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Process for preparing substituted 5-fluoro-1H-pyrazolopyridines

Process for preparing substituted 5-fluoro-1H-pyrazolopyridines

by FEY, PETER, GRUNENBERG, ALFONS, BIERER, DONALD
Year of Publication 01.03.2017

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Patent

Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate active compound product having improved properties, production and formulation thereof

Methyl {4,6-diamino-2-[5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate active compound product having improved properties, production and formulation thereof

by FEY, PETER, NEUMANN, HEIKE, BECKER, GUIDO, SOWA, MICHAL, BROCKOB, JOERG, LONGERICH, MARKUS
Year of Publication 01.11.2020

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Patent

Method for separating methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4- dihydro-5-pyrimidine- carboxylate- racemate

Method for separating methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4- dihydro-5-pyrimidine- carboxylate- racemate

by SIEGFRIED GOLDMANN, PETER FEY
Year of Publication 03.06.2005

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Patent

Proceso para la hidrólisis de ésteres carboxílicos de quinolona

Proceso para la hidrólisis de ésteres carboxílicos de quinolona

by BERWE, Mathias, DIETZEL, Antje, FEY, Peter, LONGERICH, Markus, WISCHNAT, Ralf, WIRTHS, Jörg
Year of Publication 30.10.2020

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Patent

PROCEDIMIENTO DE PREPARACIÓN DE 5-FLUORO-1H-PIRAZOLOPIRIDINAS SUSTITUIDAS

PROCEDIMIENTO DE PREPARACIÓN DE 5-FLUORO-1H-PIRAZOLOPIRIDINAS SUSTITUIDAS

by DONALD BIERER, ALFONS GRUNENBERG, PETER FEY
Year of Publication 15.02.2017

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Patent

Procedimiento para la preparación de (3s)-3-(4-cloro-3-{[(2s,3r)-2-(4-clorofenil)-4,4,4-trifluor-3-metilbutanoil] amino}fenil)-3-ácido ciclopropilpropanoico y su forma cristalina para uso como principio activo farmacéutico

Procedimiento para la preparación de (3s)-3-(4-cloro-3-{[(2s,3r)-2-(4-clorofenil)-4,4,4-trifluor-3-metilbutanoil] amino}fenil)-3-ácido ciclopropilpropanoico y su forma cristalina para uso como principio activo farmacéutico

by OLENIK, Britta, RUBENBAUER, Philipp, FEY, Peter, KÜSEL, Julia, SPINDLER, Felix, LOVIS, Kai
Year of Publication 23.10.2020

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Patent

Procedimiento de preparación de 5-fluoro-1h-pirazolopiridinas sustituidas

Procedimiento de preparación de 5-fluoro-1h-pirazolopiridinas sustituidas

by BIERER Donald, GRUNENEBERG Alfons, FEY PETER
Year of Publication 10.02.2017

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Patent

Procedimiento para la preparación de (3s)-3-(4-cloro-3-{[(2s,3r)-2-(4-clorofenil)-4,4,4-trifluor-3-metilbutanoil]amino}fenil)-3-ácido ciclopropilpropanoico y su forma cristalina para uso como principio activo farmacéutico

Procedimiento para la preparación de (3s)-3-(4-cloro-3-{[(2s,3r)-2-(4-clorofenil)-4,4,4-trifluor-3-metilbutanoil]amino}fenil)-3-ácido ciclopropilpropanoico y su forma cristalina para uso como principio activo farmacéutico

by OLENIK, Britta, RUBENBAUER, Philipp, FEY, Peter, KÜSEL, Julia, SPINDLER, Felix, LOVIS, Kai
Year of Publication 31.08.2020

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Patent

METHOD FOR PRODUCING (3S)-3-(4-CHLOR-3-{[(2S,3R< /i>)-2-(4-CHLORPHENYL)-4,4,4-TRIFLUOR-3-METHYLBUTANOYL]AMINO}PHE NYL)-3-CYCLO-PROPYLPROPANOIC ACID AND THE CRYSTALLINE FORM THEREOF FOR USE AS A PHARMACEUTICAL INGREDIENT

