Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies
Zhou, Xiaolai, Nicholson, Alexandra M, Ren, Yingxue, Brooks, Mieu, Jiang, Peizhou, Zuberi, Aamir, Phuoc, Hung Nguyen, Perkerson, Ralph B, Matchett, Billie, Parsons, Tammee M, Finch, NiCole A, Lin, Wenlang, Qiao, Wenhui, Castanedes-Casey, Monica, Phillips, Virginia, Librero, Ariston L, Asmann, Yan, Bu, Guojun, Murray, Melissa E, Lutz, Cathleen, Dickson, Dennis W, Rademakers, Rosa
Published in Brain (London, England : 1878) (01.06.2020)
Published in Brain (London, England : 1878) (01.06.2020)
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Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy
Kouri, Naomi, Ross, Owen A., Dombroski, Beth, Younkin, Curtis S., Serie, Daniel J., Soto-Ortolaza, Alexandra, Baker, Matthew, Finch, Ni Cole A., Yoon, Hyejin, Kim, Jungsu, Fujioka, Shinsuke, McLean, Catriona A., Ghetti, Bernardino, Spina, Salvatore, Cantwell, Laura B., Farlow, Martin R., Grafman, Jordan, Huey, Edward D., Ryung Han, Mi, Beecher, Sherry, Geller, Evan T., Kretzschmar, Hans A., Roeber, Sigrun, Gearing, Marla, Juncos, Jorge L., Vonsattel, Jean Paul G., Van Deerlin, Vivianna M., Grossman, Murray, Hurtig, Howard I., Gross, Rachel G., Arnold, Steven E., Trojanowski, John Q., Lee, Virginia M., Wenning, Gregor K., White, Charles L., Höglinger, Günter U., Müller, Ulrich, Devlin, Bernie, Golbe, Lawrence I., Crook, Julia, Parisi, Joseph E., Boeve, Bradley F., Josephs, Keith A., Wszolek, Zbigniew K., Uitti, Ryan J., Graff-Radford, Neill R., Litvan, Irene, Younkin, Steven G., Wang, Li-San, Ertekin-Taner, Nilüfer, Rademakers, Rosa, Hakonarsen, Hakon, Schellenberg, Gerard D., Dickson, Dennis W.
Published in Nature communications (16.06.2015)
Published in Nature communications (16.06.2015)
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Journal Article
CSF1R mutations link POLD and HDLS as a single disease entity
Nicholson, Alexandra M, Baker, Matt C, Finch, Nicole A, Rutherford, Nicola J, Wider, Christian, Graff-Radford, Neill R, Nelson, Peter T, Clark, H Brent, Wszolek, Zbigniew K, Dickson, Dennis W, Knopman, David S, Rademakers, Rosa
Published in Neurology (12.03.2013)
Published in Neurology (12.03.2013)
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Novel clinical associations with specific C9ORF72 transcripts in patients with repeat expansions in C9ORF72
van Blitterswijk, Marka, Gendron, Tania F., Baker, Matthew C., DeJesus-Hernandez, Mariely, Finch, NiCole A., Brown, Patricia H., Daughrity, Lillian M., Murray, Melissa E., Heckman, Michael G., Jiang, Jie, Lagier-Tourenne, Clotilde, Edbauer, Dieter, Cleveland, Don W., Josephs, Keith A., Parisi, Joseph E., Knopman, David S., Petersen, Ronald C., Petrucelli, Leonard, Boeve, Bradley F., Graff-Radford, Neill R., Boylan, Kevin B., Dickson, Dennis W., Rademakers, Rosa
Published in Acta neuropathologica (01.12.2015)
Published in Acta neuropathologica (01.12.2015)
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Journal Article
Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study
van Blitterswijk, Marka, PhD, DeJesus-Hernandez, Mariely, BS, Niemantsverdriet, Ellis, BS, Murray, Melissa E, PhD, Heckman, Michael G, MS, Diehl, Nancy N, BS, Brown, Patricia H, MS, Baker, Matthew C, BSc, Finch, NiCole A, MS, Bauer, Peter O, PhD, Serrano, Geidy, PhD, Beach, Thomas G, Prof, Josephs, Keith A, Prof, Knopman, David S, Prof, Petersen, Ronald C, Prof, Boeve, Bradley F, Prof, Graff-Radford, Neill R, Prof, Boylan, Kevin B, MD, Petrucelli, Leonard, Prof, Dickson, Dennis W, Prof, Rademakers, Rosa, Dr
Published in Lancet neurology (01.10.2013)
Published in Lancet neurology (01.10.2013)
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Journal Article
TYROBP genetic variants in early-onset Alzheimer's disease
Pottier, Cyril, Ravenscroft, Thomas A, Brown, Patricia H, Finch, NiCole A, Baker, Matt, Parsons, Meeia, Asmann, Yan W, Ren, Yingxue, Christopher, Elizabeth, Levitch, Denise, van Blitterswijk, Marka, Cruchaga, Carlos, Campion, Dominique, Nicolas, Gaël, Richard, Anne-Claire, Guerreiro, Rita, Bras, Jose T, Zuchner, Stephan, Gonzalez, Michael A, Bu, Guojun, Younkin, Steven, Knopman, David S, Josephs, Keith A, Parisi, Joseph E, Petersen, Ronald C, Ertekin-Taner, Nilüfer, Graff-Radford, Neill R, Boeve, Bradley F, Dickson, Dennis W, Rademakers, Rosa
Published in Neurobiology of aging (01.12.2016)
Published in Neurobiology of aging (01.12.2016)
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Journal Article
Progranulin protein levels are differently regulated in plasma and CSF
Nicholson, Alexandra M, Finch, NiCole A, Thomas, Colleen S, Wojtas, Aleksandra, Rutherford, Nicola J, Mielke, Michelle M, Roberts, Rosebud O, Boeve, Bradley F, Knopman, David S, Petersen, Ronald C, Rademakers, Rosa
Published in Neurology (27.05.2014)
