Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
Rogers, Corey, Erkes, Dan A, Nardone, Alexandria, Aplin, Andrew E, Fernandes-Alnemri, Teresa, Alnemri, Emad S
Published in Nature communications (11.04.2019)
Published in Nature communications (11.04.2019)
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Journal Article
SUMO-mediated regulation of NLRP3 modulates inflammasome activity
Barry, Rachael, John, Sidonie Wicky, Liccardi, Gianmaria, Tenev, Tencho, Jaco, Isabel, Chen, Chih-Hong, Choi, Justin, Kasperkiewicz, Paulina, Fernandes-Alnemri, Teresa, Alnemri, Emad, Drag, Marcin, Chen, Yuan, Meier, Pascal
Published in Nature communications (01.08.2018)
Published in Nature communications (01.08.2018)
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Journal Article
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
FERNANDES-ALNEMRI, Teresa, YU, Je-Wook, DATTA, Pinaki, JIANGHONG WU, AINEMRI, Emad S
Published in Nature (26.03.2009)
Published in Nature (26.03.2009)
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Journal Article
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
Kang, Seokwon, Fernandes-Alnemri, Teresa, Rogers, Corey, Mayes, Lindsey, Wang, Ying, Dillon, Christopher, Roback, Linda, Kaiser, William, Oberst, Andrew, Sagara, Junji, Fitzgerald, Katherine A, Green, Douglas R, Zhang, Jianke, Mocarski, Edward S, Alnemri, Emad S
Published in Nature communications (24.06.2015)
Published in Nature communications (24.06.2015)
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Journal Article
Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome
Juliana, Christine, Fernandes-Alnemri, Teresa, Wu, Jianghong, Datta, Pinaki, Solorzano, Leobaldo, Yu, Je-Wook, Meng, Rong, Quong, Andrew A., Latz, Eicke, Scott, Charles P., Alnemri, Emad S.
Published in The Journal of biological chemistry (26.03.2010)
Published in The Journal of biological chemistry (26.03.2010)
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Journal Article
Inflammasome priming by lipopolysaccharide is dependent upon ERK signaling and proteasome function
Ghonime, Mohammed G, Shamaa, Obada R, Das, Srabani, Eldomany, Ramadan A, Fernandes-Alnemri, Teresa, Alnemri, Emad S, Gavrilin, Mikhail A, Wewers, Mark D
Published in The Journal of immunology (1950) (15.04.2014)
Published in The Journal of immunology (1950) (15.04.2014)
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Journal Article
Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
Mayes-Hopfinger, Lindsey, Enache, Aura, Xie, Jian, Huang, Chou-Long, Köchl, Robert, Tybulewicz, Victor L J, Fernandes-Alnemri, Teresa, Alnemri, Emad S
Published in Nature communications (27.07.2021)
Published in Nature communications (27.07.2021)
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Journal Article
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
Fernandes-Alnemri, Teresa, Datta, Pinaki, Huang, Lan, Juliana, Christine, Eisenlohr, Laurence, Yu, Je-Wook, Landel, Carlisle P, Alnemri, Emad S, Kang, Seokwon, Solorzano, Leobaldo, McCormick, Margaret, Wu, Jianghong, McDermott, Erin
Published in Nature immunology (01.05.2010)
Published in Nature immunology (01.05.2010)
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Journal Article
Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection
Fang, Rendong, Tsuchiya, Kohsuke, Kawamura, Ikuo, Shen, Yanna, Hara, Hideki, Sakai, Shunsuke, Yamamoto, Takeshi, Fernandes-Alnemri, Teresa, Yang, Ruili, Hernandez-Cuellar, Eduardo, Dewamitta, Sita R, Xu, Yanting, Qu, Huixin, Alnemri, Emad S, Mitsuyama, Masao
Published in The Journal of immunology (1950) (01.11.2011)
Published in The Journal of immunology (1950) (01.11.2011)
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Journal Article
Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 Mutants
Yu, Je-Wook, Fernandes-Alnemri, Teresa, Datta, Pinaki, Wu, Jianghong, Juliana, Christine, Solorzano, Leobaldo, McCormick, Margaret, Zhang, ZhiJia, Alnemri, Emad S.
Published in Molecular cell (26.10.2007)
Published in Molecular cell (26.10.2007)
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Journal Article
Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction
Hegde, Ramesh, Srinivasula, Srinivasa M., Zhang, ZhiJia, Wassell, Richard, Mukattash, Rula, Cilenti, Lucia, DuBois, Garrett, Lazebnik, Yuri, Zervos, Antonis S., Fernandes-Alnemri, Teresa, Alnemri, Emad S.
Published in The Journal of biological chemistry (04.01.2002)
Published in The Journal of biological chemistry (04.01.2002)
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Journal Article
Non‐transcriptional regulation of NLRP3 inflammasome signaling by IL‐4
Hwang, Inhwa, Yang, Jungmin, Hong, Sujeong, Ju Lee, Eun, Lee, Seung‐Hyo, Fernandes‐Alnemri, Teresa, Alnemri, Emad S, Yu, Je‐Wook
Published in Immunology and cell biology (01.07.2015)
Published in Immunology and cell biology (01.07.2015)
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Journal Article
Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability
Paulin, Nicole, Viola, Joana R, Maas, Sanne L, de Jong, Renske, Fernandes-Alnemri, Teresa, Weber, Christian, Drechsler, Maik, Döring, Yvonne, Soehnlein, Oliver
Published in Circulation (New York, N.Y.) (17.07.2018)
Published in Circulation (New York, N.Y.) (17.07.2018)
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Journal Article
Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization
Srinivasula, Srinivasa M., Ahmad, Manzoor, Fernandes-Alnemri, Teresa, Alnemri, Emad S.
Published in Molecular cell (01.06.1998)
Published in Molecular cell (01.06.1998)
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Journal Article
Identification of Ipaf, a Human Caspase-1-activating Protein Related to Apaf-1
Poyet, J L, Srinivasula, S M, Tnani, M, Razmara, M, Fernandes-Alnemri, T, Alnemri, E S
Published in The Journal of biological chemistry (27.07.2001)
Published in The Journal of biological chemistry (27.07.2001)
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