Antitumor activity of poly(ethylene glycol)–camptothecin conjugate: The inhibition of tumor growth in vivo
Yu, Deshan, Peng, Ping, Dharap, Sonia S., Wang, Yang, Mehlig, Mary, Chandna, Pooja, Zhao, Hong, Filpula, David, Yang, Karen, Borowski, Virna, Borchard, Gerrit, Zhang, Zhihua, Minko, Tamara
Published in Journal of controlled release (10.12.2005)
Published in Journal of controlled release (10.12.2005)
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Linear and Branched Bicin Linkers for Releasable PEGylation of Macromolecules: Controlled Release in Vivo and in Vitro from Mono- and Multi-PEGylated Proteins
Zhao, Hong, Yang, Karen, Martinez, Anthony, Basu, Amartya, Chintala, Ramesh, Liu, Hsien-Ching, Janjua, Ahsen, Wang, Maoliang, Filpula, David
Published in Bioconjugate chemistry (01.03.2006)
Published in Bioconjugate chemistry (01.03.2006)
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A Novel, Highly Stable Fold of the Immunoglobulin Binding Domain of Streptococcal Protein G
Gronenborn, Angela M., Filpula, David R., Essig, Nina Z., Achari, Aniruddha, Whitlow, Marc, Wingfield, Paul T., Clore, G. Marius
Published in Science (American Association for the Advancement of Science) (09.08.1991)
Published in Science (American Association for the Advancement of Science) (09.08.1991)
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Journal Article
A RNA antagonist of hypoxia-inducible factor-1α, EZN-2968, inhibits tumor cell growth
Greenberger, Lee M., Horak, Ivan D., Filpula, David, Sapra, Puja, Westergaard, Majken, Frydenlund, Henrik F., Albæk, Charlotte, Schrøder, Henrik, Ørum, Henrik
Published in Molecular cancer therapeutics (01.11.2008)
Published in Molecular cancer therapeutics (01.11.2008)
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Journal Article
Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation
Basu, Amartya, Yang, Karen, Wang, Maoliang, Liu, Sam, Chintala, Ramesh, Palm, Thomas, Zhao, Hong, Peng, Ping, Wu, Dechun, Zhang, Zhenfan, Hua, Jack, Hsieh, Ming-Ching, Zhou, John, Petti, Gerald, Li, Xiguang, Janjua, Ahsen, Mendez, Magda, Liu, Jun, Longley, Clifford, Zhang, Zhihua, Mehlig, Mary, Borowski, Virna, Viswanathan, Manickam, Filpula, David
Published in Bioconjugate chemistry (01.05.2006)
Published in Bioconjugate chemistry (01.05.2006)
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Journal Article
Structural and Functional Repetition in a Marine Mussel Adhesive Protein
Filpula, David R., Lee, Shwu-Maan, Link, Rebecca P., Strausberg, Susan L., Strausberg, Robert L.
Published in Biotechnology Progress. 1990 (01.05.1990)
Published in Biotechnology Progress. 1990 (01.05.1990)
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Conference Proceeding
Abstract 602: Silencing of the androgen receptor (AR) with a novel mRNA antisense oligonucleotide causes antitumor effects in xenograft models of prostate cancer
Zhang, Yixian, Castaneda, Stephen, Kim, Steven, Kraft, Patricia, Bandaru, Raj, Filpula, David, Greenberger, Lee M., Horak, Ivan D.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Abstract 600: Targeting the hedgehog pathway by LNA (locked nucleic acid) oligonucleotide-based GLI2 RNA antagonists, EZN-4482 and EZN-4496, in vitro and in vivo
Qu, Zhengxing, Zhang, Yixian, Shi, Victoria, Zhu, Peifang, Kim, Steven, Castaneda, Stephen, Wang, Maoliang, Filpula, David, Greenberger, Lee M., Horak, Ivan D.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Abstract 601: In vitro and in vivo inhibition of β-catenin by two novel β-catenin RNA antagonists, EZN-3889 and 3892
Zhang, Yixian, Kim, Steven, Shi, Victoria, Qu, Zhengxing, Castaneda, Stephen, Wang, Maoliang, Zhu, Peifang, Filpula, David, Greenberger, Lee M., Horak, Ivan D.
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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Journal Article
Prolonged Circulating Lives of Single-Chain Fv Proteins Conjugated with Polyethylene Glycol: A Comparison of Conjugation Chemistries and Compounds
Lee, L. Stanford, Conover, Charles, Shi, Celine, Whitlow, Marc, Filpula, David
Published in Bioconjugate chemistry (01.11.1999)
Published in Bioconjugate chemistry (01.11.1999)
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Journal Article
Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation
Yang, Karen, Basu, Amartya, Wang, Maoliang, Chintala, Ramesh, Hsieh, Ming-Ching, Liu, Sam, Hua, Jack, Zhang, Zhenfan, Zhou, John, Li, Mark, Phyu, Hnin, Petti, Gerald, Mendez, Magda, Janjua, Haleema, Peng, Ping, Longley, Clifford, Borowski, Virna, Mehlig, Mary, Filpula, David
Published in Protein engineering (01.10.2003)
Published in Protein engineering (01.10.2003)
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Journal Article
Releasable PEGylation of Mesothelin Targeted Immunotoxin SS1P Achieves Single Dosage Complete Regression of a Human Carcinoma in Mice
Filpula, David, Yang, Karen, Basu, Amartya, Hassan, Raffit, Xiang, Laiman, Zhang, Zhenfan, Wang, Maoliang, Wang, Qing-cheng, Ho, Mitchell, Beers, Richard, Zhao, Hong, Peng, Ping, Zhou, John, Li, Xiguang, Petti, Gerald, Janjua, Ahsen, Liu, Jun, Wu, Dechun, Yu, Deshan, Zhang, Zhihua, Longley, Clifford, FitzGerald, David, Kreitman, Robert J, Pastan, Ira
Published in Bioconjugate chemistry (01.05.2007)
Published in Bioconjugate chemistry (01.05.2007)
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Journal Article
Abstract C146: LNA (locked nucleic acid) oligonucleotide based GLI2 RNA antagonist EZN-4482 effectively inhibited tumor growth and increased survival of animals with liver metastasis
Zhang, Yixian, Sapra, Puja, Kim, Steven, Zhu, Peifang, Qu, Zhengxing, Castaneda, Stephen, Wang, Maoliang, Filpula, David, Greenberger, Lee M., Horak, Ivan D.
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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