Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients
Fernando, Tharu M., Piskol, Robert, Bainer, Russell, Sokol, Ethan S., Trabucco, Sally E., Zhang, Qing, Trinh, Huong, Maund, Sophia, Kschonsak, Marc, Chaudhuri, Subhra, Modrusan, Zora, Januario, Thomas, Yauch, Robert L.
Published in Nature communications (03.11.2020)
Published in Nature communications (03.11.2020)
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Journal Article
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
Cayrol, Florencia, Praditsuktavorn, Pannee, Fernando, Tharu M., Kwiatkowski, Nicholas, Marullo, Rosella, Calvo-Vidal, M. Nieves, Phillip, Jude, Pera, Benet, Yang, Shao Ning, Takpradit, Kaipol, Roman, Lidia, Gaudiano, Marcello, Crescenzo, Ramona, Ruan, Jia, Inghirami, Giorgio, Zhang, Tinghu, Cremaschi, Graciela, Gray, Nathanael S., Cerchietti, Leandro
Published in Nature communications (30.01.2017)
Published in Nature communications (30.01.2017)
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Journal Article
VERONICA: Randomized Phase II Study of Fulvestrant and Venetoclax in ER-Positive Metastatic Breast Cancer Post-CDK4/6 Inhibitors - Efficacy, Safety, and Biomarker Results
Lindeman, Geoffrey J, Fernando, Tharu M, Bowen, Rebecca, Jerzak, Katarzyna J, Song, Xinni, Decker, Thomas, Boyle, Frances, McCune, Steve, Armstrong, Anne, Shannon, Catherine, Bertelli, Gianfilippo, Chang, Ching-Wei, Desai, Rupal, Gupta, Kushagra, Wilson, Timothy R, Flechais, Aulde, Bardia, Aditya
Published in Clinical cancer research (02.08.2022)
Published in Clinical cancer research (02.08.2022)
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Journal Article
PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival
Lu, Xiaoqing, Fernando, Tharu M., Lossos, Chen, Yusufova, Nevin, Liu, Fan, Fontán, Lorena, Durant, Matthew, Geng, Huimin, Melnick, Jacob, Luo, Yuan, Vega, Francisco, Moy, Vincent, Inghirami, Giorgio, Nimer, Stephen, Melnick, Ari M., Lossos, Izidore S.
Published in Blood (08.11.2018)
Published in Blood (08.11.2018)
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Journal Article
Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas
Culjkovic-Kraljacic, Biljana, Fernando, Tharu M., Marullo, Rossella, Calvo-Vidal, Nieves, Verma, Akanksha, Yang, ShaoNing, Tabbò, Fabrizio, Gaudiano, Marcello, Zahreddine, Hiba, Goldstein, Rebecca L., Patel, Jayeshkumar, Taldone, Tony, Chiosis, Gabriela, Ladetto, Marco, Ghione, Paola, Machiorlatti, Rodolfo, Elemento, Olivier, Inghirami, Giorgio, Melnick, Ari, Borden, Katherine L.B., Cerchietti, Leandro
Published in Blood (18.02.2016)
Published in Blood (18.02.2016)
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Journal Article
Neoadjuvant palbociclib plus either giredestrant or anastrozole in oestrogen receptor-positive, HER2-negative, early breast cancer (coopERA Breast Cancer): an open-label, randomised, controlled, phase 2 study
Hurvitz, Sara A, Bardia, Aditya, Quiroga, Vanesa, Park, Yeon Hee, Blancas, Isabel, Alonso-Romero, José Luis, Vasiliev, Aleksandr, Adamchuk, Hryhoriy, Salgado, Marcelo, Yardley, Denise A, Berzoy, Oleksandr, Zamora-Auñón, Pilar, Chan, David, Spera, Gonzalo, Xue, Cloris, Ferreira, Erika, Badovinac Crnjevic, Tanja, Pérez-Moreno, Pablo Diego, López-Valverde, Vanesa, Steinseifer, Jutta, Fernando, Tharu M, Moore, Heather M, Fasching, Peter A
Published in The lancet oncology (01.09.2023)
Published in The lancet oncology (01.09.2023)
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Journal Article
BCL6 Evolved to Enable Stress Tolerance in Vertebrates and Is Broadly Required by Cancer Cells to Adapt to Stress
Fernando, Tharu M, Marullo, Rossella, Pera Gresely, Benet, Phillip, Jude M, Yang, Shao Ning, Lundell-Smith, Geoffrey, Torregroza, Ingrid, Ahn, Haelee, Evans, Todd, Győrffy, Balázs, Privé, Gilbert G, Hirano, Masayuki, Melnick, Ari M, Cerchietti, Leandro
Published in Cancer discovery (01.05.2019)
Published in Cancer discovery (01.05.2019)
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Journal Article
Next-Generation Estrogen Receptor-Targeted Therapeutics
Fernando, Tharu M, Moore, Heather M, Wongchenko, Matthew J, Metcalfe, Ciara
Published in Annual review of cancer biology (11.04.2023)
Published in Annual review of cancer biology (11.04.2023)
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Journal Article
Corrigendum: THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
Cayrol, Florencia, Praditsuktavorn, Pannee, Fernando, Tharu M, Kwiatkowski, Nicholas, Marullo, Rossella, Calvo-Vidal, M Nieves, Phillip, Jude, Pera, Benet, Yang, Shao Ning, Takpradit, Kaipol, Roman, Lidia, Gaudiano, Marcello, Crescenzo, Ramona, Ruan, Jia, Inghirami, Giorgio, Zhang, Tinghu, Cremaschi, Graciela, Gray, Nathanael S, Cerchietti, Leandro
Published in Nature communications (20.02.2017)
Published in Nature communications (20.02.2017)
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Journal Article
Correction: Corrigendum: THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors
