The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
Boyle, D L, Soma, K, Hodge, J, Kavanaugh, A, Mandel, D, Mease, P, Shurmur, R, Singhal, A K, Wei, N, Rosengren, S, Kaplan, I, Krishnaswami, S, Luo, Z, Bradley, J, Firestein, G S
Published in Annals of the rheumatic diseases (01.06.2015)
Published in Annals of the rheumatic diseases (01.06.2015)
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Journal Article
Choline kinase inhibition in rheumatoid arthritis
Guma, M, Sanchez-Lopez, E, Lodi, A, Garcia-Carbonell, R, Tiziani, S, Karin, M, Lacal, J C, Firestein, G S
Published in Annals of the rheumatic diseases (01.07.2015)
Published in Annals of the rheumatic diseases (01.07.2015)
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Journal Article
Assessment of rituximab’s immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results
Kavanaugh, A, Rosengren, S, Lee, S J, Hammaker, D, Firestein, G S, Kalunian, K, Wei, N, Boyle, D L
Published in Annals of the rheumatic diseases (01.03.2008)
Published in Annals of the rheumatic diseases (01.03.2008)
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Journal Article
Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study
Buch, M H, Boyle, D L, Rosengren, S, Saleem, B, Reece, R J, Rhodes, L A, Radjenovic, A, English, A, Tang, H, Vratsanos, G, O’Connor, P, Firestein, G S, Emery, P
Published in Annals of the rheumatic diseases (01.07.2009)
Published in Annals of the rheumatic diseases (01.07.2009)
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Journal Article
Mitogen activated protein kinase inhibitors: where are we now and where are we going?
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Journal Article
Conference Proceeding
Signal transduction networks in rheumatoid arthritis
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Journal Article
Conference Proceeding
Cellular electrophysiological principles that modulate secretion from synovial fibroblasts
Clark, R. B., Schmidt, T. A., Sachse, F. B., Boyle, D., Firestein, G. S., Giles, W. R.
Published in The Journal of physiology (01.02.2017)
Published in The Journal of physiology (01.02.2017)
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Journal Article
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
Han, Z, Boyle, D L, Chang, L, Bennett, B, Karin, M, Yang, L, Manning, A M, Firestein, G S
Published in The Journal of clinical investigation (01.07.2001)
Published in The Journal of clinical investigation (01.07.2001)
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Journal Article
Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy
Adriaansen, J, Tas, S W, Klarenbeek, P L, Bakker, A C, Apparailly, F, Firestein, G S, Jorgensen, C, Vervoordeldonk, M J B M, Tak, P P
Published in Annals of the rheumatic diseases (01.12.2005)
Published in Annals of the rheumatic diseases (01.12.2005)
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Journal Article
Validated gene expression biomarker analysis for biopsy‐based clinical trials in ulcerative colitis
Boland, B. S., Boyle, D. L., Sandborn, W. J., Firestein, G. S., Levesque, B. G., Hillman, J., Zhang, B., Proudfoot, J., Eckmann, L., Ernst, P. B., Rivera‐Nieves, J., Pola, S., Copur‐Dahi, N., Chang, J. T.
Published in Alimentary pharmacology & therapeutics (01.09.2014)
Published in Alimentary pharmacology & therapeutics (01.09.2014)
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Journal Article
Synergistic benefit in inflammatory arthritis by targeting IκB kinase ϵ and interferon β
Corr, M, Boyle, D L, Ronacher, L, Flores, N, Firestein, G S
Published in Annals of the rheumatic diseases (01.02.2009)
Published in Annals of the rheumatic diseases (01.02.2009)
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Journal Article
MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice
Sorkin, L.S, Boyle, D.L, Hammaker, D, Herman, D.S, Vail, E, Firestein, G.S
Published in Neuroscience (18.08.2009)
Published in Neuroscience (18.08.2009)
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Journal Article
NF-kappa B regulation by I kappa B kinase-2 in rheumatoid arthritis synoviocytes
Aupperle, K, Bennett, B, Han, Z, Boyle, D, Manning, A, Firestein, G
Published in The Journal of immunology (1950) (15.02.2001)
Published in The Journal of immunology (1950) (15.02.2001)
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Journal Article
HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation
Cramer, Thorsten, Yamanishi, Yuji, Clausen, Björn E., Förster, Irmgard, Pawlinski, Rafal, Mackman, Nigel, Haase, Volker H., Jaenisch, Rudolf, Corr, Maripat, Nizet, Victor, Firestein, Gary S., Gerber, Hans-Peter, Ferrara, Napoleone, Johnson, Randall S.
Published in Cell (07.03.2003)
Published in Cell (07.03.2003)
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Journal Article