Biomarker Assay Validation by Mass Spectrometry
Fernández-Metzler, Carmen, Ackermann, Brad, Garofolo, Fabio, Arnold, Mark E., DeSilva, Binodh, Gu, Huidong, Laterza, Omar, Mao, Yan, Rose, Mark, Vazvaei-Smith, Faye, Steenwyk, Rick
Published in The AAPS journal (09.05.2022)
Published in The AAPS journal (09.05.2022)
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Journal Article
Collection of selected reaction monitoring and full scan data on a time scale suitable for target compound quantitative analysis by liquid chromatography/tandem mass spectrometry
King, Richard C., Gundersdorf, Richard, Fernández-Metzler, Carmen L.
Published in Rapid communications in mass spectrometry (01.01.2003)
Published in Rapid communications in mass spectrometry (01.01.2003)
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Journal Article
Riluzole prodrugs for melanoma and ALS: Design, synthesis, and in vitro metabolic profiling
McDonnell, Mark E., Vera, Matthew D., Blass, Benjamin E., Pelletier, Jeffrey C., King, Richard C., Fernandez-Metzler, Carmen, Smith, Garry R., Wrobel, Jay, Chen, Suzie, Wall, Brian A., Reitz, Allen B.
Published in Bioorganic & medicinal chemistry (15.09.2012)
Published in Bioorganic & medicinal chemistry (15.09.2012)
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Journal Article
Rapid Lipid Mediator Profiling by Convergence Chromatography-MS/MS
Metzler, Guille, King, Richard C, Fernández-Metzler, Carmen, Das, Amitava, Davis, T Gregg, Bajrami, Besnik, Bretschneider, Tom, Kvaskoff, David
Published in Methods in molecular biology (Clifton, N.J.) (2025)
Published in Methods in molecular biology (Clifton, N.J.) (2025)
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Journal Article
Prostaglandin Metabolites Analysis in Urine by LC-MS/MS
Metzler, Guille, Day, Lily A, King, Richard C, Fernández-Metzler, Carmen, Das, Amitava, Davis, T Gregg, Bajrami, Besnik, Bretschneider, Tom, Kvaskoff, David
Published in Methods in molecular biology (Clifton, N.J.) (2025)
Published in Methods in molecular biology (Clifton, N.J.) (2025)
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Journal Article
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP
Roecker, Anthony J., Coleman, Paul J., Mercer, Swati P., Schreier, John D., Buser, Carolyn A., Walsh, Eileen S., Hamilton, Kelly, Lobell, Robert B., Tao, Weikang, Diehl, Ronald E., South, Vicki J., Davide, Joseph P., Kohl, Nancy E., Yan, Youwei, Kuo, Lawrence C., Li, Chunze, Fernandez-Metzler, Carmen, Mahan, Elizabeth A., Prueksaritanont, Thomayant, Hartman, George D.
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
Published in Bioorganic & medicinal chemistry letters (15.10.2007)
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The emergence and application of technological advances in biotransformation studies
Fernandez-Metzler, Carmen L, King, Richard C
Published in Current topics in medicinal chemistry (01.01.2002)
Published in Current topics in medicinal chemistry (01.01.2002)
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Journal Article
Is Incurred Sample Reanalysis (ISR) Applicable in Biomarker Assays?
Hays, Amanda, Amaravadi, Lakshmi, Fernandez-Metzler, Carmen, King, Lindsay, Mathews, Joel, Ni, Yan, Quadrini, Karen, Tinder, Chunyan, Vazvaei, Faye, Zeng, Jianing
Published in The AAPS journal (01.05.2022)
Published in The AAPS journal (01.05.2022)
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Journal Article
Kinesin Spindle Protein (KSP) Inhibitors. 9. Discovery of (2S)-4-(2,5-Difluorophenyl)-N-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the Treatment of Taxane-Refractory Cancer
Cox, Christopher D, Coleman, Paul J, Breslin, Michael J, Whitman, David B, Garbaccio, Robert M, Fraley, Mark E, Buser, Carolyn A, Walsh, Eileen S, Hamilton, Kelly, Schaber, Michael D, Lobell, Robert B, Tao, Weikang, Davide, Joseph P, Diehl, Ronald E, Abrams, Marc T, South, Vicki J, Huber, Hans E, Torrent, Maricel, Prueksaritanont, Thomayant, Li, Chunze, Slaughter, Donald E, Mahan, Elizabeth, Fernandez-Metzler, Carmen, Yan, Youwei, Kuo, Lawrence C, Kohl, Nancy E, Hartman, George D
Published in Journal of medicinal chemistry (24.07.2008)
Published in Journal of medicinal chemistry (24.07.2008)
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Journal Article
Abstract 3788: Routine micro-sampling and LC-MS/MS quantitation for PK and PK/PD determination in mice
Fernandez-Metzler, Carmen, King, Richard C., Wilson, Denielle, Machin, Amanda, Otto, Todd, Franklin, Marshall
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Nonpeptide αvβ3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent αvβ3 Antagonist for the Prevention and Treatment of Osteoporosis
Hutchinson, John H, Halczenko, Wasyl, Brashear, Karen M, Breslin, Michael J, Coleman, Paul J, Duong, Le T, Fernandez-Metzler, Carmen, Gentile, Michael A, Fisher, John E, Hartman, George D, Huff, Joel R, Kimmel, Donald B, Leu, Chih-Tai, Meissner, Robert S, Merkle, Kara, Nagy, Rose, Pennypacker, Brenda, Perkins, James J, Prueksaritanont, Thomayant, Rodan, Gideon A, Varga, Sandor L, Wesolowski, Greg A, Zartman, Amy E, Rodan, Sevgi B, Duggan, Mark E
Published in Journal of medicinal chemistry (23.10.2003)
Published in Journal of medicinal chemistry (23.10.2003)
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