Safety, tolerability, pharmacokinetics, and pharmacodynamics of a TLR7 agonist prodrug RO6870868 in healthy volunteers
Grippo, Joseph F., Folitar, Ilia, Passe, Sharon, Jiang, Qiudi, Rodriguez, Ignacio, Fettner, Scott H., Calleja, Elizabeth
Published in Clinical and translational science (01.07.2021)
Published in Clinical and translational science (01.07.2021)
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The effect of rifampicin, a prototypical CYP3A4 inducer, on erlotinib pharmacokinetics in healthy subjects
Hamilton, Marta, Wolf, Julie L., Drolet, Daniel W., Fettner, Scott H., Rakhit, Ashok K., Witt, Karsten, Lum, Bert L.
Published in Cancer chemotherapy and pharmacology (01.03.2014)
Published in Cancer chemotherapy and pharmacology (01.03.2014)
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Effect of food on the pharmacokinetics of erlotinib, an orally active epidermal growth factor receptor tyrosine-kinase inhibitor, in healthy individuals
Ling, Jie, Fettner, Scott, Lum, Bert L, Riek, Myriam, Rakhit, Ashok
Published in Anti-cancer drugs (01.02.2008)
Published in Anti-cancer drugs (01.02.2008)
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The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition
Rakhit, Ashok, Pantze, Michael P., Fettner, Scott, Jones, Hannah M., Charoin, Jean-Eric, Riek, Myriam, Lum, Bert L., Hamilton, Marta
Published in European journal of clinical pharmacology (01.01.2008)
Published in European journal of clinical pharmacology (01.01.2008)
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Phase 1b Dose Escalation Study of Erlotinib in Combination with Infusional 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Advanced Solid Tumors
HANAUSKE, Axel-R, CASSIDY, Jim, SASTRE, Javier, BOILING, Claus, JONES, Robert J, RAKHIT, Ashok, FETTNER, Scott, BRENNSCHEIDT, Ulrich, FEYEREISLOVA, Andrea, DIAZ-RUBIO, Eduardo
Published in Clinical cancer research (15.01.2007)
Published in Clinical cancer research (15.01.2007)
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Phase I Trial of 40-kd Branched Pegylated Interferon Alfa-2a for Patients With Advanced Renal Cell Carcinoma
MOTZER, Robert J, RAKHIT, Ashok, GINSBERG, Michelle, RITTWEGER, Karen, VUKY, Jacqueline, YU, Richard, FETTNER, Scott, HOOFTMAN, Leon
Published in Journal of clinical oncology (01.03.2001)
Published in Journal of clinical oncology (01.03.2001)
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Phase I Evaluation of a 40-kDa Branched-Chain Long-Acting Pegylated IFN-α-2a With and Without Cytarabine in Patients with Chronic Myelogenous Leukemia
Talpaz, Moshe, Rakhit, Ashok, Rittweger, Karen, O'Brien, Susan, Cortes, Jorge, Fettner, Scott, Hooftman, Leon, Kantarjian, Hagop
Published in Clinical cancer research (01.09.2005)
Published in Clinical cancer research (01.09.2005)
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Safety and Pharmacokinetic Characterization of Nacubactam, a Novel β-Lactamase Inhibitor, Alone and in Combination with Meropenem, in Healthy Volunteers
Mallalieu, Navita L, Winter, Erica, Fettner, Scott, Patel, Katie, Zwanziger, Elke, Attley, Gemma, Rodriguez, Ignacio, Kano, Akiko, Salama, Sameeh M, Bentley, Darren, Geretti, Anna Maria
Published in Antimicrobial agents and chemotherapy (21.04.2020)
Published in Antimicrobial agents and chemotherapy (21.04.2020)
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Pharmacokinetic and Pharmacodynamic Analysis of Subcutaneous Tocilizumab in Patients With Rheumatoid Arthritis From 2 Randomized, Controlled Trials: SUMMACTA and BREVACTA
Abdallah, Hisham, Hsu, Joy C., Lu, Peng, Fettner, Scott, Zhang, Xiaoping, Douglass, Wendy, Bao, Min, Rowell, Lucy, Burmester, Gerd R., Kivitz, Alan
Published in Journal of clinical pharmacology (01.04.2017)
Published in Journal of clinical pharmacology (01.04.2017)
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Evidence of bioequivalence and positive patient user handling of a tocilizumab autoinjector
Fettner, Scott, Mela, Christopher, Wildenhahn, Florian, Tavanti, Monica, Wells, Christine, Douglass, Wendy, Mallalieu, Navita L.
