Upregulation of Orai Channels Contributes to Aging-Related Vascular Alterations in Rat Coronary Arteries
Angulo, Javier, Fernández, Argentina, Sevilleja-Ortiz, Alejandro, Sánchez-Ferrer, Alberto, Rodríguez-Mañas, Leocadio, El Assar, Mariam
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
Get full text
Journal Article
PKC Inhibition Improves Human Penile Vascular Function and the NO/cGMP Pathway in Diabetic Erectile Dysfunction: The Role of NADPH Oxidase
El Assar, Mariam, La Fuente, José M, Sosa, Patricia, Fernández, Argentina, Pepe-Cardoso, Augusto J, Martínez-Salamanca, Juan I, Rodríguez-Mañas, Leocadio, Angulo, Javier
Published in International journal of molecular sciences (01.03.2024)
Published in International journal of molecular sciences (01.03.2024)
Get full text
Journal Article
Short-term pharmacological activation of Nrf2 ameliorates vascular dysfunction in aged rats and in pathological human vasculature. A potential target for therapeutic intervention
Angulo, Javier, El Assar, Mariam, Sevilleja-Ortiz, Alejandro, Fernández, Argentina, Sánchez-Ferrer, Alberto, Romero-Otero, Javier, Martínez-Salamanca, Juan I, La Fuente, José M, Rodríguez-Mañas, Leocadio
Published in Redox biology (01.09.2019)
Published in Redox biology (01.09.2019)
Get full text
Journal Article
Oxidized soluble guanylyl cyclase causes erectile dysfunction in alcoholic mice
Olivencia, Miguel A., Gil de Biedma‐Elduayen, Leticia, Giménez‐Gómez, Pablo, Barreira, Bianca, Fernández, Argentina, Angulo, Javier, Colado, Maria Isabel, O'Shea, Esther, Perez‐Vizcaino, Francisco
Published in British journal of pharmacology (01.09.2023)
Published in British journal of pharmacology (01.09.2023)
Get full text
Journal Article
L-cysteine/hydrogen sulfide pathway induces cGMP-dependent relaxation of corpus cavernosum and penile arteries from patients with erectile dysfunction and improves arterial vasodilation induced by PDE5 inhibition
La Fuente, José M., Fernández, Argentina, Pepe-Cardoso, Augusto J., Martínez-Salamanca, Juan I., Louro, Nuno, Angulo, Javier
Published in European journal of pharmacology (15.11.2019)
Published in European journal of pharmacology (15.11.2019)
Get full text
Journal Article
Multivessel analysis of progressive vascular aging in the rat: Asynchronous vulnerability among vascular territories
El Assar, Mariam, Fernández, Argentina, Sánchez-Ferrer, Alberto, Angulo, Javier, Rodríguez-Mañas, Leocadio
Published in Mechanisms of ageing and development (01.07.2018)
Published in Mechanisms of ageing and development (01.07.2018)
Get full text
Journal Article
STIM/Orai Inhibition as a Strategy for Alleviating Diabetic Erectile Dysfunction Through Modulation of Rat and Human Penile Tissue Contractility and in vivo Potentiation of Erectile Responses
Sevilleja-Ortiz, Alejandro, El Assar, Mariam, García-Gómez, Borja, La Fuente, José M., Alonso-Isa, Manuel, Romero-Otero, Javier, Martínez-Salamanca, Juan I., Fernández, Argentina, Rodríguez-Mañas, Leocadio, Angulo, Javier
Published in Journal of sexual medicine (01.12.2022)
Published in Journal of sexual medicine (01.12.2022)
Get full text
Journal Article
LDL-c/HDL-c Ratio and NADPH-Oxidase-2-Derived Oxidative Stress as Main Determinants of Microvascular Endothelial Function in Morbidly Obese Subjects
Santos, Jorge, La Fuente, José M, Fernández, Argentina, Ruano, Paula, Angulo, Javier
Published in Antioxidants (20.09.2024)
Published in Antioxidants (20.09.2024)
Get full text
Journal Article
Erectile dysfunction is associated with defective L-cysteine/hydrogen sulfide pathway in human corpus cavernosum and penile arteries
La Fuente, José M., Sevilleja-Ortiz, Alejandro, García-Rojo, Esther, El Assar, Mariam, Fernández, Argentina, Pepe-Cardoso, Augusto J., Martínez-Salamanca, Juan I., Romero-Otero, Javier, Rodríguez-Mañas, Leocadio, Angulo, Javier
Published in European journal of pharmacology (05.10.2020)
Published in European journal of pharmacology (05.10.2020)
Get full text
Journal Article
Ageing-induced hypercontractility is related to functional enhancement of STIM/Orai and upregulation of Orai 3 in rat and human penile tissue
Sevilleja-Ortiz, Alejandro, El Assar, Mariam, García-Rojo, Esther, García-Gómez, Borja, Fernández, Argentina, Sánchez-Ferrer, Alberto, La Fuente, José M., Romero-Otero, Javier, Rodríguez-Mañas, Leocadio, Angulo, Javier
Published in Mechanisms of ageing and development (01.12.2021)
Published in Mechanisms of ageing and development (01.12.2021)
Get full text
Journal Article
