Validation of the BOADICEA model in a prospective cohort of BRCA1/2 pathogenic variant carriers
Yang, Xin, Mooij, Thea M, Leslie, Goska, Ficorella, Lorenzo, Andrieu, Nadine, Kast, Karin, Singer, Christian F., Jakubowska, Anna, van Gils, Carla H, Tan, Yen Y, Engel, Christoph, Adank, Muriel A, van Asperen, Christi J, Ausems, Margreet G E M, Berthet, Pascaline, Collee, Margriet J, Cook, Jackie A, Eason, Jacqueline, Spaendonck-Zwarts, Karin Y van, Evans, D. Gareth, Gómez García, Encarna B, Hanson, Helen, Izatt, Louise, Kemp, Zoe, Lalloo, Fiona, Lasset, Christine, Lesueur, Fabienne, Musgrave, Hannah, Nambot, Sophie, Noguès, Catherine, Oosterwijk, Jan C, Stoppa-lyonnet, Dominique, Tischkowitz, Marc, Tripathi, Vishakha, Wevers, Marijke R, Zhao, Emily, van Leeuwen, Flora E, Schmidt, Marjanka K, Easton, Douglas F, Rookus, Matti A, Antoniou, Antonis C, Kanani, Farah, Davidson, Rosemarie, Snape, Katie, Side, Lucy, Copeland, Harriet, Ahmed, Munaza, Brennan, Paul, Walker, Lisa, Murray, Jennie, Donaldson, Alan, Searle, Claire, Morrison, Patrick, Barwell, Julian, Rogers, Mark T, New, Rachel Hart, Brady, Angela, Gallagher, David, Miedzybrodzka, Zosia, Conti, Hector, Murray, Alex, Ong, Kai-Ren, Kennedy, John, Gregory, Helen
Published in Journal of medical genetics (01.08.2024)
Published in Journal of medical genetics (01.08.2024)
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Extent of investigation and management of cases of ‘unexplained’ mismatch repair deficiency (u-dMMR): a UK Cancer Genetics Group consensus
McVeigh, Terri Patricia, Monahan, Kevin J, Christopher, Joseph, West, Nick, Scott, Malcolm, Murray, Jennie, Hanson, Helen, Armstrong, Ruth, Beggs, Andrew, Berlin, Cheryl, Boyde, Adam, Brady, Angela, Bulmer, Jeremy, Burghel, George, Burn, John, Catherwood, Mark, Christopher, Joseph, Cleaver, Ruth, Coad, Beth, Conti, Hector, Cook, Jacqueline, Cope, Wei, Corbett, Gemma, Crosbie, Emma, Davidson, Rosemarie, DeSouza, Bianca, Donaldson, Alan, Durkie, Miranda, Eccles, Diana, Foot, Nicola, Frayling, Ian, George, Andrew, Gerrard, Gareth, Gibson, Sarah, Green, Andrew, Greville-Heygate, Stephanie, Hamilton, Sarah, Hanson, Helen, Hart, Rachel, Hodgson, Shirley, Holliday, Debbie, Hoyle, Jacqui, Jewell, Rosalyn, Kemp, Zoe, Kiely, Louise, Kiesel, Vicki, Kohut, Kelly, Kristeleit, Rebecca, Kumar, Ajith, Lalloo, Fiona, Latchford, Andrew, Lee, Natalie, Lobo, Donna, Loughrey, Maurice, MacMahon, Suzanne, Martin, Richard, Martin, Sally, McVeigh, Terri, Miedzybrodzka, Zosia, Minshall, Eleanor, Monahan, Kevin, Monje-Garcia, Laura, Morgan, Meleri, Mugalaasi, Hood, Murray, Jennie, Musgrave, Hannah, Nastali, Emily, Norbury, Gail, Ong, Kai Ren, Onyeador, Nicola, Pagan, Judith, Quigley, Kezia, Ratsma, Elizabeth, Rea, Gillian, Repana, Dimitra, Rosenthal, Adam, Scott, Malcolm, Searle, Claire, Shaw, Adam, Side, Lucy, Simon, Kate, Smith, Katherine, Solomons, Joyce, Varde, Avani, West, Nick, Wiggins, Jennifer, Wren, Dorte, Yarram-Smith, Laura
Published in Journal of medical genetics (01.07.2024)
Published in Journal of medical genetics (01.07.2024)