METHOD FOR PRODUCING (3S)-3-(4-CHLOR-3-{[(2S,3R< /i>)-2-(4-CHLORPHENYL)-4,4,4-TRIFLUOR-3-METHYLBUTANOYL]AMINO}PHE NYL)-3-CYCLO-PROPYLPROPANOIC ACID AND THE CRYSTALLINE FORM THEREOF FOR USE AS A PHARMACEUTICAL INGREDIENT

by OLENIK Britta, SPINDLER Felix, RUBENBAUER Philipp, FEY Peter, KÜSEL Julia, LOVIS Kai
Year of Publication 20.08.2020

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Patent

Method for separating methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4-dihydro-5-pyrimidine-carboxylate-racemate

Method for separating methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4-dihydro-5-pyrimidine-carboxylate-racemate

by GOLDMANN SIEGFRIED, FEY PETER
Year of Publication 02.12.2004

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Patent

Method for separating methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4-dihydro-5-pyrimidine-carboxylate-racemate

Method for separating methyl 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-6-methyl-1,4-dihydro-5-pyrimidine-carboxylate-racemate

by Goldmann, Siegfried, Fey, Peter
Year of Publication 02.12.2004

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Patent

FORMULACIÓN FARMACÉUTICA DE POLVO SECO PARA INHALACIÓN Y PROCESO DE PREPARACIÓN

FORMULACIÓN FARMACÉUTICA DE POLVO SECO PARA INHALACIÓN Y PROCESO DE PREPARACIÓN

by PARRY, MARK, WARD, DAVID, RICHTER, ANNETT, MUNDRY, TOBIAS, BOTHE, CLEMENS, OLENIK, BRITTA, FABER, HELENE, NAGELSCHMITZ, JOHANNES, BECKER, GUIDO, BECKER-PELSTER, EVA MARIA, RSLER, BERND, EGGER, JULIAN, HAHN, MICHAEL, FEY, PETER, SCHIRMER, HEIKO, KEIL, BIRGIT, TEREBESI, ILDIKO, LANG, DIETER, JUNG, DAVID, VITRE, CECILE, TINEL, HANNA, WEIMANN, GERRIT, SALEH, SOUNDOS, DIETZ, LISA
Year of Publication 27.03.2024

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Patent

METHOD FOR PRODUCING (3S)-3-(4-CHLOR-3-{[(2S,3R)-2-(4-CHLORPHENYL)-4,4,4-TRIFLUOR-3-METHYLBUTANOYL]AMINO}PHENYL)-3-CYCLO-PROPYLPROPANOIC ACID AND THE CRYSTALLINE FORM THEREOF FOR USE AS A PHARMACEUTICAL INGREDIENT

METHOD FOR PRODUCING (3S)-3-(4-CHLOR-3-{[(2S,3R)-2-(4-CHLORPHENYL)-4,4,4-TRIFLUOR-3-METHYLBUTANOYL]AMINO}PHENYL)-3-CYCLO-PROPYLPROPANOIC ACID AND THE CRYSTALLINE FORM THEREOF FOR USE AS A PHARMACEUTICAL INGREDIENT

by KUESEL JULIA, SPINDLER FELIX, OLENIK BRITTA, LOVIS KAI, RUBENBAUER PHILIPP, FEY PETER
Year of Publication 17.07.2020

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Patent

SÍNTESIS QUIRAL DE N-(3,4-DIFLUORO-2-[(2-FLUORO-4-YODOFENIL)AMINO]-6-METOXIFENIL}- 1-[2,3-DIHIDROXI-PROPIL]CICLOPROPANOSULFONAMIDAS

