Pancreatic cancer models for translational research
Behrens, Diana, Walther, Wolfgang, Fichtner, Iduna
Published in Pharmacology & therapeutics (Oxford) (01.05.2017)
Published in Pharmacology & therapeutics (Oxford) (01.05.2017)
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Journal Article
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
Stein, Ulrike, Walther, Wolfgang, Arlt, Franziska, Schwabe, Holger, Smith, Janice, Fichtner, Iduna, Birchmeier, Walter, Schlag, Peter M
Published in Nature medicine (01.01.2009)
Published in Nature medicine (01.01.2009)
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Journal Article
Establishment of Patient-Derived Non–Small Cell Lung Cancer Xenografts as Models for the Identification of Predictive Biomarkers
FICHTNER, Iduna, ROLFF, Jana, SOONG, Richie, HOFFMANN, Jens, HAMMER, Stefanie, SOMMER, Anette, BECKER, Michael, MERK, Johannes
Published in Clinical cancer research (15.10.2008)
Published in Clinical cancer research (15.10.2008)
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Journal Article
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine
Rivera, Maria, Fichtner, Iduna, Wulf-Goldenberg, Annika, Sers, Christine, Merk, Johannes, Patone, Giannino, Alp, Keziban M., Kanashova, Tamara, Mertins, Philipp, Hoffmann, Jens, Stein, Ulrike, Walther, Wolfgang
Published in Neoplasia (New York, N.Y.) (01.01.2021)
Published in Neoplasia (New York, N.Y.) (01.01.2021)
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Journal Article
The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells
Redmer, Torben, Welte, Yvonne, Behrens, Diana, Fichtner, Iduna, Przybilla, Dorothea, Wruck, Wasco, Yaspo, Marie-Laure, Lehrach, Hans, Schäfer, Reinhold, Regenbrecht, Christian R A
Published in PloS one (05.05.2014)
Published in PloS one (05.05.2014)
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Journal Article
Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP
Piggott, Luke, Silva, Andreia, Robinson, Timothy, Santiago-Gómez, Angelica, Simões, Bruno M, Becker, Michael, Fichtner, Iduna, Andera, Ladislav, Young, Philippa, Morris, Christine, Barrett-Lee, Peter, Alchami, Fouad, Piva, Marco, Vivanco, Maria dM, Clarke, Robert B, Gee, Julia, Clarkson, Richard
Published in Clinical cancer research (15.05.2018)
Published in Clinical cancer research (15.05.2018)
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Journal Article
A comprehensively characterized large panel of head and neck cancer patient‐derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option
Klinghammer, Konrad, Raguse, Jan‐Dirk, Plath, Thomas, Albers, Andreas E., Joehrens, Korinna, Zakarneh, Andre, Brzezicha, Bernadette, Wulf‐Goldenberg, Annika, Keilholz, Ulrich, Hoffmann, Jens, Fichtner, Iduna
Published in International journal of cancer (15.06.2015)
Published in International journal of cancer (15.06.2015)
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Journal Article
Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma
Weilemann, Andre, Grau, Michael, Erdmann, Tabea, Merkel, Olaf, Sobhiafshar, Ulduz, Anagnostopoulos, Ioannis, Hummel, Michael, Siegert, Antje, Hayford, Claudia, Madle, Hannelore, Wollert-Wulf, Brigitte, Fichtner, Iduna, Dörken, Bernd, Dirnhofer, Stephan, Mathas, Stephan, Janz, Martin, Emre, N. C. Tolga, Rosenwald, Andreas, Ott, German, Lenz, Peter, Tzankov, Alexandar, Lenz, Georg
Published in Blood (01.01.2015)
Published in Blood (01.01.2015)
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Journal Article
Loss-of-function uORF mutations in human malignancies
Schulz, Julia, Mah, Nancy, Neuenschwander, Martin, Kischka, Tabea, Ratei, Richard, Schlag, Peter M, Castaños-Vélez, Esmeralda, Fichtner, Iduna, Tunn, Per-Ulf, Denkert, Carsten, Klaas, Oliver, Berdel, Wolfgang E, von Kries, Jens P, Makalowski, Wojciech, Andrade-Navarro, Miguel A, Leutz, Achim, Wethmar, Klaus
Published in Scientific reports (05.02.2018)
Published in Scientific reports (05.02.2018)
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Journal Article
Author Correction: Loss-of-function uORF mutations in human malignancies
Schulz, Julia, Mah, Nancy, Neuenschwander, Martin, Kischka, Tabea, Ratei, Richard, Schlag, Peter M, Castaños-Vélez, Esmeralda, Fichtner, Iduna, Tunn, Per-Ulf, Denkert, Carsten, Klaas, Oliver, Berdel, Wolfgang E, von Kries, Jens P, Makalowski, Wojciech, Andrade-Navarro, Miguel A, Leutz, Achim, Wethmar, Klaus
Published in Scientific reports (28.01.2021)
Published in Scientific reports (28.01.2021)
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Journal Article
