Application of tail vein serial microsampling for plasma or dried plasma spots in toxicokinetic assessment in rats using acetaminophen as the model compound
Li, Wenkui, Dugyala, Ravi, Devine, Patrick J., Jardel, Matthew, Doherty, John, Kubek, Katie, Lapadula, Daniel, Flarakos, Jimmy
Published in Biomedical chromatography (01.10.2020)
Published in Biomedical chromatography (01.10.2020)
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Journal Article
High-Throughput Solution-Based Medicinal Library Screening against Human Serum Albumin
Flarakos, Jimmy, Morand, Kenneth L, Vouros, Paul
Published in Analytical chemistry (Washington) (01.03.2005)
Published in Analytical chemistry (Washington) (01.03.2005)
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Journal Article
Highly selective and sensitive LC-MS/MS quantification of a therapeutic protein in human serum using immunoaffinity capture enrichment
Fu, Yunlin, Li, Wenkui, Flarakos, Jimmy
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.11.2018)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.11.2018)
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Journal Article
LC–MS/MS determination of a human mAb drug candidate in rat serum using an isotopically labeled universal mAb internal standard
Li, Wenkui, Lin, Hui, Fu, Yunlin, Flarakos, Jimmy
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2017)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.02.2017)
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Journal Article
Dixon’s Q-test and Student’s t-test to assess analog internal standard response in nonregulated LC–MS/MS bioanalysis
Barkley, Deborah, Hatsis, Panos, Glick, Jim, Li, Wenkui, Flarakos, Jimmy
Published in Bioanalysis (01.11.2020)
Published in Bioanalysis (01.11.2020)
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Journal Article
Quantitative analysis of pasireotide (SOM230), a cyclic peptide, in monkey plasma using liquid chromatography in combination with tandem mass spectrometry
Fu, Yunlin, Li, Wenkui, Flarakos, Jimmy, Tse, Francis L.S.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.01.2016)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.01.2016)
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Journal Article
Differential Mobility Spectrometry Coupled with Multiple Ion Monitoring in Regulated LC-MS/MS Bioanalysis of a Therapeutic Cyclic Peptide in Human Plasma
Fu, Yunlin, Xia, Yuan-Qing, Flarakos, Jimmy, Tse, Francis L.S, Miller, Jeffrey D, Jones, Elliott B, Li, Wenkui
Published in Analytical chemistry (Washington) (05.04.2016)
Published in Analytical chemistry (Washington) (05.04.2016)
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Journal Article
Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline
Flarakos, Jimmy, Du, Yancy, Gu, Helen, Wang, Lai, Einolf, Heidi J., Chun, Dung Y., Zhu, Bing, Alexander, Natalia, Natrillo, Adrienne, Hanna, Imad, Ting, Lillian, Zhou, Wei, Dole, Kiran, Sun, Haiying, Kovacs, Steven J., Stein, Daniel S., Tanaka, S. Ken, Villano, Stephen, Mangold, James B.
Published in Xenobiotica (03.08.2017)
Published in Xenobiotica (03.08.2017)
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Journal Article
Disposition and metabolism of [14C] Sacubitril/Valsartan (formerly LCZ696) an angiotensin receptor neprilysin inhibitor, in healthy subjects
Flarakos, Jimmy, Du, Yancy, Bedman, Timothy, Al-Share, Qusai, Jordaan, Pierre, Chandra, Priya, Albrecht, Diego, Wang, Lai, Gu, Helen, Einolf, Heidi J., Huskey, Su-Er, Mangold, James B.
Published in Xenobiotica (01.11.2016)
Published in Xenobiotica (01.11.2016)
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Journal Article
Development and validation of an LC–MS/MS method for the quantitative analysis of the adenosine A2a receptor antagonist NIR178 and its monohydroxy metabolite in human plasma: Application to clinical pharmacokinetics
Heudi, Olivier, Plaud, Nathalie, Aumonier, Celine, Wu, Shari, Hatsis, Panos, Hurtado, Felipe K., Picard, Franck, Winter, Serge, Flarakos, Jimmy
Published in Biomedical chromatography (01.10.2020)
Published in Biomedical chromatography (01.10.2020)
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Journal Article
Pharmacokinetics, Distribution, Metabolism, and Excretion of Omadacycline following a Single Intravenous or Oral Dose of 14C-Omadacycline in Rats
Lin, Wen, Flarakos, Jimmy, Du, Yancy, Hu, Wenyu, He, Handan, Mangold, James, Tanaka, S Ken, Villano, Stephen
Published in Antimicrobial agents and chemotherapy (01.01.2017)
Published in Antimicrobial agents and chemotherapy (01.01.2017)
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Journal Article
Pharmacokinetics, Distribution, Metabolism, and Excretion of Omadacycline following a Single Intravenous or Oral Dose of 14 C-Omadacycline in Rats
Lin, Wen, Flarakos, Jimmy, Du, Yancy, Hu, Wenyu, He, Handan, Mangold, James, Tanaka, S. Ken, Villano, Stephen
Published in Antimicrobial agents and chemotherapy (01.01.2017)
Published in Antimicrobial agents and chemotherapy (01.01.2017)
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Journal Article