Published in Neurology (27.05.2014)
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Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion
Udine, Evan, DeJesus-Hernandez, Mariely, Tian, Shulan, das Neves, Sofia Pereira, Crook, Richard, Finch, NiCole A., Baker, Matthew C., Pottier, Cyril, Graff-Radford, Neill R., Boeve, Bradley F., Petersen, Ronald C., Knopman, David S., Josephs, Keith A., Oskarsson, Björn, Da Mesquita, Sandro, Petrucelli, Leonard, Gendron, Tania F., Dickson, Dennis W., Rademakers, Rosa, van Blitterswijk, Marka
Published in Acta neuropathologica (01.06.2024)
Published in Acta neuropathologica (01.06.2024)
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Journal Article
Prosaposin is a regulator of progranulin levels and oligomerization
Nicholson, Alexandra M., Finch, NiCole A., Almeida, Marcio, Perkerson, Ralph B., van Blitterswijk, Marka, Wojtas, Aleksandra, Cenik, Basar, Rotondo, Sergio, Inskeep, Venette, Almasy, Laura, Dyer, Thomas, Peralta, Juan, Jun, Goo, Wood, Andrew R., Frayling, Timothy M., Fuchsberger, Christian, Fowler, Sharon, Teslovich, Tanya M., Manning, Alisa K., Kumar, Satish, Curran, Joanne, Lehman, Donna, Abecasis, Goncalo, Duggirala, Ravindranath, Pottier, Cyril, Zahir, Haaris A., Crook, Julia E., Karydas, Anna, Mitic, Laura, Sun, Ying, Dickson, Dennis W., Bu, Guojun, Herz, Joachim, Yu, Gang, Miller, Bruce L., Ferguson, Shawn, Petersen, Ronald C., Graff-Radford, Neill, Blangero, John, Rademakers, Rosa
Published in Nature communications (30.06.2016)
Published in Nature communications (30.06.2016)
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Journal Article
A Point Mutation in PDGFRB Causes Autosomal-Dominant Penttinen Syndrome
Johnston, Jennifer J., Sanchez-Contreras, Monica Y., Keppler-Noreuil, Kim M., Sapp, Julie, Crenshaw, Molly, Finch, NiCole A., Cormier-Daire, Valerie, Rademakers, Rosa, Sybert, Virginia P., Biesecker, Leslie G.
Published in American journal of human genetics (03.09.2015)
Published in American journal of human genetics (03.09.2015)
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Journal Article
In-depth clinico-pathological examination of RNA foci in a large cohort of C9ORF72 expansion carriers
DeJesus-Hernandez, Mariely, Finch, NiCole A., Wang, Xue, Gendron, Tania F., Bieniek, Kevin F., Heckman, Michael G., Vasilevich, Aliaksei, Murray, Melissa E., Rousseau, Linda, Weesner, Rachael, Lucido, Anthony, Parsons, Meeia, Chew, Jeannie, Josephs, Keith A., Parisi, Joseph E., Knopman, David S., Petersen, Ronald C., Boeve, Bradley F., Graff-Radford, Neill R., de Boer, Jan, Asmann, Yan W., Petrucelli, Leonard, Boylan, Kevin B., Dickson, Dennis W., van Blitterswijk, Marka, Rademakers, Rosa
Published in Acta neuropathologica (01.08.2017)
Published in Acta neuropathologica (01.08.2017)
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Journal Article
Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers
Jackson, Jazmyne L, Finch, NiCole A, Baker, Matthew C, Kachergus, Jennifer M, DeJesus-Hernandez, Mariely, Pereira, Kimberly, Christopher, Elizabeth, Prudencio, Mercedes, Heckman, Michael G, Thompson, E Aubrey, Dickson, Dennis W, Shah, Jaimin, Oskarsson, Björn, Petrucelli, Leonard, Rademakers, Rosa, van Blitterswijk, Marka
Published in Molecular neurodegeneration (30.01.2020)
Published in Molecular neurodegeneration (30.01.2020)
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Journal Article
Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers
Dickson, Dennis W, Baker, Matthew C, Jackson, Jazmyne L, DeJesus-Hernandez, Mariely, Finch, NiCole A, Tian, Shulan, Heckman, Michael G, Pottier, Cyril, Gendron, Tania F, Murray, Melissa E, Ren, Yingxue, Reddy, Joseph S, Graff-Radford, Neill R, Boeve, Bradley F, Petersen, Ronald C, Knopman, David S, Josephs, Keith A, Petrucelli, Leonard, Oskarsson, Björn, Sheppard, John W, Asmann, Yan W, Rademakers, Rosa, van Blitterswijk, Marka
Published in Acta neuropathologica communications (08.10.2019)
Published in Acta neuropathologica communications (08.10.2019)
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Journal Article
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity
Nicholson, Alexandra M, Zhou, Xiaolai, Perkerson, Ralph B, Parsons, Tammee M, Chew, Jeannie, Brooks, Mieu, DeJesus-Hernandez, Mariely, Finch, NiCole A, Matchett, Billie J, Kurti, Aishe, Jansen-West, Karen R, Perkerson, Emilie, Daughrity, Lillian, Castanedes-Casey, Monica, Rousseau, Linda, Phillips, Virginia, Hu, Fenghua, Gendron, Tania F, Murray, Melissa E, Dickson, Dennis W, Fryer, John D, Petrucelli, Leonard, Rademakers, Rosa
Published in Acta neuropathologica communications (31.05.2018)
Published in Acta neuropathologica communications (31.05.2018)
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