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells
Bachmeier, Beatrice, Fichtner, Iduna, Killian, Peter H, Kronski, Emanuel, Pfeffer, Ulrich, Efferth, Thomas
Published in PloS one (26.05.2011)
Published in PloS one (26.05.2011)
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Journal Article
Clinically relevant glioblastoma patient-derived xenograft models to guide drug development and identify molecular signatures
Alcaniz, Joshua, Winkler, Lars, Dahlmann, Mathias, Becker, Michael, Orthmann, Andrea, Haybaeck, Johannes, Krassnig, Stefanie, Skofler, Christina, Kratzsch, Tobias, Kuhn, Susanne A, Jödicke, Andreas, Linnebacher, Michael, Fichtner, Iduna, Walther, Wolfgang, Hoffmann, Jens
Published in Frontiers in oncology (11.04.2023)
Published in Frontiers in oncology (11.04.2023)
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Journal Article
Establishment and Thorough Characterization of Xenograft (PDX) Models Derived from Patients with Pancreatic Cancer for Molecular Analyses and Chemosensitivity Testing
Behrens, Diana, Pfohl, Ulrike, Conrad, Theresia, Becker, Michael, Brzezicha, Bernadette, Büttner, Britta, Wagner, Silvia, Hallas, Cora, Lawlor, Rita, Khazak, Vladimir, Linnebacher, Michael, Wartmann, Thomas, Fichtner, Iduna, Hoffmann, Jens, Dahlmann, Mathias, Walther, Wolfgang
Published in Cancers (01.12.2023)
Published in Cancers (01.12.2023)
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Journal Article
Pharmacologic activity and pharmacokinetics of metabolites of regorafenib in preclinical models
Zopf, Dieter, Fichtner, Iduna, Bhargava, Ajay, Steinke, Wolfram, Thierauch, Karl‐Heinz, Diefenbach, Konstanze, Wilhelm, Scott, Hafner, Frank‐Thorsten, Gerisch, Michael
Published in Cancer medicine (Malden, MA) (01.11.2016)
Published in Cancer medicine (Malden, MA) (01.11.2016)
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Journal Article
Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy
Brueckner, Bodo, Rius, Maria, Markelova, Maria Rivera, Fichtner, Iduna, Hals, Petter-Arnt, Sandvold, Marit Liland, Lyko, Frank
Published in Molecular cancer therapeutics (01.05.2010)
Published in Molecular cancer therapeutics (01.05.2010)
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Journal Article
GIPC1 regulates MACC1-driven metastasis
Siegel, Franziska, Schmidt, Hannes, Juneja, Manisha, Smith, Janice, Herrmann, Pia, Kobelt, Dennis, Sharma, Kamal, Fichtner, Iduna, Walther, Wolfgang, Dittmar, Gunnar, Volkmer, Rudolf, Rathjen, Fritz G, Schlag, Peter M, Stein, Ulrike
Published in Frontiers in oncology (2023)
Published in Frontiers in oncology (2023)
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Journal Article
Intervening in β-Catenin Signaling by Sulindac Inhibits S100A4-Dependent Colon Cancer Metastasis
Stein, Ulrike, Arlt, Franziska, Smith, Janice, Sack, Ulrike, Herrmann, Pia, Walther, Wolfgang, Lemm, Margit, Fichtner, Iduna, Shoemaker, Robert H, Schlag, Peter M
Published in Neoplasia (New York, N.Y.) (01.02.2011)
Published in Neoplasia (New York, N.Y.) (01.02.2011)
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Journal Article
Evaluation of combination therapy schedules of doxorubicin and an acid-sensitive albumin-binding prodrug of doxorubicin in the MIA PaCa-2 pancreatic xenograft model
Kratz, Felix, Azab, Samar, Zeisig, Reiner, Fichtner, Iduna, Warnecke, André
Published in International journal of pharmaceutics (30.01.2013)
Published in International journal of pharmaceutics (30.01.2013)
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Journal Article
Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance
Grasse, Sabrina, Lienhard, Matthias, Frese, Steffen, Kerick, Martin, Steinbach, Anne, Grimm, Christina, Hussong, Michelle, Rolff, Jana, Becker, Michael, Dreher, Felix, Schirmer, Uwe, Boerno, Stefan, Ramisch, Anna, Leschber, Gunda, Timmermann, Bernd, Grohé, Christian, Lüders, Heike, Vingron, Martin, Fichtner, Iduna, Klein, Sebastian, Odenthal, Margarete, Büttner, Reinhard, Lehrach, Hans, Sültmann, Holger, Herwig, Ralf, Schweiger, Michal R
Published in Genome medicine (20.07.2018)
Published in Genome medicine (20.07.2018)
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Journal Article
Cell death sensitization of leukemia cells by opioid receptor activation
Friesen, Claudia, Roscher, Mareike, Hormann, Inis, Fichtner, Iduna, Alt, Andreas, Hilger, Ralf A, Debatin, Klaus-Michael, Miltner, Erich
Published in Oncotarget (01.05.2013)
Published in Oncotarget (01.05.2013)
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