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Germline mismatch repair (MMR) gene analyses from English NHS regional molecular genomics laboratories 1996-2020: development of a national resource of patient-level genomics laboratory records
Loong, Lucy, Huntley, Catherine, McRonald, Fiona, Santaniello, Francesco, Pethick, Joanna, Torr, Bethany, Allen, Sophie, Tulloch, Oliver, Goel, Shilpi, Shand, Brian, Rahman, Tameera, Luchtenborg, Margreet, Garrett, Alice, Barber, Richard, Bedenham, Tina, Bourn, David, Bradshaw, Kirsty, Brooks, Claire, Bruty, Jonathan, Burghel, George J, Butler, Samantha, Buxton, Chris, Callaway, Alison, Callaway, Jonathan, Drummond, James, Durkie, Miranda, Field, Joanne, Jenkins, Lucy, McVeigh, Terri P, Mountford, Roger, Nyanhete, Rodney, Petrides, Evgenia, Robinson, Rachel, Scott, Tracy, Stinton, Victoria, Tellez, James, Wallace, Andrew J, Yarram-Smith, Laura, Sahan, Kate, Hallowell, Nina, Eccles, Diana M, Pharoah, Paul, Tischkowitz, Marc, Antoniou, Antonis C, Evans, D Gareth, Lalloo, Fiona, Norbury, Gail, Morris, Eva, Burn, John, Hardy, Steven, Turnbull, Clare
Published in Journal of medical genetics (01.07.2023)
Published in Journal of medical genetics (01.07.2023)
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Sensitivity of BRCA1/2 testing in high-risk breast/ovarian/male breast cancer families: little contribution of comprehensive RNA/NGS panel testing
Byers, Helen, Wallis, Yvonne, van Veen, Elke M, Lalloo, Fiona, Reay, Kim, Smith, Philip, Wallace, Andrew J, Bowers, Naomi, Newman, William G, Evans, D Gareth
Published in European journal of human genetics : EJHG (01.11.2016)
Published in European journal of human genetics : EJHG (01.11.2016)
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SDHC phaeochromocytoma and paraganglioma: A UK‐wide case series
Williams, Sophie T., Chatzikyriakou, Prodromos, Carroll, Paul V., McGowan, Barbara M., Velusamy, Anand, White, Gemma, Obholzer, Rupert, Akker, Scott, Tufton, Nicola, Casey, Ruth T., Maher, Eamonn R., Park, Soo‐Mi, Porteous, Mary, Dyer, Rebecca, Tan, Tricia, Wernig, Florian, Brady, Angela F., Kosicka‐Slawinska, Monika, Whitelaw, Benjamin C., Dorkins, Huw, Lalloo, Fiona, Brennan, Paul, Carlow, Joseph, Martin, Richard, Mitchell, Anna L., Harrison, Rachel, Hawkes, Lara, Newell‐Price, John, Kelsall, Alan, Igbokwe, Rebecca, Adlard, Julian, Schirwani, Schaida, Davidson, Rosemarie, Morrison, Patrick J., Chung, Teng‐Teng, Bowles, Christopher, Izatt, Louise
Published in Clinical endocrinology (Oxford) (01.04.2022)
Published in Clinical endocrinology (Oxford) (01.04.2022)
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Hereditary Leiomyomatosis and Renal Cell Cancer: Clinical, Molecular, and Screening Features in a Cohort of 185 Affected Individuals
Forde, Claire, Lim, Derek H.K., Alwan, Yousef, Burghel, George, Butland, Laura, Cleaver, Ruth, Dixit, Abhijit, Evans, D. Gareth, Hanson, Helen, Lalloo, Fiona, Oliveira, Pedro, Vialard, Lindsey, Wallis, Yvonne, Maher, Eamonn R., Woodward, Emma R.
