Mitochondrial DNA copy number in human disease: the more the better?
Filograna, Roberta, Mennuni, Mara, Alsina, David, Larsson, Nils‐Göran
Published in FEBS letters (01.04.2021)
Published in FEBS letters (01.04.2021)
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Journal Article
Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View
Filograna, Roberta, Beltramini, Mariano, Bubacco, Luigi, Bisaglia, Marco
Published in Current neuropharmacology (01.04.2016)
Published in Current neuropharmacology (01.04.2016)
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Journal Article
Analysis of the Catecholaminergic Phenotype in Human SH-SY5Y and BE(2)-M17 Neuroblastoma Cell Lines upon Differentiation
Filograna, Roberta, Civiero, Laura, Ferrari, Vanni, Codolo, Gaia, Greggio, Elisa, Bubacco, Luigi, Beltramini, Mariano, Bisaglia, Marco
Published in PloS one (28.08.2015)
Published in PloS one (28.08.2015)
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Journal Article
Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo
Pajak, Aleksandra, Laine, Isabelle, Clemente, Paula, El-Fissi, Najla, Schober, Florian A, Maffezzini, Camilla, Calvo-Garrido, Javier, Wibom, Rolf, Filograna, Roberta, Dhir, Ashish, Wedell, Anna, Freyer, Christoph, Wredenberg, Anna
Published in PLoS genetics (01.07.2019)
Published in PLoS genetics (01.07.2019)
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Journal Article
The Clinical use of the Neutrophil to Lymphocyte Ratio (NLR) in Urothelial Cancer: a systematic review
Marchioni, Michele, Primiceri, Giulia, Ingrosso, Manuela, Filograna, Roberta, Castellan, Pietro, De Francresco, Piergustavo, Schips, Luigi
Published in Clinical genitourinary cancer (01.12.2016)
Published in Clinical genitourinary cancer (01.12.2016)
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Journal Article
A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease
Kauppila, Johanna H.K., Baines, Holly L., Bratic, Ana, Simard, Marie-Lune, Freyer, Christoph, Mourier, Arnaud, Stamp, Craig, Filograna, Roberta, Larsson, Nils-Göran, Greaves, Laura C., Stewart, James B.
Published in Cell reports (Cambridge) (13.09.2016)
Published in Cell reports (Cambridge) (13.09.2016)
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Journal Article
A role for BCL2L13 and autophagy in germline purifying selection of mtDNA
Kremer, Laura S, Bozhilova, Lyuba V, Rubalcava-Gracia, Diana, Filograna, Roberta, Upadhyay, Mamta, Koolmeister, Camilla, Chinnery, Patrick F, Larsson, Nils-Göran
Published in PLoS genetics (06.01.2023)
Published in PLoS genetics (06.01.2023)
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Journal Article
Mitochondrial dysfunction in adult midbrain dopamine neurons triggers an early immune response
Filograna, Roberta, Lee, Seungmin, Tiklová, Katarína, Mennuni, Mara, Jonsson, Viktor, Ringnér, Markus, Gillberg, Linda, Sopova, Elena, Shupliakov, Oleg, Koolmeister, Camilla, Olson, Lars, Perlmann, Thomas, Larsson, Nils-Göran
Published in PLoS genetics (27.09.2021)
Published in PLoS genetics (27.09.2021)
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Journal Article
PARKIN is not required to sustain OXPHOS function in adult mammalian tissues
Filograna, Roberta, Gerlach, Jule, Choi, Hae-Na, Rigoni, Giovanni, Barbaro, Michela, Oscarson, Mikael, Lee, Seungmin, Tiklova, Katarina, Ringnér, Markus, Koolmeister, Camilla, Wibom, Rolf, Riggare, Sara, Nennesmo, Inger, Perlmann, Thomas, Wredenberg, Anna, Wedell, Anna, Motori, Elisa, Svenningsson, Per, Larsson, Nils-Göran
Published in NPJ Parkinson's Disease (29.04.2024)
Published in NPJ Parkinson's Disease (29.04.2024)
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Journal Article
Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations
