus J., Flatman, Ruth H., Mitchenall, Lesley A., Stevenson, Clare E. M., Maxwell, Anthony, Lawson, David M.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.08.2009)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.08.2009)
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Specific Characterization of Substrate and Inhibitor Binding Sites of a Glycosyl Hydrolase Family 11 Xylanase fromAspergillus niger
Tahir, Tariq A., Berrin, Jean-Guy, Flatman, Ruth, Roussel, Alain, Roepstorff, Peter, Williamson, Gary, Juge, Nathalie
Published in The Journal of biological chemistry (01.11.2002)
Published in The Journal of biological chemistry (01.11.2002)
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Structural analysis of xylanase inhibitor protein I (XIP-I), a proteinaceous xylanase inhibitor from wheat (Triticum aestivum, var. Soisson)
Payan, Françoise, Flatman, Ruth, Porciero, Sophie, Williamson, Gary, Juge, Nathalie, Roussel, Alain
Published in Biochemical journal (01.06.2003)
Published in Biochemical journal (01.06.2003)
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Journal Article
Specific characterization of substrate and inhibitor binding sites of a glycosyl hydrolase family 11 xylanase from Aspergillus niger
Tahir, Tariq A, Berrin, Jean-Guy, Flatman, Ruth, Roussel, Alain, Roepstorff, Peter, Williamson, Gary, Juge, Nathalie
Published in The Journal of biological chemistry (15.11.2002)
Published in The Journal of biological chemistry (15.11.2002)
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