Published in European urology oncology (01.12.2020)
Published in European urology oncology (01.12.2020)
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Surgical outcome measures (SOMs) in a cohort of patients at high risk of breast cancer treated by bilateral risk reducing mastectomy (BRRM) and breast reconstruction
Duxbury, Paula, Lalloo, Fiona, Dave, Rajiv, Wisely, Julie, Evans, Gareth, Howell, Tony, Gandhi, Ashu
Published in European journal of surgical oncology (01.05.2017)
Published in European journal of surgical oncology (01.05.2017)
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Associations of height, body mass index, and weight gain with breast cancer risk in carriers of a pathogenic variant in BRCA1 or BRCA2: the BRCA1 and BRCA2 Cohort Consortium
Kast, Karin, John, Esther M, Hopper, John L, Andrieu, Nadine, Noguès, Catherine, Mouret-Fourme, Emmanuelle, Lasset, Christine, Fricker, Jean-Pierre, Berthet, Pascaline, Mari, Véronique, Salle, Lucie, Schmidt, Marjanka K, Ausems, Margreet G E M, Garcia, Encarnacion B Gomez, van de Beek, Irma, Wevers, Marijke R, Evans, D Gareth, Tischkowitz, Marc, Lalloo, Fiona, Cook, Jackie, Izatt, Louise, Tripathi, Vishakha, Snape, Katie, Musgrave, Hannah, Sharif, Saba, Murray, Jennie, Colonna, Sarah V, Andrulis, Irene L, Daly, Mary B, Southey, Melissa C, de la Hoya, Miguel, Osorio, Ana, Foretova, Lenka, Berkova, Dita, Gerdes, Anne-Marie, Olah, Edith, Jakubowska, Anna, Singer, Christian F, Tan, Yen, Augustinsson, Annelie, Rantala, Johanna, Simard, Jacques, Schmutzler, Rita K, Milne, Roger L, Phillips, Kelly-Anne, Terry, Mary Beth, Goldgar, David, van Leeuwen, Flora E, Mooij, Thea M, Antoniou, Antonis C, Easton, Douglas F, Rookus, Matti A, Engel, Christoph
Published in Breast cancer research : BCR (20.06.2023)
Published in Breast cancer research : BCR (20.06.2023)
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Risk of Contralateral Breast Cancer in Women with and without Pathogenic Variants in BRCA1, BRCA2 , and TP53 Genes in Women with Very Early-Onset (<36 Years) Breast Cancer
Hyder, Zerin, Harkness, Elaine F, Woodward, Emma R, Bowers, Naomi L, Pereira, Marta, Wallace, Andrew J, Howell, Sacha J, Howell, Anthony, Lalloo, Fiona, Newman, William G, Smith, Miriam J, Evans, D Gareth
Published in Cancers (07.02.2020)
Published in Cancers (07.02.2020)
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Journal Article
Risk of breast cancer in male BRCA2 carriers
Evans, D G R, Susnerwala, I, Dawson, J, Woodward, E, Maher, E R, Lalloo, F
Published in Journal of medical genetics (01.10.2010)
Published in Journal of medical genetics (01.10.2010)
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Penetrance estimates for BRCA1, BRCA2 (also applied to Lynch syndrome) based on presymptomatic testing: a new unbiased method to assess risk?
Evans, D Gareth, Woodward, Emma, Harkness, Elaine F, Howell, Anthony, Plaskocinska, Inga, Maher, Eamonn R, Tischkowitz, Marc D, Lalloo, Fiona
Published in Journal of medical genetics (01.07.2018)
Published in Journal of medical genetics (01.07.2018)
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Journal Article
Long-Term Evaluation of Women Referred to a Breast Cancer Family History Clinic (Manchester UK 1987-2020)
Howell, Anthony, Gandhi, Ashu, Howell, Sacha, Wilson, Mary, Maxwell, Anthony, Astley, Susan, Harvie, Michelle, Pegington, Mary, Barr, Lester, Baildam, Andrew, Harkness, Elaine, Hopwood, Penelope, Wisely, Julie, Wilding, Andrea, Greenhalgh, Rosemary, Affen, Jenny, Maurice, Andrew, Cole, Sally, Wiseman, Julia, Lalloo, Fiona, French, David P, Evans, D Gareth
Published in Cancers (09.12.2020)
Published in Cancers (09.12.2020)
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Journal Article
Gene Panel Testing for Breast Cancer Reveals Differential Effect of Prior BRCA1/2 Probability
Evans, D. Gareth, van Veen, Elke M., Woodward, Emma R., Harkness, Elaine F., Ellingford, Jamie M., Bowers, Naomi L., Wallace, Andrew J., Howell, Sacha J., Howell, Anthony, Lalloo, Fiona, Newman, William G., Smith, Miriam J.
