Astrocyte reactivity influences amyloid-β effects on tau pathology in preclinical Alzheimer's disease
Bellaver, Bruna, Povala, Guilherme, Ferreira, Pamela C L, Ferrari-Souza, João Pedro, Leffa, Douglas T, Lussier, Firoza Z, Benedet, Andréa L, Ashton, Nicholas J, Triana-Baltzer, Gallen, Kolb, Hartmuth C, Tissot, Cécile, Therriault, Joseph, Servaes, Stijn, Stevenson, Jenna, Rahmouni, Nesrine, Lopez, Oscar L, Tudorascu, Dana L, Villemagne, Victor L, Ikonomovic, Milos D, Gauthier, Serge, Zimmer, Eduardo R, Zetterberg, Henrik, Blennow, Kaj, Aizenstein, Howard J, Klunk, William E, Snitz, Beth E, Maki, Pauline, Thurston, Rebecca C, Cohen, Ann D, Ganguli, Mary, Karikari, Thomas K, Rosa-Neto, Pedro, Pascoal, Tharick A
Published in Nature medicine (01.07.2023)
Published in Nature medicine (01.07.2023)
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Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer's disease
Ferrari-Souza, João Pedro, Ferreira, Pâmela C L, Bellaver, Bruna, Tissot, Cécile, Wang, Yi-Ting, Leffa, Douglas T, Brum, Wagner S, Benedet, Andréa L, Ashton, Nicholas J, De Bastiani, Marco Antônio, Rocha, Andréia, Therriault, Joseph, Lussier, Firoza Z, Chamoun, Mira, Servaes, Stijn, Bezgin, Gleb, Kang, Min Su, Stevenson, Jenna, Rahmouni, Nesrine, Pallen, Vanessa, Poltronetti, Nina Margherita, Klunk, William E, Tudorascu, Dana L, Cohen, Ann D, Villemagne, Victor L, Gauthier, Serge, Blennow, Kaj, Zetterberg, Henrik, Souza, Diogo O, Karikari, Thomas K, Zimmer, Eduardo R, Rosa-Neto, Pedro, Pascoal, Tharick A
Published in Molecular psychiatry (01.11.2022)
Published in Molecular psychiatry (01.11.2022)
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Genetic risk for attention-deficit/hyperactivity disorder predicts cognitive decline and development of Alzheimer's disease pathophysiology in cognitively unimpaired older adults
Leffa, Douglas T, Ferrari-Souza, João Pedro, Bellaver, Bruna, Tissot, Cécile, Ferreira, Pamela C L, Brum, Wagner S, Caye, Arthur, Lord, Jodie, Proitsi, Petroula, Martins-Silva, Thais, Tovo-Rodrigues, Luciana, Tudorascu, Dana L, Villemagne, Victor L, Cohen, Ann D, Lopez, Oscar L, Klunk, William E, Karikari, Thomas K, Rosa-Neto, Pedro, Zimmer, Eduardo R, Molina, Brooke S G, Rohde, Luis Augusto, Pascoal, Tharick A
Published in Molecular psychiatry (01.03.2023)
Published in Molecular psychiatry (01.03.2023)
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Blood‐brain barrier integrity impacts the use of plasma amyloid‐β as a proxy of brain amyloid‐β pathology
Bellaver, Bruna, Puig‐Pijoan, Albert, Ferrari‐Souza, João Pedro, Leffa, Douglas T., Lussier, Firoza Z., Ferreira, Pamela C. L., Tissot, Cécile, Povala, Guilherme, Therriault, Joseph, Benedet, Andréa L., Ashton, Nicholas J., Servaes, Stijn, Chamoun, Mira, Stevenson, Jenna, Rahmouni, Nesrine, Vermeiren, Marie, Macedo, Arthur C., Fernández‐Lebrero, Aida, García‐Escobar, Greta, Navalpotro‐Gómez, Irene, Lopez, Oscar, Tudorascu, Dana L., Cohen, Ann, Villemagne, Victor L., Klunk, William E., Gauthier, Serge, Zimmer, Eduardo R., Karikari, Thomas K., Blennow, Kaj, Zetterberg, Henrik, Suárez‐Calvet, Marc, Rosa‐Neto, Pedro, Pascoal, Tharick A.