SÍNTESIS QUIRAL DE N-(3,4-DIFLUORO-2-[(2-FLUORO-4-YODOFENIL)AMINO]-6-METOXIFENIL}- 1-[2,3-DIHIDROXI-PROPIL]CICLOPROPANOSULFONAMIDAS

by FEY, PETER, MAYER, AGATHE, CHRISTINE
Year of Publication 13.11.2014

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Patent

PROCEDIMIENTO PARA LA PREPARACIÓN DE (3S)-3-(4-CLORO-3-{[(2S,3R)-2-(4-CLOROFENIL)-4,4,4-TRIFLUOR-3-METILBUTANOIL]AMINO}FENIL)-3-ÁCIDO CICLOPROPILPROPANOICO Y SU FORMA CRISTALINA PARA USO COMO PRINCIPIO ACTIVO FARMACÉUTICO

PROCEDIMIENTO PARA LA PREPARACIÓN DE (3S)-3-(4-CLORO-3-{[(2S,3R)-2-(4-CLOROFENIL)-4,4,4-TRIFLUOR-3-METILBUTANOIL]AMINO}FENIL)-3-ÁCIDO CICLOPROPILPROPANOICO Y SU FORMA CRISTALINA PARA USO COMO PRINCIPIO ACTIVO FARMACÉUTICO

by FEY, PETER, KSEL, JULIA, SPINDLER, FELIX, OLENIK, BRITTA, RUBENBAUER, PHILIPP, LOVIS, KAI
Year of Publication 17.06.2020

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Patent

Procedimientos para preparar n-(3,4-difluoro-2-[(2-fluoro-4-yodofenil)aminoj-6-metoxifenil)-1-(2,3-dihidroxipropil)-ciclopropanosulfonamidas; y un compuesto intermediario utilizado

Procedimientos para preparar n-(3,4-difluoro-2-[(2-fluoro-4-yodofenil)aminoj-6-metoxifenil)-1-(2,3-dihidroxipropil)-ciclopropanosulfonamidas; y un compuesto intermediario utilizado

by FEY, PETER, MAYER, AGATHE, CHRISTINE
Year of Publication 22.09.2014

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Patent

Process for preparing (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoic acid and its crystalline form for use as pharmaceutically active compound

Process for preparing (3S)-3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoic acid and its crystalline form for use as pharmaceutically active compound

by Felix SPINDLER, Kai LOVIS, Philipp RUBENBAUER, Peter FEY, Britta OLENIK, Julia KUSEL
Year of Publication 31.05.2020

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Patent

CHIRAL SYNTHESIS OF N-{3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMI NO]-6-METHOXYPHENYL}-1-[2,3-DIHYDROXY-PROPYL]CYCLOPROPANESULFONA MIDES

CHIRAL SYNTHESIS OF N-{3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMI NO]-6-METHOXYPHENYL}-1-[2,3-DIHYDROXY-PROPYL]CYCLOPROPANESULFONA MIDES

by AGATHE CHRISTINE MAYER, PETER FEY
Year of Publication 01.08.2014

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Patent

METHOD FOR SEPARATING METHYL 4-(2-CHLORO-4-FLUOROPHENYL)-2-(3,5-DIFLUORO-2-PYRIDINYL)-6-METHYL-1,4-DIHYDRO-5-PYRIMIDINE- CARBOXYLATE -RACEMATE

METHOD FOR SEPARATING METHYL 4-(2-CHLORO-4-FLUOROPHENYL)-2-(3,5-DIFLUORO-2-PYRIDINYL)-6-METHYL-1,4-DIHYDRO-5-PYRIMIDINE- CARBOXYLATE -RACEMATE

by FEY, PETER, GOLDMANN, SIEGFRIED
Year of Publication 10.03.2004

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Patent

Synthèse chirale de n-{3,4-difluoro-2-[(2-fluoro-4-iodophényl)amino]-6-méthoxyphényl}-1-[2,3-dihydroxy-propyl]

Synthèse chirale de n-{3,4-difluoro-2-[(2-fluoro-4-iodophényl)amino]-6-méthoxyphényl}-1-[2,3-dihydroxy-propyl]

by FEY, PETER, MAYER, AGATHE, CHRISTINE
Year of Publication 02.06.2014

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Patent

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