Cayrol, Florencia, Praditsuktavorn, Pannee, Fernando, Tharu M., Kwiatkowski, Nicholas, Marullo, Rossella, Calvo-Vidal, M. Nieves, Phillip, Jude, Pera, Benet, Yang, Shao Ning, Takpradit, Kaipol, Roman, Lidia, Gaudiano, Marcello, Crescenzo, Ramona, Ruan, Jia, Inghirami, Giorgio, Zhang, Tinghu, Cremaschi, Graciela, Gray, Nathanael S, Cerchietti, Leandro
Published in Nature communications (20.02.2017)
Published in Nature communications (20.02.2017)
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Journal Article
Abstract PD13-06: Neoadjuvant giredestrant (GDC-9545) + palbociclib versus anastrozole + palbociclib in postmenopausal women with estrogen receptor-positive, HER2-negative, untreated early breast cancer: Primary analysis of the randomized, open-label, phase II coopERA breast cancer study
Hurvitz, Sara A, Quiroga, Vanesa, Park, Yeon Hee, Bardia, Aditya, López-Valverde, Vanesa, Steinseifer, Jutta, Fernando, Tharu M, Spera, Gonzalo, Xue, Cloris, Fasching, Peter A
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Journal Article
Abstract P5-13-06: Exploratory biomarker analysis in VERONICA, a phase 2 study of venetoclax + fulvestrant versus fulvestrant in patients with estrogen receptor (ER)-positive HER2-negative metastatic breast cancer (mBC)
Lindeman, Geoffrey J., Fernando, Tharu M., Bowen, Rebecca, Chang, Ching-Wei, Desai, Rupal, Gupta, Kushagra, Fléchais, Aulde, Wilson, Timothy R., Bardia, Aditya
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Journal Article
Abstract OT-28-03: VICKI: A Phase Ib/II, randomized, placebo-controlled, study of venetoclax plus ado-trastuzumab emtansine (T-DM1) in patients (pts) with previously treated HER2-positive locally advanced (LA) or metastatic breast cancer (MBC)
Lindeman, Geoffrey J, Hamilton, Erika, Krop, Ian, Lim, Bora, Modi, Shanu, Saura, Cristina, Desai, Rupal, Danner, Bradford J, Fernando, Tharu M, Kong, Shengchun, Legrand, Fatema A, Nasroulah, Federico
Published in Cancer research (Chicago, Ill.) (15.02.2021)
Published in Cancer research (Chicago, Ill.) (15.02.2021)
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Journal Article
Abstract 5869: Characterization and therapeutic implications of SMARCA4 mutations in cancer
Fernando, Tharu M., Piskol, Robert, Bainer, Russell, Sokol, Ethan, Trabucco, Sally, Zhang, Qing, Trinh, Huong, Maund, Sophia, Kschonsak, Marc, Chaudhuri, Subhra, Januario, Tom, Modrusan, Zora, Yauch, Robert L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Results from VERONICA: A randomized, phase II study of second-/third-line venetoclax (VEN) + fulvestrant (F) versus F alone in estrogen receptor (ER)-positive, HER2-negative, locally advanced, or metastatic breast cancer (LA/MBC)
Lindeman, Geoffrey J, Bowen, Rebecca, Jerzak, Katarzyna Joanna, Song, Xinni, Decker, Thomas, Boyle, Frances M., McCune, Steven L., Armstrong, Anne, Shannon, Catherine M., Bertelli, Gianfilippo, Fernando, Tharu M, Desai, Rupal, Gupta, Kushagra, Hsu, Jerry Y., Flechais, Aulde, Bardia, Aditya
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
Neoadjuvant giredestrant (GDC-9545) plus palbociclib (P) versus anastrozole (A) plus P in postmenopausal women with estrogen receptor–positive, HER2-negative, untreated early breast cancer (ER+/HER2– eBC): Final analysis of the randomized, open-label, international phase 2 coopERA BC study
Fasching, Peter A., Bardia, Aditya, Quiroga, Vanesa, Park, Yeon Hee, Blancas, Isabel, Alonso, Jose Luis, Vasilyev, Alexander, Adamchuk, Hryhoriy, Salgado, Marcelo Ramos Tejo, Yardley, Denise A., Spera, Gonzalo, Xue, Cloris, Ferreira, Erika, Badovinac Crnjevic, Tanja, Pérez-Moreno, Pablo Diego, López-Valverde, Vanesa, Steinseifer, Jutta, Fernando, Tharu M., Moore, Heather M., Hurvitz, Sara A.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Abstract P6-04-09: Variations in diagnostic practice of Ki67 scoring suggest standard guidelines needed for pathological assessment: survey results of global Ki67 testing methods
Moore, Heather M., Lin, Wendy W., Fernando, Tharu M., Lopez, Celine, Kent, Emma, Ellouk, Karine, Giltnane, Jennifer M.
Published in Cancer research (Chicago, Ill.) (01.03.2023)
Published in Cancer research (Chicago, Ill.) (01.03.2023)
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Journal Article
BCL6 Mediates a Stress Tolerance Phenotype through Its BTB Domain
Fernando, Tharu M, Yang, Shao Ning, Huang, Chuanxin, Chiosis, Gabriela, Cerchietti, Leandro, Melnick, Ari M.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Abstract 6120: Genomic profiling of KRAS and EGFR -altered non-squamous non-small cell lung cancer reveal ancestry-specific co-alterations with therapeutic implications
Sisoudiya, Saumya D., Houle, Armande A., Fernando, Tharu M., Wilson, Timothy R., Schutzman, Jennifer L., Lee, Jessica K., Schrock, Alexa B., Sokol, Ethan S., Sivakumar, Smruthy, Shi, Zhen, Pathria, Gaurav
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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