Published in Expert opinion on drug delivery (04.05.2019)
Published in Expert opinion on drug delivery (04.05.2019)
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A171: Tocilizumab Dosing in Juvenile Idiopathic Arthritis: Optimizing for Different Juvenile Idiopathic Arthritis Type and Patient Body Weight
Lu, Peng, Hsu, Joy, Keane, Caroline, Fettner, Scott, Wang, Jianmei, Ruperto, Nicolino, Harari, Olivier, Brunner, Hermine, Benedetti, Fabrizio De
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2014)
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Pharmacokinetics and pharmacodynamics of tocilizumab after subcutaneous administration in patients with rheumatoid arthritis
Zhang, Xiaoping, Chen, Ya-Chi, Fettner, Scott, Rowell, Lucy, Gott, Tatiana, Grimsey, Paul, Unsworth, Adam
Published in International journal of clinical pharmacology and therapeutics (01.08.2013)
Published in International journal of clinical pharmacology and therapeutics (01.08.2013)
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Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer
Calvert, Hilary, Twelves, Chris, Ranson, Malcolm, Plummer, Ruth, Fettner, Scott, Pantze, Michael, Ling, Jie, Hamilton, Marta, Lum, Bert L, Rakhit, Ashok
Published in Anti-cancer drugs (01.08.2014)
Published in Anti-cancer drugs (01.08.2014)
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Assessment of disease-drug-drug interaction between single-dose tocilizumab and oral contraceptives in women with active rheumatoid arthritis
Zhang, Xiaoping, Rowell, Lucy, Fettner, Scott, Lau, Carol, Teuber, Denise
Published in International journal of clinical pharmacology and therapeutics (01.01.2014)
Published in International journal of clinical pharmacology and therapeutics (01.01.2014)
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Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: A dose-escalation study
Twelves, Chris, Trigo, José M, Jones, Rob, De Rosa, Flavio, Rakhit, Ashok, Fettner, Scott, Wright, Tonya, Baselga, José
Published in European journal of cancer (1990) (01.02.2008)
Published in European journal of cancer (1990) (01.02.2008)
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Characterization of AUCs from sparsely sampled populations in toxicology studies
Pai, S M, Fettner, S H, Hajian, G, Cayen, M N, Batra, V K
Published in Pharmaceutical research (01.09.1996)
Published in Pharmaceutical research (01.09.1996)
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Phase I evaluation of a 40-kDa branched-chain long-acting pegylated IFN-alpha-2a with and without cytarabine in patients with chronic myelogenous leukemia
Talpaz, Moshe, Rakhit, Ashok, Rittweger, Karen, O'Brien, Susan, Cortes, Jorge, Fettner, Scott, Hooftman, Leon, Kantarjian, Hagop
Published in Clinical cancer research (01.09.2005)
Published in Clinical cancer research (01.09.2005)
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Journal Article
Phase I Evaluation of a 40-kDa Branched-Chain Long-Acting Pegylated IFN-a-2a With and Without Cytarabine in Patients with Chronic Myelogenous Leukemia
Talpaz, Moshe, Rakhit, Ashok, Rittweger, Karen, O'Brien, Susan, Cortes, Jorge, Fettner, Scott, Hooftman, Leon, Kantarjian, Hagop
Published in Clinical cancer research (01.09.2005)
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Published in Clinical cancer research (01.09.2005)
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Phase I evaluation of a 40-kDa branched-chain long-acting pegylated IFN-α-2awith and without cytarabine in patients with chronic myelogenous leukemia
TALPAZ, Moshe, RAKHIT, Ashok, RITTWEGER, Karen, O'BRIEN, Susan, CORTES, Jorge, FETTNER, Scott, HOOFTMAN, Leon, KANTARJIAN, Hagop
Published in Clinical cancer research (2005)
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Published in Clinical cancer research (2005)
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