Published in Alzheimer's & dementia (01.09.2023)
Published in Alzheimer's & dementia (01.09.2023)
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Journal Article
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials
Ferreira, Pamela C L, Ferrari-Souza, João Pedro, Tissot, Cécile, Bellaver, Bruna, Leffa, Douglas T, Lussier, Firoza, Povala, Guilherme, Therriault, Joseph, Benedet, Andréa L, Ashton, Nicholas J, Cohen, Ann D, Lopez, Oscar L, Tudorascu, Dana L, Klunk, William E, Soucy, Jean-Paul, Gauthier, Serge, Villemagne, Victor, Zetterberg, Henrik, Blennow, Kaj, Rosa-Neto, Pedro, Zimmer, Eduardo R, Karikari, Thomas K, Pascoal, Tharick A
Published in Neurology (04.07.2023)
Published in Neurology (04.07.2023)
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Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals
Ferreira, Pamela C L, Therriault, Joseph, Tissot, Cécile, Ferrari-Souza, João Pedro, Benedet, Andréa L, Povala, Guilherme, Bellaver, Bruna, Leffa, Douglas T, Brum, Wagner S, Lussier, Firoza Z, Bezgin, Gleb, Servaes, Stijn, Vermeiren, Marie, Macedo, Arthur C, Cabrera, Arlec, Stevenson, Jenna, Triana-Baltzer, Gallen, Kolb, Hartmuth, Rahmouni, Nesrine, Klunk, William E, Lopez, Oscar L, Villemagne, Victor L, Cohen, Ann, Tudorascu, Dana L, Zimmer, Eduardo R, Karikari, Thomas K, Ashton, Nicholas J, Zetterberg, Henrik, Blennow, Kaj, Gauthier, Serge, Rosa-Neto, Pedro, Pascoal, Tharick A
Published in Alzheimer's & dementia (01.10.2023)
Published in Alzheimer's & dementia (01.10.2023)
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14-3-3 ζ/δ-reported early synaptic injury in Alzheimer's disease is independently mediated by sTREM2
Woo, M. S., Nilsson, J., Therriault, J., Rahmouni, N., Brinkmalm, A., Lessa Benedet, Andréa, Ashton, Nicholas J., Macedo, A. C., Servaes, S., Wang, Y. T., Tissot, C., Arias, J. F., Hosseini, S. A., Chamoun, M., Lussier, F. Z., Karikari, Thomas, Stevenson, J., Mayer, C., Ferrari-Souza, J. P., Kobayashi, E., Massarweh, G., Friese, M. A., Pascoal, T. A., Gauthier, S., Zetterberg, Henrik, Blennow, Kaj, Rosa-Neto, P.
Published in Journal of neuroinflammation (01.12.2023)
Published in Journal of neuroinflammation (01.12.2023)
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Astrocyte Biomarkers in Alzheimer Disease: A Systematic Review and Meta-analysis
Bellaver, Bruna, Ferrari-Souza, João Pedro, Uglione da Ros, Lucas, Carter, Stephen F, Rodriguez-Vieitez, Elena, Nordberg, Agneta, Pellerin, Luc, Rosa-Neto, Pedro, Leffa, Douglas Teixeira, Zimmer, Eduardo R
Published in Neurology (15.06.2021)
Published in Neurology (15.06.2021)
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APOE ε4 associates with microglial activation independently of Aβ plaques and tau tangles
Ferrari-Souza, João Pedro, Lussier, Firoza Z, Leffa, Douglas T, Therriault, Joseph, Tissot, Cécile, Bellaver, Bruna, Ferreira, Pâmela C L, Malpetti, Maura, Wang, Yi-Ting, Povala, Guilherme, Benedet, Andréa L, Ashton, Nicholas J, Chamoun, Mira, Servaes, Stijn, Bezgin, Gleb, Kang, Min Su, Stevenson, Jenna, Rahmouni, Nesrine, Pallen, Vanessa, Poltronetti, Nina Margherita, O'Brien, John T, Rowe, James B, Cohen, Ann D, Lopez, Oscar L, Tudorascu, Dana L, Karikari, Thomas K, Klunk, William E, Villemagne, Victor L, Soucy, Jean-Paul, Gauthier, Serge, Souza, Diogo O, Zetterberg, Henrik, Blennow, Kaj, Zimmer, Eduardo R, Rosa-Neto, Pedro, Pascoal, Tharick A
Published in Science advances (05.04.2023)
Published in Science advances (05.04.2023)
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Journal Article
APOEε4 potentiates amyloid β effects on longitudinal tau pathology
Ferrari-Souza, João Pedro, Bellaver, Bruna, Ferreira, Pâmela C L, Benedet, Andréa L, Povala, Guilherme, Lussier, Firoza Z, Leffa, Douglas T, Therriault, Joseph, Tissot, Cécile, Soares, Carolina, Wang, Yi-Ting, Chamoun, Mira, Servaes, Stijn, Macedo, Arthur C, Vermeiren, Marie, Bezgin, Gleb, Kang, Min Su, Stevenson, Jenna, Rahmouni, Nesrine, Pallen, Vanessa, Poltronetti, Nina Margherita, Cohen, Ann, Lopez, Oscar L, Klunk, William E, Soucy, Jean-Paul, Gauthier, Serge, Souza, Diogo O, Triana-Baltzer, Gallen, Saad, Ziad S, Kolb, Hartmuth C, Karikari, Thomas K, Villemagne, Victor L, Tudorascu, Dana L, Ashton, Nicholas J, Zetterberg, Henrik, Blennow, Kaj, Zimmer, Eduardo R, Rosa-Neto, Pedro, Pascoal, Tharick A
Published in Nature aging (01.10.2023)
Published in Nature aging (01.10.2023)
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