Cryo-EM structures of tau filaments from Alzheimer’s disease
Fitzpatrick, Anthony W. P., Falcon, Benjamin, He, Shaoda, Murzin, Alexey G., Murshudov, Garib, Garringer, Holly J., Crowther, R. Anthony, Ghetti, Bernardino, Goedert, Michel, Scheres, Sjors H. W.
Published in Nature (London) (13.07.2017)
Published in Nature (London) (13.07.2017)
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Journal Article
Role of Intermolecular Forces in Defining Material Properties of Protein Nanofibrils
Knowles, Tuomas P, Fitzpatrick, Anthony W, Meehan, Sarah, Mott, Helen R, Vendruscolo, Michele, Dobson, Christopher M, Welland, Mark E
Published in Science (American Association for the Advancement of Science) (21.12.2007)
Published in Science (American Association for the Advancement of Science) (21.12.2007)
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Journal Article
Metastability of Native Proteins and the Phenomenon of Amyloid Formation
Baldwin, Andrew J, Knowles, Tuomas P. J, Tartaglia, Gian Gaetano, Fitzpatrick, Anthony W, Devlin, Glyn L, Shammas, Sarah Lucy, Waudby, Christopher A, Mossuto, Maria F, Meehan, Sarah, Gras, Sally L, Christodoulou, John, Anthony-Cahill, Spencer J, Barker, Paul D, Vendruscolo, Michele, Dobson, Christopher M
Published in Journal of the American Chemical Society (14.09.2011)
Published in Journal of the American Chemical Society (14.09.2011)
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Journal Article
Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu
Ho, Chi-Min, Li, Xiaorun, Lai, Mason, Terwilliger, Thomas C., Beck, Josh R., Wohlschlegel, James, Goldberg, Daniel E., Fitzpatrick, Anthony W. P., Zhou, Z. Hong
Published in Nature methods (01.01.2020)
Published in Nature methods (01.01.2020)
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Journal Article
Atomic structure and hierarchical assembly of a cross-β amyloid fibril
Fitzpatrick, Anthony W. P., Debelouchina, Galia T., Bayro, Marvin J., Clare, Daniel K., Caporini, Marc A., Bajaj, Vikram S., Jaroniec, Christopher P., Wang, Luchun, Ladizhansky, Vladimir, Müller, Shirley A., MacPhee, Cait E., Waudby, Christopher A., Mott, Helen R., De Simone, Alfonso, Knowles, Tuomas P. J., Saibil, Helen R., Vendruscolo, Michele, Orlova, Elena V., Griffin, Robert G., Dobson, Christopher M.
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (02.04.2013)
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Journal Article
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
Fitzpatrick, Anthony W, Knowles, Tuomas P J, Waudby, Christopher A, Vendruscolo, Michele, Dobson, Christopher M
Published in PLoS computational biology (01.10.2011)
Published in PLoS computational biology (01.10.2011)
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Journal Article
4D Cryo-Electron Microscopy of Proteins
Fitzpatrick, Anthony W. P, Lorenz, Ulrich J, Vanacore, Giovanni M, Zewail, Ahmed H
Published in Journal of the American Chemical Society (26.12.2013)
Published in Journal of the American Chemical Society (26.12.2013)
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Journal Article
In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-synuclein within E. coli cells
Waudby, Christopher A, Camilloni, Carlo, Fitzpatrick, Anthony W P, Cabrita, Lisa D, Dobson, Christopher M, Vendruscolo, Michele, Christodoulou, John
Published in PloS one (26.08.2013)
Published in PloS one (26.08.2013)
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Journal Article
Structure of the MacAB–TolC ABC-type tripartite multidrug efflux pump
Fitzpatrick, Anthony W. P., Llabrés, Salomé, Neuberger, Arthur, Blaza, James N., Bai, Xiao-Chen, Okada, Ui, Murakami, Satoshi, van Veen, Hendrik W., Zachariae, Ulrich, Scheres, Sjors H. W., Luisi, Ben F., Du, Dijun
Published in Nature microbiology (15.05.2017)
Published in Nature microbiology (15.05.2017)
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Journal Article
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Kumar, Mukesh, Duong, Duc M., Wesseling, Hendrik, Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Petrucelli, Leonard, Steen, Judith A., Fitzpatrick, Anthony W.P.
Published in Cell (20.02.2020)
Published in Cell (20.02.2020)
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Journal Article
Cryo-EM of amyloid fibrils and cellular aggregates
Fitzpatrick, Anthony WP, Saibil, Helen R
Published in Current opinion in structural biology (01.10.2019)
Published in Current opinion in structural biology (01.10.2019)
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Journal Article
Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases
Chang, Andrew, Xiang, Xinyu, Wang, Jing, Lee, Carolyn, Arakhamia, Tamta, Simjanoska, Marija, Wang, Chi, Carlomagno, Yari, Zhang, Guoan, Dhingra, Shikhar, Thierry, Manon, Perneel, Jolien, Heeman, Bavo, Forgrave, Lauren M., DeTure, Michael, DeMarco, Mari L., Cook, Casey N., Rademakers, Rosa, Dickson, Dennis W., Petrucelli, Leonard, Stowell, Michael H.B., Mackenzie, Ian R.A., Fitzpatrick, Anthony W.P.
Published in Cell (14.04.2022)
Published in Cell (14.04.2022)
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Journal Article
Structures of LRP2 reveal a molecular machine for endocytosis
Beenken, Andrew, Cerutti, Gabriele, Brasch, Julia, Guo, Yicheng, Sheng, Zizhang, Erdjument-Bromage, Hediye, Aziz, Zainab, Robbins-Juarez, Shelief Y., Chavez, Estefania Y., Ahlsen, Goran, Katsamba, Phinikoula S., Neubert, Thomas A., Fitzpatrick, Anthony W.P., Barasch, Jonathan, Shapiro, Lawrence
Published in Cell (16.02.2023)
Published in Cell (16.02.2023)
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Journal Article
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Kumar, Mukesh, Duong, Duc M., Wesseling, Hendrik, Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Petrucelli, Leonard, Steen, Judith A., Fitzpatrick, Anthony W.P.
Published in Cell (09.12.2021)
Published in Cell (09.12.2021)
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Journal Article
The AD tau core spontaneously self-assembles and recruits full-length tau to filaments
Carlomagno, Yari, Manne, Sireesha, DeTure, Michael, Prudencio, Mercedes, Zhang, Yong-Jie, Hanna Al-Shaikh, Rana, Dunmore, Judith A., Daughrity, Lillian M., Song, Yuping, Castanedes-Casey, Monica, Lewis-Tuffin, Laura J., Nicholson, Katharine A., Wszolek, Zbigniew K., Dickson, Dennis W., Fitzpatrick, Anthony W.P., Petrucelli, Leonard, Cook, Casey N.
Published in Cell reports (Cambridge) (16.03.2021)
Published in Cell reports (Cambridge) (16.03.2021)
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Journal Article
Higher Order Amyloid Fibril Structure by MAS NMR and DNP Spectroscopy
Debelouchina, Galia T, Bayro, Marvin J, Fitzpatrick, Anthony W, Ladizhansky, Vladimir, Colvin, Michael T, Caporini, Marc A, Jaroniec, Christopher P, Bajaj, Vikram S, Rosay, Melanie, MacPhee, Cait E, Vendruscolo, Michele, Maas, Werner E, Dobson, Christopher M, Griffin, Robert G
Published in Journal of the American Chemical Society (26.12.2013)
Published in Journal of the American Chemical Society (26.12.2013)
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