Tadalafil enhances the inhibitory effects of tamsulosin on neurogenic contractions of human prostate and bladder neck
Angulo, Javier, Cuevas, Pedro, Fernández, Argentina, La Fuente, José M, Allona, Antonio, Moncada, Ignacio, Sáenz de Tejada, Iñigo
Published in Journal of sexual medicine (01.09.2012)
Published in Journal of sexual medicine (01.09.2012)
Get more information
Journal Article
Functional Role of STIM-1 and Orai1 in Human Microvascular Aging
El Assar, Mariam, García-Rojo, Esther, Sevilleja-Ortiz, Alejandro, Sánchez-Ferrer, Alberto, Fernández, Argentina, García-Gómez, Borja, Romero-Otero, Javier, Rodríguez-Mañas, Leocadio, Angulo, Javier
Published in Cells (Basel, Switzerland) (01.11.2022)
Published in Cells (Basel, Switzerland) (01.11.2022)
Get full text
Journal Article
Early manifestation of aging-related vascular dysfunction in human penile vasculature—A potential explanation for the role of erectile dysfunction as a harbinger of systemic vascular disease
Assar, Mariam El, Angulo, Javier, García-Rojo, Esther, Sevilleja-Ortiz, Alejandro, García-Gómez, Borja, Fernández, Argentina, Sánchez-Ferrer, Alberto, La Fuente, José M., Romero-Otero, Javier, Rodríguez-Mañas, Leocadio
Published in GeroScience (01.02.2022)
Published in GeroScience (01.02.2022)
Get full text
Journal Article
Dual Strategy With Oral Phosphodiesterase Type 5 Inhibition and Intracavernosal Implantation of Mesenchymal Stem Cells Is Superior to Individual Approaches in the Recovery of Erectile and Cavernosal Functions After Cavernous Nerve Injury in Rats
Martínez-Salamanca, Juan I, Zurita, Mercedes, Costa, Carla, Martínez-Salamanca, Eduardo, Fernández, Argentina, Castela, Angela, Vaquero, Jesús, Carballido, Joaquín, Angulo, Javier
Published in Journal of sexual medicine (01.01.2016)
Published in Journal of sexual medicine (01.01.2016)
Get more information
Journal Article
Enhanced Contribution of Orai Channels to Contractility of Human Penile Smooth Muscle in Erectile Dysfunction
Sevilleja-Ortiz, Alejandro, El Assar, Mariam, García-Rojo, Esther, Romero-Otero, Javier, García-Gómez, Borja, Fernández, Argentina, Medina-Polo, José, La Fuente, José M., Rodríguez-Mañas, Leocadio, Angulo, Javier
Published in Journal of sexual medicine (01.05.2020)
Published in Journal of sexual medicine (01.05.2020)
Get full text
Journal Article
Diabetes exacerbates the functional deficiency of NO/cGMP pathway associated with erectile dysfunction in human corpus cavernosum and penile arteries
Angulo, Javier, González-Corrochano, Rocío, Cuevas, Pedro, Fernández, Argentina, La Fuente, José M, Rolo, Francisco, Allona, Antonio, Sáenz de Tejada, Iñigo
Published in Journal of sexual medicine (01.02.2010)
Published in Journal of sexual medicine (01.02.2010)
Get more information
Journal Article
Stimulation of large-conductance calcium-activated potassium channels inhibits neurogenic contraction of human bladder from patients with urinary symptoms and reverses acetic acid-induced bladder hyperactivity in rats
La Fuente, José M., Fernández, Argentina, Cuevas, Pedro, González-Corrochano, Rocío, Chen, Mao Xiang, Angulo, Javier
Published in European journal of pharmacology (15.07.2014)
Published in European journal of pharmacology (15.07.2014)
Get full text
Journal Article
Nitrergic function is lost but endothelial function is preserved in the corpus cavernosum and penile resistance arteries of men after radical prostatectomy
Martínez-Salamanca, Juan I, La Fuente, José M, Fernández, Argentina, Martínez-Salamanca, Eduardo, Pepe-Cardoso, Augusto J, Carballido, Joaquín, Angulo, Javier
Published in Journal of sexual medicine (01.03.2015)
Published in Journal of sexual medicine (01.03.2015)
Get more information
Journal Article
Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate
Angulo, Javier, Peiró, Concepción, Romacho, Tania, Fernández, Argentina, Cuevas, Begoña, González-Corrochano, Rocío, Giménez-Gallego, Guillermo, de Tejada, Iñigo Sáenz, Sánchez-Ferrer, Carlos F., Cuevas, Pedro
Published in European journal of pharmacology (30.09.2011)
Published in European journal of pharmacology (30.09.2011)
Get full text
Journal Article
Nebivolol potentiates the efficacy of PDE5 inhibitors to relax corpus cavernosum and penile arteries from diabetic patients by enhancing the NO/cGMP pathway
Martínez-Salamanca, Juan I, La Fuente, José M, Cardoso, José, Fernández, Argentina, Cuevas, Pedro, Wright, Harold M, Angulo, Javier
Published in Journal of sexual medicine (01.05.2014)
Published in Journal of sexual medicine (01.05.2014)
Get more information
Journal Article