Zhang, Jingdian, Koolmeister, Camilla, Han, Jinming, Filograna, Roberta, Hanke, Leo, Àdori, Monika, Sheward, Daniel J., Teifel, Sina, Gopalakrishna, Shreekara, Shao, Qiuya, Liu, Yong, Zhu, Keying, Harris, Robert A., McInerney, Gerald, Murrell, Ben, Aoun, Mike, Bäckdahl, Liselotte, Holmdahl, Rikard, Pekalski, Marcin, Wedell, Anna, Engvall, Martin, Wredenberg, Anna, Hedestam, Gunilla B. Karlsson, Dopico, Xaquin Castro, Rorbach, Joanna
Published in JCI insight (08.09.2023)
Published in JCI insight (08.09.2023)
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Journal Article
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells
Russo, Isabella, Berti, Giulia, Plotegher, Nicoletta, Bernardo, Greta, Filograna, Roberta, Bubacco, Luigi, Greggio, Elisa
Published in Journal of neuroinflammation (09.12.2015)
Published in Journal of neuroinflammation (09.12.2015)
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Journal Article
3001 MtDNA copy number correlates to coronary artery calcium score and biological age in kidney failure patients
Schwarz, Angelina, Qureshi, Abdul Rashid Tony, Filograna, Roberta, Wennberg, Lars, Wernerson, Annika, Witasp, Anna, Stenvinkel, Peter
Published in Nephrology, dialysis, transplantation (23.05.2024)
Published in Nephrology, dialysis, transplantation (23.05.2024)
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Journal Article
Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE
Filograna, Roberta, Godena, Vinay K, Sanchez-Martinez, Alvaro, Ferrari, Emanuele, Casella, Luigi, Beltramini, Mariano, Bubacco, Luigi, Whitworth, Alexander J, Bisaglia, Marco
Published in The Journal of biological chemistry (22.04.2016)
Published in The Journal of biological chemistry (22.04.2016)
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Journal Article
Maintained respiratory chain capacity in mice with severely reduced levels of mitochondrial respirasomes
Misic, Jelena, Milenkovic, Dusanka, Hevler, Johannes F., Molinié, Thibaut, Chung, Injae, Atanassov, Ilian, Li, Xinping, Filograna, Roberta, Mesaros, Andrea, Mourier, Arnaud, Heck, Albert J.R., Hirst, Judy, Larsson, Nils-Göran
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2024)
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2024)
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Journal Article
Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR‐Cas9 screen
Mennuni, Mara, Filograna, Roberta, Felser, Andrea, Bonekamp, Nina A, Giavalisco, Patrick, Lytovchenko, Oleksandr, Larsson, Nils‐Göran
Published in EMBO reports (05.01.2022)
Published in EMBO reports (05.01.2022)
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Journal Article
Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes
Milenkovic, Dusanka, Misic, Jelena, Hevler, Johannes F., Molinié, Thibaut, Chung, Injae, Atanassov, Ilian, Li, Xinping, Filograna, Roberta, Mesaros, Andrea, Mourier, Arnaud, Heck, Albert J.R., Hirst, Judy, Larsson, Nils-Göran
Published in Cell metabolism (03.10.2023)
Published in Cell metabolism (03.10.2023)
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Journal Article
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss
Biosa, Alice, Sanchez-Martinez, Alvaro, Filograna, Roberta, Terriente-Felix, Ana, Alam, Sarah M, Beltramini, Mariano, Bubacco, Luigi, Bisaglia, Marco, Whitworth, Alexander J
Published in Human molecular genetics (01.05.2018)
Published in Human molecular genetics (01.05.2018)
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Journal Article
Mammalian RNase H1 directs RNA primer formation for mtDNA replication initiation and is also necessary for mtDNA replication completion
Misic, Jelena, Milenkovic, Dusanka, Al-Behadili, Ali, Xie, Xie, Jiang, Min, Jiang, Shan, Filograna, Roberta, Koolmeister, Camilla, Siira, Stefan J, Jenninger, Louise, Filipovska, Aleksandra, Clausen, Anders R, Caporali, Leonardo, Valentino, Maria Lucia, La Morgia, Chiara, Carelli, Valerio, Nicholls, Thomas J, Wredenberg, Anna, Falkenberg, Maria, Larsson, Nils-Göran
Published in Nucleic acids research (26.08.2022)
Published in Nucleic acids research (26.08.2022)
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Journal Article