Published in Cancers (18.08.2021)
Published in Cancers (18.08.2021)
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Urgent improvements needed to diagnose and manage Lynch syndrome
Monahan, Kevin J, Alsina, Deborah, Bach, Simon, Buchanan, James, Burn, John, Clark, Sue, Dawson, Peter, De Souza, Bianca, Din, Farhat V N, Dolwani, Sunil, Dunlop, Malcolm G, East, James, Evans, D Gareth, Fearnhead, Nicola, Frayling, Ian M, Glynne-Jones, Rob, Hill, James, Houlston, Richard, Hull, Mark, Lalloo, Fiona, Latchford, Andrew, Lishman, Suzy, Quirke, Phil, Rees, Colin, Rutter, Matt, Sasieni, Peter, Senapati, Asha, Speake, Doug, Thomas, Huw, Tomlinson, Ian
Published in BMJ (Online) (20.03.2017)
Published in BMJ (Online) (20.03.2017)
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Is Reflex Germline IBRCA1/2/I Testing Necessary in Women Diagnosed with Non-Mucinous High-Grade Epithelial Ovarian Cancer Aged 80 Years or Older?
Morgan, Robert D, Burghel, George J, Flaum, Nicola, Bulman, Michael, Smith, Philip, Clamp, Andrew R, Hasan, Jurjees, Mitchell, Claire L, Salih, Zena, Woodward, Emma R, Lalloo, Fiona, Crosbie, Emma J, Edmondson, Richard J, Schlecht, Helene, Jayson, Gordon C, Evans, D. Gareth R
Published in Cancers (01.01.2023)
Published in Cancers (01.01.2023)
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Journal Article
Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study
Girardi, Fabio, Barnes, Daniel R., Barrowdale, Daniel, Frost, Debra, Brady, Angela F., Miller, Claire, Henderson, Alex, Donaldson, Alan, Murray, Alex, Brewer, Carole, Pottinger, Caroline, Evans, D Gareth, Eccles, Diana, Lalloo, Fiona, Gregory, Helen, Cook, Jackie, Eason, Jacqueline, Adlard, Julian, Barwell, Julian, Ong, Kai Ren, Walker, Lisa, Izatt, Louise, Side, Lucy E., Kennedy, M John, Tischkowitz, Marc, Rogers, Mark T., Porteous, Mary E., Morrison, Patrick J., Eeles, Ros, Davidson, Rosemarie, Snape, Katie, Easton, Douglas F., Antoniou, Antonis C
Published in Genetics in medicine (01.12.2018)
Published in Genetics in medicine (01.12.2018)
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Evaluation of SDHB, SDHD and VHL gene susceptibility testing in the assessment of individuals with non-syndromic phaeochromocytoma, paraganglioma and head and neck paraganglioma
Jafri, Mariam, Whitworth, James, Rattenberry, Eleanor, Vialard, Lindsey, Kilby, Gail, Kumar, Ajith V., Izatt, Louise, Lalloo, Fiona, Brennan, Paul, Cook, Jackie, Morrison, Patrick J., Canham, Natalie, Armstrong, Ruth, Brewer, Carole, Tomkins, Susan, Donaldson, Alan, Barwell, Julian, Cole, Trevor R., Atkinson, A. Brew, Aylwin, Simon, Ball, Steve G., Srirangalingam, Umasuthan, Chew, Shern L., Evans, Dafydd Gareth R, Hodgson, Shirley V., Irving, Richard, Woodward, Emma, Macdonald, Fiona, Maher, Eamonn R.
Published in Clinical endocrinology (Oxford) (01.06.2013)
Published in Clinical endocrinology (Oxford) (01.06.2013)
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CNVs affecting cancer predisposing genes (CPGs) detected as incidental findings in routine germline diagnostic chromosomal microarray (CMA) testing
Innes, Josie, Reali, Lisa, Clayton-Smith, Jill, Hall, Georgina, Lim, Derek HK, Burghel, George J, French, Kim, Khan, Unzela, Walker, Daniel, Lalloo, Fiona, Evans, D Gareth R, McMullan, Dominic, Maher, Eamonn R, Woodward, Emma R
Published in Journal of medical genetics (01.02.2018)
Published in Journal of medical genetics (01.02.2018)
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Journal Article
Is Reflex Germline BRCA1/2 Testing Necessary in Women Diagnosed with Non-Mucinous High-Grade Epithelial Ovarian Cancer Aged 80 Years or Older?
Morgan, Robert D, Burghel, George J, Flaum, Nicola, Bulman, Michael, Smith, Philip, Clamp, Andrew R, Hasan, Jurjees, Mitchell, Claire L, Salih, Zena, Woodward, Emma R, Lalloo, Fiona, Crosbie, Emma J, Edmondson, Richard J, Schlecht, Helene, Jayson, Gordon C, Evans, D Gareth R
Published in Cancers (25.01.2023)
Published in Cancers (25.01.2023)
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