Utilization of a mouse/human chimeric model for long term metabolic testing of human skin
Quantin, P., Ghazi, K., Pereira, U., Smith, A., Degardin, L., Vigneron, P., Ficheux, H., Garlick, J., Rapetti, L., Egles, C.
Published in Journal of pharmacological and toxicological methods (01.03.2020)
Published in Journal of pharmacological and toxicological methods (01.03.2020)
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Perspectives and strategies of alternative methods used in the risk assessment of personal care products
Quantin, P, Thélu, A, Catoire, S, Ficheux, H
Published in Annales pharmaceutiques françaises (01.11.2015)
Published in Annales pharmaceutiques françaises (01.11.2015)
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Rhein, the metabolite of diacerhein, reduces the proliferation of osteoarthritic chondrocytes and synoviocytes without inducing apoptosis
Legendre, F., Heuze, A., Boukerrouche, K., Leclercq, S., Boumediene, K., Galera, P., Domagala, F., Pujol, J. -P., Ficheux, H.
Published in Scandinavian journal of rheumatology (01.01.2009)
Published in Scandinavian journal of rheumatology (01.01.2009)
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Rhein, a diacerhein-derived metabolite, modulates the expression of matrix degrading enzymes and the cell proliferation of articular chondrocytes by inhibiting ERK and JNK-AP-1 dependent pathways
LEGENDRE, F, BOGDANOWICZ, P, MARTIN, G, DOMAGALA, F, LECLERCQ, S, PUJOL, J.-P, FICHEUX, H
Published in Clinical and experimental rheumatology (01.07.2007)
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Published in Clinical and experimental rheumatology (01.07.2007)
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Comparison of the effects of fasting morning, fasting evening and fed bedtime administration of tenatoprazole on intragastric pH in healthy volunteers: a randomized three‐way crossover study
THOMSON, A. B. R., COHEN, P., FICHEUX, H., FIORENTINI, P., DOMAGALA, F., HOMERIN, M., TACCOEN, A.
Published in Alimentary pharmacology & therapeutics (01.04.2006)
Published in Alimentary pharmacology & therapeutics (01.04.2006)
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Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay
Nesslany, Fabrice, Simar-Meintières, Sophie, Ficheux, Hervé, Marzin, Daniel
Published in Mutation research (01.08.2009)
Published in Mutation research (01.08.2009)
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Simultaneous determination of hemoglobin and coproporphyrin by second derivative differential spectrophotometry: application to the diagnosis of meconium aspiration
Ficheux, H., Levillain, P., Francoual, J., Leluc, R., Lemonnier, A.
Published in Clinica chimica acta (15.06.1989)
Published in Clinica chimica acta (15.06.1989)
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Effects of rhein on human articular chondrocytes in alginate beads
Sanchez, Christelle, Mathy-Hartert, Marianne, Deberg, Michelle A, Ficheux, Herve, Reginster, Jean-Yves L, Henrotin, Yves E
Published in Biochemical pharmacology (01.02.2003)
Published in Biochemical pharmacology (01.02.2003)
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Rhein inhibits interleukin-1 beta-induced activation of MEK/ERK pathway and DNA binding of NF-kappa B and AP-1 in chondrocytes cultured in hypoxia: a potential mechanism for its disease-modifying effect in osteoarthritis
Martin, Grégoire, Bogdanowicz, Patrick, Domagala, Florence, Ficheux, Hervé, Pujol, Jean-Pierre
Published in Inflammation (01.08.2003)
Published in Inflammation (01.08.2003)
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Modulatory effect of rhein on IL-1alpha-induced responses in human chondrocytes: a comparative study between antibody microarrays and specific ELISAs
Deffaud, J, Kirchmeyer, M, Domagala, F, Ficheux, H, Netter, P, Bianchi, A, Jouzeau, J-Y
Published in Biorheology (Oxford) (2008)
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Published in Biorheology (Oxford) (2008)
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Inhibition of interleukin-1beta-induced activation of MEK/ERK pathway and DNA binding of NF-kappaB and AP-1: potential mechanism for Diacerein effects in osteoarthritis
Domagala, F, Martin, G, Bogdanowicz, P, Ficheux, H, Pujol, J-P
Published in Biorheology (Oxford) (2006)
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Published in Biorheology (Oxford) (2006)
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Synthesis of quinone and xanthone analogs of rhein
Fonteneau, Nadia, Martin, Philippe, Mondon, Martine, Ficheux, Hervé, Gesson, Jean-Pierre
Published in Tetrahedron (29.10.2001)
Published in Tetrahedron (29.10.2001)
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